Skip to main content
Journal of Epidemiology and Community Health logoLink to Journal of Epidemiology and Community Health
. 2002 Jan;56(1):24–28. doi: 10.1136/jech.56.1.24

Types of alcoholic beverages and blood lipids in a French population

J Ruidavets 1, P Ducimetiere 1, D Arveiler 1, P Amouyel 1, A Bingham 1, A Wagner 1, D Cottel 1, B Perret 1, J Ferrieres 1
PMCID: PMC1732002  PMID: 11801616

Abstract

Study objective: Prospective studies have shown a consistent relation between alcohol consumption and decreasing incidence of coronary artery disease. The protective effect of alcohol could be mediated through increased levels of HDL cholesterol (HDL-c). The aim of this study was to examine the relation between blood lipid levels and the consumption of different types of alcoholic beverages among 1581 men and 1535 women.

Design: Data from representative cross sectional surveys (1994–1997) in three different regions of France were used. The consumption of the different types of alcohol was quantified using a recall method according to a typical weekly consumption.

Main results: The median daily alcohol intake was 24 g for men and 4 g for women. After adjustment for confounders, total alcohol showed a positive and significant association with HDL-c and triglycerides (TG) in both sexes. In multivariate analysis, wine was positively associated with HDL-c. Beer was positively associated with HDL-c in men and with triglycerides in men and women. When taking drinking patterns into account, wine drinkers had higher HDL-c levels than non-wine drinkers. Differences became non-significant after adjustment for confounders and particularly for socioeconomic parameters.

Conclusions: In a French population sample, total alcohol was positively associated with HDL-c and triglycerides. The specific influence of any particular alcoholic beverage on blood lipids was not clearly demonstrated but wine preference found in a group with higher lifestyle standards was associated with a more favourable blood lipid profile.

Full Text

The Full Text of this article is available as a PDF (120.5 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brenn T. The Tromsø heart study: alcoholic beverages and coronary risk factors. J Epidemiol Community Health. 1986 Sep;40(3):249–256. doi: 10.1136/jech.40.3.249. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Castelli W. P., Doyle J. T., Gordon T., Hames C. G., Hjortland M. C., Hulley S. B., Kagan A., Zukel W. J. Alcohol and blood lipids. The cooperative lipoprotein phenotyping study. Lancet. 1977 Jul 23;2(8030):153–155. doi: 10.1016/s0140-6736(77)90176-3. [DOI] [PubMed] [Google Scholar]
  3. Choudhury S. R., Ueshima H., Kita Y., Kobayashi K. M., Okayama A., Yamakawa M., Hirao Y., Ishikawa M., Miyoshi Y. Alcohol intake and serum lipids in a Japanese population. Int J Epidemiol. 1994 Oct;23(5):940–947. doi: 10.1093/ije/23.5.940. [DOI] [PubMed] [Google Scholar]
  4. Criqui M. H., Cowan L. D., Tyroler H. A., Bangdiwala S., Heiss G., Wallace R. B., Cohn R. Lipoproteins as mediators for the effects of alcohol consumption and cigarette smoking on cardiovascular mortality: results form the Lipid Research Clinics Follow-up Study. Am J Epidemiol. 1987 Oct;126(4):629–637. doi: 10.1093/oxfordjournals.aje.a114702. [DOI] [PubMed] [Google Scholar]
  5. Evans A. E., Ruidavets J. B., McCrum E. E., Cambou J. P., McClean R., Douste-Blazy P., McMaster D., Bingham A., Patterson C. C., Richard J. L. Autres pays, autres coeurs? Dietary patterns, risk factors and ischaemic heart disease in Belfast and Toulouse. QJM. 1995 Jul;88(7):469–477. [PubMed] [Google Scholar]
  6. Friedewald W. T., Levy R. I., Fredrickson D. S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972 Jun;18(6):499–502. [PubMed] [Google Scholar]
  7. Gaziano J. M., Buring J. E., Breslow J. L., Goldhaber S. Z., Rosner B., VanDenburgh M., Willett W., Hennekens C. H. Moderate alcohol intake, increased levels of high-density lipoprotein and its subfractions, and decreased risk of myocardial infarction. N Engl J Med. 1993 Dec 16;329(25):1829–1834. doi: 10.1056/NEJM199312163292501. [DOI] [PubMed] [Google Scholar]
  8. Gaziano J. M., Hennekens C. H., Godfried S. L., Sesso H. D., Glynn R. J., Breslow J. L., Buring J. E. Type of alcoholic beverage and risk of myocardial infarction. Am J Cardiol. 1999 Jan 1;83(1):52–57. doi: 10.1016/s0002-9149(98)00782-6. [DOI] [PubMed] [Google Scholar]
  9. Grønbaek M., Deis A., Sørensen T. I., Becker U., Schnohr P., Jensen G. Mortality associated with moderate intakes of wine, beer, or spirits. BMJ. 1995 May 6;310(6988):1165–1169. doi: 10.1136/bmj.310.6988.1165. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hartung G. H., Foreyt J. P., Mitchell R. E., Mitchell J. G., Reeves R. S., Gotto A. M., Jr Effect of alcohol intake on high-density lipoprotein cholesterol levels in runners and inactive men. JAMA. 1983 Feb 11;249(6):747–750. [PubMed] [Google Scholar]
  11. Hulley S. B., Gordon S. Alcohol and high-density lipoprotein cholesterol: causal inference from diverse study designs. Circulation. 1981 Sep;64(3 Pt 2):III–63. [PubMed] [Google Scholar]
  12. Klatsky A. L., Armstrong M. A. Alcoholic beverage choice and risk of coronary artery disease mortality: do red wine drinkers fare best? Am J Cardiol. 1993 Feb 15;71(5):467–469. doi: 10.1016/0002-9149(93)90460-t. [DOI] [PubMed] [Google Scholar]
  13. Langer R. D., Criqui M. H., Reed D. M. Lipoproteins and blood pressure as biological pathways for effect of moderate alcohol consumption on coronary heart disease. Circulation. 1992 Mar;85(3):910–915. doi: 10.1161/01.cir.85.3.910. [DOI] [PubMed] [Google Scholar]
  14. Linn S., Carroll M., Johnson C., Fulwood R., Kalsbeek W., Briefel R. High-density lipoprotein cholesterol and alcohol consumption in US white and black adults: data from NHANES II. Am J Public Health. 1993 Jun;83(6):811–816. doi: 10.2105/ajph.83.6.811. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Marques-Vidal P., Arveiler D., Evans A., Montaye M., Bingham A., Ruidavets J. B., McMaster D., Haas B., Amouyel P., Ducimetière P. Patterns of alcohol consumption in middle-aged men from France and Northern Ireland. The PRIME study. Eur J Clin Nutr. 2000 Apr;54(4):321–328. doi: 10.1038/sj.ejcn.1600954. [DOI] [PubMed] [Google Scholar]
  16. Marques-Vidal P., Ducimetière P., Evans A., Cambou J. P., Arveiler D. Alcohol consumption and myocardial infarction: a case-control study in France and Northern Ireland. Am J Epidemiol. 1996 Jun 1;143(11):1089–1093. doi: 10.1093/oxfordjournals.aje.a008683. [DOI] [PubMed] [Google Scholar]
  17. Marques-Vidal P., Sie P., Cambou J. P., Chap H., Perret B. Relationships of plasminogen activator inhibitor activity and lipoprotein(a) with insulin, testosterone, 17 beta-estradiol, and testosterone binding globulin in myocardial infarction patients and healthy controls. J Clin Endocrinol Metab. 1995 Jun;80(6):1794–1798. doi: 10.1210/jcem.80.6.7775625. [DOI] [PubMed] [Google Scholar]
  18. Parker D. R., McPhillips J. B., Derby C. A., Gans K. M., Lasater T. M., Carleton R. A. High-density-lipoprotein cholesterol and types of alcoholic beverages consumed among men and women. Am J Public Health. 1996 Jul;86(7):1022–1027. doi: 10.2105/ajph.86.7.1022. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Paunio M., Virtamo J., Gref C. G., Heinonen O. P. Serum high density lipoprotein cholesterol, alcohol, and coronary mortality in male smokers. BMJ. 1996 May 11;312(7040):1200–1203. doi: 10.1136/bmj.312.7040.1200. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Poikolainen K., Vartiainen E. Wine and good subjective health. Am J Epidemiol. 1999 Jul 1;150(1):47–50. doi: 10.1093/oxfordjournals.aje.a009917. [DOI] [PubMed] [Google Scholar]
  21. Rimm E. B., Giovannucci E. L., Willett W. C., Colditz G. A., Ascherio A., Rosner B., Stampfer M. J. Prospective study of alcohol consumption and risk of coronary disease in men. Lancet. 1991 Aug 24;338(8765):464–468. doi: 10.1016/0140-6736(91)90542-w. [DOI] [PubMed] [Google Scholar]
  22. Stampfer M. J., Colditz G. A., Willett W. C., Speizer F. E., Hennekens C. H. A prospective study of moderate alcohol consumption and the risk of coronary disease and stroke in women. N Engl J Med. 1988 Aug 4;319(5):267–273. doi: 10.1056/NEJM198808043190503. [DOI] [PubMed] [Google Scholar]
  23. Suh I., Shaten B. J., Cutler J. A., Kuller L. H. Alcohol use and mortality from coronary heart disease: the role of high-density lipoprotein cholesterol. The Multiple Risk Factor Intervention Trial Research Group. Ann Intern Med. 1992 Jun 1;116(11):881–887. doi: 10.7326/0003-4819-116-11-881. [DOI] [PubMed] [Google Scholar]
  24. The World Health Organization MONICA Project (monitoring trends and determinants in cardiovascular disease): a major international collaboration. WHO MONICA Project Principal Investigators. J Clin Epidemiol. 1988;41(2):105–114. doi: 10.1016/0895-4356(88)90084-4. [DOI] [PubMed] [Google Scholar]
  25. Tjønneland A., Grønbaek M., Stripp C., Overvad K. Wine intake and diet in a random sample of 48763 Danish men and women. Am J Clin Nutr. 1999 Jan;69(1):49–54. doi: 10.1093/ajcn/69.1.49. [DOI] [PubMed] [Google Scholar]
  26. Wannamethee S. G., Shaper A. G. Type of alcoholic drink and risk of major coronary heart disease events and all-cause mortality. Am J Public Health. 1999 May;89(5):685–690. doi: 10.2105/ajph.89.5.685. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Woodward M., Tunstall-Pedoe H. Alcohol consumption, diet, coronary risk factors, and prevalent coronary heart disease in men and women in the Scottish heart health study. J Epidemiol Community Health. 1995 Aug;49(4):354–362. doi: 10.1136/jech.49.4.354. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Yano K., Reed D. M., McGee D. L. Ten-year incidence of coronary heart disease in the Honolulu Heart Program. Relationship to biologic and lifestyle characteristics. Am J Epidemiol. 1984 May;119(5):653–666. doi: 10.1093/oxfordjournals.aje.a113787. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Epidemiology and Community Health are provided here courtesy of BMJ Publishing Group

RESOURCES