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Infection and Immunity logoLink to Infection and Immunity
. 1995 Dec;63(12):4944–4945. doi: 10.1128/iai.63.12.4944-4945.1995

Antioxidant function of melanin in black fungi.

E S Jacobson 1, E Hove 1, H S Emery 1
PMCID: PMC173711  PMID: 7591162

Abstract

1,8-Dihydroxynaphthalene melanin in Wangiella dermatitidis and Alternaria alternata was titrated in vivo with the oxidants permanganate, hypochlorite, and H2O2. Melanized strains neutralized more oxidant and withstood higher concentrations of permanganate and hypochlorite than albino strains did. H2O2 killing required 1,000-fold higher concentrations, and melanin did not protect W. dermatitidis against H2O2.

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Selected References

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