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Figure 1 .
Schematic diagram of myocardial kinetics of radiographic and MRI contrast agents. (A) They transiently enter the extravascular space during normal circumstances. (B) The extravasation is increased as a result of increased endothelial permeability during microvascular injury. (C) The increased resistance in the distal capillary bed from the "no-reflow" phenomenon can accentuate this effect. (D) The duration of extravasation is prolonged beyond the intravascular duration of the dye when the size of the extravascular space increases as in myocardial oedema.