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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 2001 Feb;70(2):259–262. doi: 10.1136/jnnp.70.2.259

Diagnosis of a multifocal B cell lymphoma with preceding demyelinating central nervous system lesions by single voxel proton MR spectroscopy

T Kuhlmann 1, A Schroter 1, P Dechent 1, F Weber 1, H Rustenbeck 1, L Fuzesi 1, W Bruck 1, H Ehrenreich 1, J Frahm 1
PMCID: PMC1737205  PMID: 11160483

Abstract

Single voxel proton magnetic resonance spectroscopy (MRS) provides a rapid non-invasive fingerprint of tissue chemistry. A case history is presented in which a B cell lymphoma with antecedent demyelinating lesions of the CNS was suspected by MRS and confirmed by neuropathological examination and immunoglobulin gene rearrangement.



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