Skip to main content
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 2001 Mar;70(3):340–343. doi: 10.1136/jnnp.70.3.340

Incidence and outcome of subarachnoid haemorrhage: a retrospective population based study

L Pobereskin 1
PMCID: PMC1737269  PMID: 11181855

Abstract

OBJECTIVES—The purpose was to define the incidence and case fatality rates of subarachnoid haemorrhage in the population of Devon and Cornwall.
METHODS—A retrospective population based design was employed with multiple overlapping methods of case ascertainment. A strict definition of subarachnoid haemorrhage was used. Age and sex specific incidence rates and relative risks for death at different time intervals are calculated.
RESULTS—Eight hundred cases of first ever subarachnoid haemorrhage were identified; 77% of cases were verified by CT, 22% by necropsy, and 1% by lumbar puncture. The incidence rates are higher than those previously reported in the United Kingdom. The age standardised incidence rate (/100 000 person-years) for females was 11.9 (95% confidence interval (95% CI) 9.5-15.0), for males 7.4 (5.4-10.0), and the total rate was 9.7 (7.5-12.6). The case fatality rates at 24 hours, 1 week, and 30 days were 21 (18-24)%, 37 (33-41)%, and 44 (40-49)% respectively. The relative risk for death at 30days for those over 60 years:under 60 years was 2.95 (2.18-3.97).
CONCLUSION—The incidence of subarachnoid haemorrhage in the United Kingdom is higher than previously reported. Three quarters of the mortality occurs within 3days.



Full Text

The Full Text of this article is available as a PDF (104.6 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Awad I. A., Carter L. P., Spetzler R. F., Medina M., Williams F. C., Jr Clinical vasospasm after subarachnoid hemorrhage: response to hypervolemic hemodilution and arterial hypertension. Stroke. 1987 Mar-Apr;18(2):365–372. doi: 10.1161/01.str.18.2.365. [DOI] [PubMed] [Google Scholar]
  2. Bamford J., Sandercock P., Dennis M., Burn J., Warlow C. A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project--1981-86. 2. Incidence, case fatality rates and overall outcome at one year of cerebral infarction, primary intracerebral and subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry. 1990 Jan;53(1):16–22. doi: 10.1136/jnnp.53.1.16. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Brewis M., Poskanzer D. C., Rolland C., Miller H. Neurological disease in an English city. Acta Neurol Scand. 1966;42(Suppl):1–89. [PubMed] [Google Scholar]
  4. Crawford M. D., Sarner M. Ruptured intracranial aneurysm. Community study. Lancet. 1965 Dec 18;2(7425):1254–1257. doi: 10.1016/s0140-6736(65)92277-4. [DOI] [PubMed] [Google Scholar]
  5. Harmsen P., Tsipogianni A., Wilhelmsen L. Stroke incidence rates were unchanged, while fatality rates declined, during 1971-1987 in Göteborg, Sweden. Stroke. 1992 Oct;23(10):1410–1415. doi: 10.1161/01.str.23.10.1410. [DOI] [PubMed] [Google Scholar]
  6. Hop J. W., Rinkel G. J., Algra A., van Gijn J. Case-fatality rates and functional outcome after subarachnoid hemorrhage: a systematic review. Stroke. 1997 Mar;28(3):660–664. doi: 10.1161/01.str.28.3.660. [DOI] [PubMed] [Google Scholar]
  7. Linn F. H., Rinkel G. J., Algra A., van Gijn J. Incidence of subarachnoid hemorrhage: role of region, year, and rate of computed tomography: a meta-analysis. Stroke. 1996 Apr;27(4):625–629. doi: 10.1161/01.str.27.4.625. [DOI] [PubMed] [Google Scholar]
  8. Malmgren R., Warlow C., Bamford J., Sandercock P. Geographical and secular trends in stroke incidence. Lancet. 1987 Nov 21;2(8569):1196–1200. doi: 10.1016/s0140-6736(87)91331-6. [DOI] [PubMed] [Google Scholar]
  9. Ostbye T., Levy A. R., Mayo N. E. Hospitalization and case-fatality rates for subarachnoid hemorrhage in Canada from 1982 through 1991. The Canadian Collaborative Study Group of Stroke Hospitalizations. Stroke. 1997 Apr;28(4):793–798. doi: 10.1161/01.str.28.4.793. [DOI] [PubMed] [Google Scholar]
  10. Pickard J. D., Murray G. D., Illingworth R., Shaw M. D., Teasdale G. M., Foy P. M., Humphrey P. R., Lang D. A., Nelson R., Richards P. Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial. BMJ. 1989 Mar 11;298(6674):636–642. doi: 10.1136/bmj.298.6674.636. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Sudlow C. L., Warlow C. P. Comparable studies of the incidence of stroke and its pathological types: results from an international collaboration. International Stroke Incidence Collaboration. Stroke. 1997 Mar;28(3):491–499. doi: 10.1161/01.str.28.3.491. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES