Skip to main content
Infection and Immunity logoLink to Infection and Immunity
. 1995 Sep;63(9):3729–3730. doi: 10.1128/iai.63.9.3729-3730.1995

Spontaneous change from overt to covert infection of Chlamydia pecorum in cycloheximide-treated mouse McCoy cells.

H L Philips 1, M J Clarkson 1
PMCID: PMC173520  PMID: 7642316

Abstract

Some isolates of Chlamydia pecorum from sheep feces failed to produce inclusions on passage in cycloheximide-treated monolayers, but chlamydiae could be recovered several weeks later. Chlamydia psittaci from sheep abortions did not show this phenomenon.

Full Text

The Full Text of this article is available as a PDF (143.6 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Hatch T. P. Competition between Chlamydia psittaci and L cells for host isoleucine pools: a limiting factor in chlamydial multiplication. Infect Immun. 1975 Jul;12(1):211–220. doi: 10.1128/iai.12.1.211-220.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Johnson F. W., Clarkson M. J., Spencer W. N. Direct isolation of the agent of enzootic abortion of ewes (Chlamydia psittaci) in cell cultures. Vet Rec. 1983 Oct 29;113(18):413–414. doi: 10.1136/vr.113.18.413. [DOI] [PubMed] [Google Scholar]
  3. Moulder J. W. Interaction of chlamydiae and host cells in vitro. Microbiol Rev. 1991 Mar;55(1):143–190. doi: 10.1128/mr.55.1.143-190.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Moulder J. W., Levy N. J., Schulman L. P. Persistent infection of mouse fibroblasts (L cells) with Chlamydia psittaci: evidence for a cryptic chlamydial form. Infect Immun. 1980 Dec;30(3):874–883. doi: 10.1128/iai.30.3.874-883.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Moulder J. W., Zeichner S. L., Levy N. J. Association between resistance to superinfection and patterns of surface protein labeling in mouse fibroblasts (L cells) persistently infected with Chlamydia psittaci. Infect Immun. 1982 Mar;35(3):834–839. doi: 10.1128/iai.35.3.834-839.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Perez-Martinez J. A., Storz J. Persistent infection of L cells with an ovine abortion strain of Chlamydia psittaci. Infect Immun. 1985 Nov;50(2):453–458. doi: 10.1128/iai.50.2.453-458.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Rodolakis A., Bernard F., Souriau A., Layachi K., Buzoni-Gatel D. Relationship between virulence of Chlamydia psittaci strains and establishment of persistent infection of McCoy cells. Vet Microbiol. 1989 Jan;19(1):65–73. doi: 10.1016/0378-1135(89)90091-6. [DOI] [PubMed] [Google Scholar]
  8. Schachter J., Storz J., Tarizzo M. L., Bögel K. Chlamydiae as agents of human and animal diseases. Bull World Health Organ. 1973;49(5):443–449. [PMC free article] [PubMed] [Google Scholar]
  9. Spencer W. N., Johnson F. W. Simple transport medium for the isolation of Chlamydia psittaci from clinical material. Vet Rec. 1983 Dec 3;113(23):535–536. [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES