Abstract
OBJECTIVE—To measure the health related quality of life (QoL) following mitral valve replacement in childhood. DESIGN—Cross sectional study. SETTING—Tertiary referral centre. METHODS—19 patients, median age (range) 14.4 (9.7-25.4) years, were studied at a median of 7.6 (0.5-11.2) years after their most recent mitral valve replacement. General health status was measured using age specific validated questionnaires. Ten children aged between 9-15 years completed the child health related quality of life questionnaire, and for nine older patients the UK version of the short form 36 was used. Specific questions were added to the existing questionnaires to study the effect of long term anticoagulation treatment. RESULTS—All patients in the younger age group reported impaired QoL. Five rated their QoL within the range of children with chronic physical disabilities, and in the remaining five it was worse. In the older age group, all but two patients perceived their QoL as normal or near normal compared with a reference population matched for sex and age. Having regular blood tests had a negative effect on QoL in three young children, and one older patient reported impaired QoL related to taking daily warfarin tablets. CONCLUSIONS—In this small group, the effect of mitral valve replacement on QoL appears to be age specific, with more impairment in younger children. Long term anticoagulation treatment is well tolerated in most patients. Keywords: prosthetic mitral valve; heart valve replacement; child; quality of life
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Selected References
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- Almeida R. S., Elliott M. J., Robinson P. J., Wyse R. K., Taylor J. F., Stark J., de Leval M. R. Surgery for congenital abnormalities of the mitral valve at the Hospital for Sick Children, London from 1969-1983. J Cardiovasc Surg (Torino) 1988 Jan-Feb;29(1):95–99. [PubMed] [Google Scholar]
- Brazier J. E., Harper R., Jones N. M., O'Cathain A., Thomas K. J., Usherwood T., Westlake L. Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992 Jul 18;305(6846):160–164. doi: 10.1136/bmj.305.6846.160. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Garratt A. M., Ruta D. A., Abdalla M. I., Buckingham J. K., Russell I. T. The SF36 health survey questionnaire: an outcome measure suitable for routine use within the NHS? BMJ. 1993 May 29;306(6890):1440–1444. doi: 10.1136/bmj.306.6890.1440. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Harada Y., Imai Y., Kurosawa H., Ishihara K., Kawada M., Fukuchi S. Ten-year follow-up after valve replacement with the St. Jude Medical prosthesis in children. J Thorac Cardiovasc Surg. 1990 Aug;100(2):175–180. [PubMed] [Google Scholar]
- Hasenkam J. M., Kimose H. H., Knudsen L., Grønnesby H., Halborg J., Christensen T. D., Attermann J., Pilegaard H. K. Self management of oral anticoagulant therapy after heart valve replacement. Eur J Cardiothorac Surg. 1997 May;11(5):935–942. doi: 10.1016/s1010-7940(97)01204-9. [DOI] [PubMed] [Google Scholar]
- Kadoba K., Jonas R. A., Mayer J. E., Castaneda A. R. Mitral valve replacement in the first year of life. J Thorac Cardiovasc Surg. 1990 Nov;100(5):762–768. [PubMed] [Google Scholar]
- Pal D. K. Quality of life assessment in children: a review of conceptual and methodological issues in multidimensional health status measures. J Epidemiol Community Health. 1996 Aug;50(4):391–396. doi: 10.1136/jech.50.4.391. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zweng T. N., Bluett M. K., Mosca R., Callow L. B., Bove E. L. Mitral valve replacement in the first 5 years of life. Ann Thorac Surg. 1989 May;47(5):720–724. doi: 10.1016/0003-4975(89)90126-4. [DOI] [PubMed] [Google Scholar]
- van Doorn C., Yates R., Tsang V., deLeval M., Elliott M. Mitral valve replacement in children: mortality, morbidity, and haemodynamic status up to medium term follow up. Heart. 2000 Dec;84(6):636–642. doi: 10.1136/heart.84.6.636. [DOI] [PMC free article] [PubMed] [Google Scholar]