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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1999 May;66(5):672–676. doi: 10.1136/jnnp.66.5.672

Sympathetic contralateral vestibulopathy after unilateral zoster oticus

P Schulz 1, V Arbusow 1, M Strupp 1, M Dieterich 1, W Sautier 1, T Brandt 1
PMCID: PMC1736332  PMID: 10209186

Abstract

A unique case of initially right sided varicella zoster induced Ramsay-Hunt syndrome with complete vestibular loss is reported. The patient subsequently developed deficits of the left vestibule 5 months later. An autoimmune pathogenesis of the left vestibular failure rather than bilateral varicella zoster infection was suggested by the following data: (1) no evidence of vesicular eruptions on the left auricle and the virtual absence of antiviral antibodies after onset of bilateral vestibulopathy; (2) prompt response of the left vestibule to immunosuppressive therapy with corticosteroids; and (3) presence of atypical nervous tissue specific autoantibodies against a 45 kDa protein.



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