Abstract
Study objective: To analyse if socioeconomic characteristics in area of living affect the risk of myocardial infarction in a Swedish urban population, and to evaluate to what extent the contextual effect is confounded by the individual exposures.
Design: A population based case-referent study (SHEEP).
Setting: Cases (n=1631) were all incident first events of myocardial infarction during 1992–1994. The study base included all Swedish citizens aged 45–70 years, living in Stockholm metropolitan area during these years. The social context of all metropolitan parishes (n=89) was determined by routine statistics on 21 socioeconomic indicators. A factor analysis of the socioeconomic indicators resulted in three dimensions of socioeconomic deprivation, which were analysed separately as three different contextual exposures.
Main results: The main characteristics of the extracted factors were; class structure, social exclusion and poverty. Among men, there were increased relative risks of similar magnitudes (1.28 to 1.33) in the more deprived areas according to all three dimensions of the socioeconomic context. However, when adjusting for individual exposures, the poverty factor had the strongest contextual impact. The contextual effects among women showed a different pattern. In comparison with women living the most affluent areas according to the class structure index, women in the rest of Stockholm metropolitan area had nearly 70% higher risk of myocardial infarction after adjustment for individual social exposures.
Conclusions: The results suggest that the socioeconomic context in area of living increases the risk of myocardial infarction. The increased risk in only partially explained by individual social factors (the compositional effect).
Full Text
The Full Text of this article is available as a PDF (130.3 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Anderson R. T., Sorlie P., Backlund E., Johnson N., Kaplan G. A. Mortality effects of community socioeconomic status. Epidemiology. 1997 Jan;8(1):42–47. doi: 10.1097/00001648-199701000-00007. [DOI] [PubMed] [Google Scholar]
- Andersson P. A., Varde E., Diderichsen F. Modelling of resource allocation to health care authorities in Stockholm county. Health Care Manag Sci. 2000 Feb;3(2):141–149. doi: 10.1023/a:1019045408441. [DOI] [PubMed] [Google Scholar]
- Blakely T. A., Woodward A. J. Ecological effects in multi-level studies. J Epidemiol Community Health. 2000 May;54(5):367–374. doi: 10.1136/jech.54.5.367. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Carstairs V. Deprivation indices: their interpretation and use in relation to health. J Epidemiol Community Health. 1995 Dec;49 (Suppl 2):S3–S8. doi: 10.1136/jech.49.suppl_2.s3. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Diderichsen F., Varde E., Whitehead M. Resource allocation to health authorities: the quest for an equitable formula in Britain and Sweden. BMJ. 1997 Oct 4;315(7112):875–878. doi: 10.1136/bmj.315.7112.875. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Diez-Roux A. V. Bringing context back into epidemiology: variables and fallacies in multilevel analysis. Am J Public Health. 1998 Feb;88(2):216–222. doi: 10.2105/ajph.88.2.216. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Diez-Roux A. V. Multilevel analysis in public health research. Annu Rev Public Health. 2000;21:171–192. doi: 10.1146/annurev.publhealth.21.1.171. [DOI] [PubMed] [Google Scholar]
- Diez-Roux A. V., Nieto F. J., Muntaner C., Tyroler H. A., Comstock G. W., Shahar E., Cooper L. S., Watson R. L., Szklo M. Neighborhood environments and coronary heart disease: a multilevel analysis. Am J Epidemiol. 1997 Jul 1;146(1):48–63. doi: 10.1093/oxfordjournals.aje.a009191. [DOI] [PubMed] [Google Scholar]
- Drever F., Whitehead M. Mortality in regions and local authority districts in the 1990s: exploring the relationship with deprivation. Popul Trends. 1995 Winter;(82):19–26. [PubMed] [Google Scholar]
- Ellaway A., Anderson A., Macintyre S. Does area of residence affect body size and shape? Int J Obes Relat Metab Disord. 1997 Apr;21(4):304–308. doi: 10.1038/sj.ijo.0800405. [DOI] [PubMed] [Google Scholar]
- Ellaway A., Macintyre S. Does where you live predict health related behaviours?: a case study in Glasgow. Health Bull (Edinb) 1996 Nov;54(6):443–446. [PubMed] [Google Scholar]
- Haan M., Kaplan G. A., Camacho T. Poverty and health. Prospective evidence from the Alameda County Study. Am J Epidemiol. 1987 Jun;125(6):989–998. doi: 10.1093/oxfordjournals.aje.a114637. [DOI] [PubMed] [Google Scholar]
- Hart C., Ecob R., Smith G. D. People, places and coronary heart disease risk factors: a multilevel analysis of the Scottish Heart Health Study archive. Soc Sci Med. 1997 Sep;45(6):893–902. doi: 10.1016/s0277-9536(96)00431-5. [DOI] [PubMed] [Google Scholar]
- Jarman B. Underprivileged areas: validation and distribution of scores. Br Med J (Clin Res Ed) 1984 Dec 8;289(6458):1587–1592. doi: 10.1136/bmj.289.6458.1587. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kaplan G. A., Pamuk E. R., Lynch J. W., Cohen R. D., Balfour J. L. Inequality in income and mortality in the United States: analysis of mortality and potential pathways. BMJ. 1996 Apr 20;312(7037):999–1003. doi: 10.1136/bmj.312.7037.999. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kaplan G. A. People and places: contrasting perspectives on the association between social class and health. Int J Health Serv. 1996;26(3):507–519. doi: 10.2190/4CUU-7B3G-G4XR-0K0B. [DOI] [PubMed] [Google Scholar]
- Karvonen S., Rimpelä A. H. Urban small area variation in adolescents' health behaviour. Soc Sci Med. 1997 Oct;45(7):1089–1098. doi: 10.1016/s0277-9536(97)00036-1. [DOI] [PubMed] [Google Scholar]
- Karvonen S., Rimpelä A. Socio-regional context as a determinant of adolescents' health behaviour in Finland. Soc Sci Med. 1996 Nov;43(10):1467–1474. doi: 10.1016/0277-9536(96)00044-5. [DOI] [PubMed] [Google Scholar]
- Kaufman J. S., Cooper R. S., McGee D. L. Socioeconomic status and health in blacks and whites: the problem of residual confounding and the resiliency of race. Epidemiology. 1997 Nov;8(6):621–628. [PubMed] [Google Scholar]
- Kennedy B. P., Kawachi I., Prothrow-Stith D. Income distribution and mortality: cross sectional ecological study of the Robin Hood index in the United States. BMJ. 1996 Apr 20;312(7037):1004–1007. doi: 10.1136/bmj.312.7037.1004. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LeClere F. B., Rogers R. G., Peters K. Neighborhood social context and racial differences in women's heart disease mortality. J Health Soc Behav. 1998 Jun;39(2):91–107. [PubMed] [Google Scholar]
- Lynch J. W., Kaplan G. A., Pamuk E. R., Cohen R. D., Heck K. E., Balfour J. L., Yen I. H. Income inequality and mortality in metropolitan areas of the United States. Am J Public Health. 1998 Jul;88(7):1074–1080. doi: 10.2105/ajph.88.7.1074. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lynch J. W., Smith G. D., Kaplan G. A., House J. S. Income inequality and mortality: importance to health of individual income, psychosocial environment, or material conditions. BMJ. 2000 Apr 29;320(7243):1200–1204. doi: 10.1136/bmj.320.7243.1200. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Malmström M., Johansson S. E., Sundquist J. A hierarchical analysis of long-term illness and mortality in socially deprived areas. Soc Sci Med. 2001 Aug;53(3):265–275. doi: 10.1016/s0277-9536(00)00291-4. [DOI] [PubMed] [Google Scholar]
- Malmström M., Sundquist J., Bajekal M., Johansson S. E. Indices of need and social deprivation for primary health care. Scand J Soc Med. 1998 Jun;26(2):124–130. doi: 10.1177/14034948980260021301. [DOI] [PubMed] [Google Scholar]
- Reijneveld S. A., Schene A. H. Higher prevalence of mental disorders in socioeconomically deprived urban areas in The Netherlands: community or personal disadvantage? J Epidemiol Community Health. 1998 Jan;52(1):2–7. doi: 10.1136/jech.52.1.2. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Reijneveld S. A. The impact of individual and area characteristics on urban socioeconomic differences in health and smoking. Int J Epidemiol. 1998 Feb;27(1):33–40. doi: 10.1093/ije/27.1.33. [DOI] [PubMed] [Google Scholar]
- Reijneveld S. A., Verheij R. A., de Bakker D. H. The impact of area deprivation on differences in health: does the choice of the geographical classification matter? J Epidemiol Community Health. 2000 Apr;54(4):306–313. doi: 10.1136/jech.54.4.306. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Reuterwall C., Hallqvist J., Ahlbom A., De Faire U., Diderichsen F., Hogstedt C., Pershagen G., Theorell T., Wiman B., Wolk A. Higher relative, but lower absolute risks of myocardial infarction in women than in men: analysis of some major risk factors in the SHEEP study. The SHEEP Study Group. J Intern Med. 1999 Aug;246(2):161–174. doi: 10.1046/j.1365-2796.1999.00554.x. [DOI] [PubMed] [Google Scholar]
- Robert S. A. Community-level socioeconomic status effects on adult health. J Health Soc Behav. 1998 Mar;39(1):18–37. [PubMed] [Google Scholar]
- Shouls S., Congdon P., Curtis S. Modelling inequality in reported long term illness in the UK: combining individual and area characteristics. J Epidemiol Community Health. 1996 Jun;50(3):366–376. doi: 10.1136/jech.50.3.366. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Smith G. D., Hart C., Watt G., Hole D., Hawthorne V. Individual social class, area-based deprivation, cardiovascular disease risk factors, and mortality: the Renfrew and Paisley Study. J Epidemiol Community Health. 1998 Jun;52(6):399–405. doi: 10.1136/jech.52.6.399. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Smith G. D., Neaton J. D., Wentworth D., Stamler R., Stamler J. Socioeconomic differentials in mortality risk among men screened for the Multiple Risk Factor Intervention Trial: I. White men. Am J Public Health. 1996 Apr;86(4):486–496. doi: 10.2105/ajph.86.4.486. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sundquist J., Malmström M., Johansson S. E. Cardiovascular risk factors and the neighbourhood environment: a multilevel analysis. Int J Epidemiol. 1999 Oct;28(5):841–845. doi: 10.1093/ije/28.5.841. [DOI] [PubMed] [Google Scholar]
- Waitzman N. J., Smith K. R. Phantom of the area: poverty-area residence and mortality in the United States. Am J Public Health. 1998 Jun;88(6):973–976. doi: 10.2105/ajph.88.6.973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Waitzman N. J., Smith K. R. Separate but lethal: the effects of economic segregation on mortality in metropolitan America. Milbank Q. 1998;76(3):341-73, 304. doi: 10.1111/1468-0009.00095. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wilkinson R. G. Income distribution and life expectancy. BMJ. 1992 Jan 18;304(6820):165–168. doi: 10.1136/bmj.304.6820.165. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yen I. H., Kaplan G. A. Neighborhood social environment and risk of death: multilevel evidence from the Alameda County Study. Am J Epidemiol. 1999 May 15;149(10):898–907. doi: 10.1093/oxfordjournals.aje.a009733. [DOI] [PubMed] [Google Scholar]
- Yen I. H., Kaplan G. A. Poverty area residence and changes in depression and perceived health status: evidence from the Alameda County Study. Int J Epidemiol. 1999 Feb;28(1):90–94. doi: 10.1093/ije/28.1.90. [DOI] [PubMed] [Google Scholar]
- Yen I. H., Kaplan G. A. Poverty area residence and changes in physical activity level: evidence from the Alameda County Study. Am J Public Health. 1998 Nov;88(11):1709–1712. doi: 10.2105/ajph.88.11.1709. [DOI] [PMC free article] [PubMed] [Google Scholar]