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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 2000 Apr;53(4):255–265. doi: 10.1136/jcp.53.4.255

Neuropathology

W Timperley
PMCID: PMC1731172  PMID: 10823120

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Figure 1 Sections of the brainstem that are useful in the investigation of neurodegenerative disease. (a) The medulla at the level of the olivary nuclei; (b) the medulla/pons transition; (c) the cerebellum to include the tonsil; (d) the midpons; (e) the cerebellum to include the vermis and dentate nuclei; (f) the midbrain at the level of the inferior colliculi; (g) the midbrain at the level of the superior colliculi.

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Figure 2 Sections of the brainstem that are useful in the investigation of neurodegenerative disease. (A) The frontal lobe to include the middle frontal gyrus. (B) The midfrontal lobe to include the head of the caudate nucleus and periventricular white matter. (C) The anterior cingulate gyrus. (D) The temporal lobe at the level of the mamillary body to include the amygdaloid and lentiform nuclei. (E) The temporal lobe to include the superior and middle temporal gyri, and the posterior frontal lobe to include the underlying cingulate gyrus. (F) The temporal lobe at the level of the lateral geniculate body, including the hippocampus. (G) The parietal lobe at the level of the pulvinar to include the periventricular white matter. (H) the midparietal lobe to include the inferior parietal lobule. (I) The occipital lobe to include the periventricular white matter and the calcarine cortex.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bell J. E., Ironside J. W. How to tackle a possible Creutzfeldt-Jakob disease necropsy. J Clin Pathol. 1993 Mar;46(3):193–197. doi: 10.1136/jcp.46.3.193. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Coons S. W., Johnson P. C. Regional heterogeneity in the DNA content of human gliomas. Cancer. 1993 Nov 15;72(10):3052–3060. doi: 10.1002/1097-0142(19931115)72:10<3052::aid-cncr2820721030>3.0.co;2-7. [DOI] [PubMed] [Google Scholar]
  3. Daumas-Duport C., Scheithauer B., O'Fallon J., Kelly P. Grading of astrocytomas. A simple and reproducible method. Cancer. 1988 Nov 15;62(10):2152–2165. doi: 10.1002/1097-0142(19881115)62:10<2152::aid-cncr2820621015>3.0.co;2-t. [DOI] [PubMed] [Google Scholar]
  4. Davidson G. S., So K. P. Rapid immunoperoxidase staining of axons for frozen section diagnosis of nerve biopsy specimens. J Clin Pathol. 1989 May;42(5):551–554. doi: 10.1136/jcp.42.5.551. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Hoshino T., Nagashima T., Murovic J. A., Wilson C. B., Edwards M. S., Gutin P. H., Davis R. L., DeArmond S. J. In situ cell kinetics studies on human neuroectodermal tumors with bromodeoxyuridine labeling. J Neurosurg. 1986 Mar;64(3):453–459. doi: 10.3171/jns.1986.64.3.0453. [DOI] [PubMed] [Google Scholar]
  6. Ironside J. W., Bell J. E. The 'high-risk' neuropathological autopsy in AIDS and Creutzfeldt-Jakob disease: principles and practice. Neuropathol Appl Neurobiol. 1996 Oct;22(5):388–393. doi: 10.1111/j.1365-2990.1996.tb00908.x. [DOI] [PubMed] [Google Scholar]
  7. Kaur B., Rutty G. N., Timperley W. R. The possible role of hypoxia in the formation of axonal bulbs. J Clin Pathol. 1999 Mar;52(3):203–209. doi: 10.1136/jcp.52.3.203. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Kleihues P., Burger P. C., Scheithauer B. W. The new WHO classification of brain tumours. Brain Pathol. 1993 Jul;3(3):255–268. doi: 10.1111/j.1750-3639.1993.tb00752.x. [DOI] [PubMed] [Google Scholar]
  9. Slavin G., Sowter C., Ward P., Paton K. Measurement of striated muscle fibre diameters using interactive computer-aided microscopy. J Clin Pathol. 1982 Nov;35(11):1268–1271. doi: 10.1136/jcp.35.11.1268. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. So P. C. An easy way to orientate small muscle biopsy tissue. J Clin Pathol. 1985 Nov;38(11):1312–1313. doi: 10.1136/jcp.38.11.1312. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. van der Valk P. Prion diseases: what will be next? J Clin Pathol. 1998 Apr;51(4):265–269. doi: 10.1136/jcp.51.4.265. [DOI] [PMC free article] [PubMed] [Google Scholar]

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