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. 1995 Jan;63(1):345–348. doi: 10.1128/iai.63.1.345-348.1995

Expression of the Arp protein, a member of the M protein family, is not sufficient to inhibit phagocytosis of Streptococcus pyogenes.

L K Husmann 1, J R Scott 1, G Lindahl 1, L Stenberg 1
PMCID: PMC172998  PMID: 7806375

Abstract

Many Streptococcus pyogenes immunoglobulin-binding proteins have structural similarities to the antiphagocytic M protein, including the well-known C repeats. One of these molecules is the immunoglobulin A-binding protein Arp, which is expressed by a serotype 4 strain for which no antiphagocytic M protein has yet been described. We expressed Arp4 in an S. pyogenes strain from which the structural gene for the M protein has been deleted and found that Arp4 is not sufficient to inhibit phagocytosis.

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Selected References

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