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. 1995 Jul;63(7):2773–2775. doi: 10.1128/iai.63.7.2773-2775.1995

Phenotypic modulation of gonococcal lipooligosaccharide in acidic and alkaline culture.

R K Pettit 1, E S Martin 1, S M Wagner 1, V J Bertolino 1
PMCID: PMC173372  PMID: 7790098

Abstract

Neisseria gonorrhoeae infects a diverse array of niches in its human host, which expose the organism to dramatic variations in pH. We examined growth and lipooligosaccharide expression of two gonococcal strains in liquid and solid cultures under acidic, neutral, and alkaline conditions. Growth rates in broth were similar under the three conditions, and the pH remained fairly constant throughout the growth cycle. Altered lipooligosaccharide expression at the different pHs was noted in both plate- and broth-grown organisms.

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Selected References

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