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Journal of Medical Ethics logoLink to Journal of Medical Ethics
. 2005 Oct;31(10):582–586. doi: 10.1136/jme.2004.010348

Preimplantation HLA typing: having children to save our loved ones

K Devolder 1
PMCID: PMC1734026  PMID: 16199599

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Auerbach A. D. Umbilical cord blood transplants for genetic disease: diagnostic and ethical issues in fetal studies. Blood Cells. 1994;20(2-3):303–309. [PubMed] [Google Scholar]
  2. Benito A. I., Diaz M. A., González-Vicent M., Sevilla J., Madero L. Hematopoietic stem cell transplantation using umbilical cord blood progenitors: review of current clinical results. Bone Marrow Transplant. 2004 Apr;33(7):675–690. doi: 10.1038/sj.bmt.1704405. [DOI] [PubMed] [Google Scholar]
  3. Botkin J. R. Ethical issues and practical problems in preimplantation genetic diagnosis. J Law Med Ethics. 1998 Spring;26(1):17-28, 3. doi: 10.1111/j.1748-720x.1998.tb01902.x. [DOI] [PubMed] [Google Scholar]
  4. Boyle R. J., Savulescu J. Ethics of using preimplantation genetic diagnosis to select a stem cell donor for an existing person. BMJ. 2001 Nov 24;323(7323):1240–1243. doi: 10.1136/bmj.323.7323.1240. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Burgio G. R., Locatelli F. Transplant of bone marrow and cord blood hematopoietic stem cells in pediatric practice, revisited according to the fundamental principles of bioethics. Bone Marrow Transplant. 1997 Jun;19(12):1163–1168. doi: 10.1038/sj.bmt.1700825. [DOI] [PubMed] [Google Scholar]
  6. Fawcett J. T., Arnold F. S. The value of children: theory and method. Represent Res Soc Psychol. 1973 Jan;4(3):23–25. [PubMed] [Google Scholar]
  7. Fortanier C., Kuentz M., Sutton L., Milpied N., Michalet M., Macquart-Moulin G., Faucher C., Le Corroller A. G., Moatti J. P., Blaise D. Healthy sibling donor anxiety and pain during bone marrow or peripheral blood stem cell harvesting for allogeneic transplantation: results of a randomised study. Bone Marrow Transplant. 2002 Jan;29(2):145–149. doi: 10.1038/sj.bmt.1703338. [DOI] [PubMed] [Google Scholar]
  8. Heiney Sue P., Bryant Lisa H., Godder Kamar, Michaels Jill. Preparing children to be bone marrow donors. Oncol Nurs Forum. 2002 Nov-Dec;29(10):1485–1489. doi: 10.1188/02.ONF.1485-1489. [DOI] [PubMed] [Google Scholar]
  9. Orofino Maria Grazia, Argiolu Francesca, Sanna Maria Adele, Rosatelli Maria Cristina, Tuveri Teresa, Scalas Maria Teresa, Badiali Manuela, Cossu Paola, Puddu Rosalba, Lai Maria Eliana. Fetal HLA typing in beta thalassaemia: implications for haemopoietic stem-cell transplantation. Lancet. 2003 Jul 5;362(9377):41–42. doi: 10.1016/S0140-6736(03)13806-8. [DOI] [PubMed] [Google Scholar]
  10. Packman W. Psychosocial impact of pediatric BMT on siblings. Bone Marrow Transplant. 1999 Oct;24(7):701–706. doi: 10.1038/sj.bmt.1701997. [DOI] [PubMed] [Google Scholar]
  11. Pennings G., Schots R., Liebaers I. Ethical considerations on preimplantation genetic diagnosis for HLA typing to match a future child as a donor of haematopoietic stem cells to a sibling. Hum Reprod. 2002 Mar;17(3):534–538. doi: 10.1093/humrep/17.3.534. [DOI] [PubMed] [Google Scholar]
  12. Robertson John A., Kahn Jeffrey P., Wagner John E. Conception to obtain hematopoietic stem cells. Hastings Cent Rep. 2002 May-Jun;32(3):34–40. [PubMed] [Google Scholar]
  13. Shama W. I. The experience and preparation of pediatric sibling bone marrow donors. Soc Work Health Care. 1998;27(1):89–99. doi: 10.1300/J010v27n01_06. [DOI] [PubMed] [Google Scholar]
  14. Shenfield F., Pennings G., Devroey P., Sureau C., Tarlatzis B., Cohen J., ESHRE Ethics Task Force Taskforce 5: preimplantation genetic diagnosis. Hum Reprod. 2003 Mar;18(3):649–651. doi: 10.1093/humrep/deg110. [DOI] [PubMed] [Google Scholar]
  15. Van de Velde H., Georgiou I., De Rycke M., Schots R., Sermon K., Lissens W., Devroey P., Van Steirteghem A., Liebaers I. Novel universal approach for preimplantation genetic diagnosis of beta-thalassaemia in combination with HLA matching of embryos. Hum Reprod. 2004 Jan 29;19(3):700–708. doi: 10.1093/humrep/deh153. [DOI] [PubMed] [Google Scholar]
  16. Verlinsky Y., Rechitsky S., Schoolcraft W., Strom C., Kuliev A. Preimplantation diagnosis for Fanconi anemia combined with HLA matching. JAMA. 2001 Jun 27;285(24):3130–3133. doi: 10.1001/jama.285.24.3130. [DOI] [PubMed] [Google Scholar]
  17. Verlinsky Yury, Kuliev Anver. Current status of preimplantation diagnosis for single gene disorders. Reprod Biomed Online. 2003 Sep;7(2):145–150. doi: 10.1016/s1472-6483(10)61744-0. [DOI] [PubMed] [Google Scholar]
  18. Verlinsky Yury, Rechitsky Svetlana, Sharapova Tatyana, Morris Randy, Taranissi Mohammed, Kuliev Anver. Preimplantation HLA testing. JAMA. 2004 May 5;291(17):2079–2085. doi: 10.1001/jama.291.17.2079. [DOI] [PubMed] [Google Scholar]
  19. Wolf Susan M., Kahn Jeffrey P., Wagner John E. Using preimplantation genetic diagnosis to create a stem cell donor: issues, guidelines & limits. J Law Med Ethics. 2003 Fall;31(3):327–339. doi: 10.1111/j.1748-720x.2003.tb00097.x. [DOI] [PubMed] [Google Scholar]

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