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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 2002 Sep;73(3):281–288. doi: 10.1136/jnnp.73.3.281

Long term psychosocial outcomes after mild head injury in early childhood

A McKinlay 1, J Dalrymple-Alford 1, L Horwood 1, D Fergusson 1
PMCID: PMC1738032  PMID: 12185159

Abstract

Objectives: The question of whether any adverse cognitive or psychosocial outcomes occur after mild head injury in early childhood has evoked considerable controversy. This study examined mild head injury before age 10 and potential differences in late childhood/early adolescence as a function of severity of mild injury and age at injury.

Methods: A fully prospective longitudinal design tracked a large birth cohort of children. Confirmed cases of mild head injury before age 10 were divided on the basis of outpatient medical attention (n=64–84) or inpatient observation (hospital overnight; n=26–28 ) and compared with the non-injured remainder of the cohort (reference group; n=613–807). A range of pre-injury and post-injury child and family characteristics were used to control for any potential confounds. Outcome after injury before and after age 5 was also assessed.

Results: After accounting for several demographic, family, and pre-injury characteristics, the inpatient but not the outpatient group displayed increased hyperactivity/inattention and conduct disorder between ages 10 to 13, as rated by both mothers and teachers. Psychosocial deficits were more prevalent in the inpatient subgroup injured before age 5. No clear effects were evident for various cognitive/academic measures, irrespective of severity of mild injury or age at injury.

Conclusions: Most cases of mild head injury in young children do not produce any adverse effects, but long term problems in psychosocial function are possible in more severe cases, perhaps especially when this event occurs during the preschool years. The view that all mild head injuries in children are benign events requires revision and more objective measures are required to identify cases at risk.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson V. A., Morse S. A., Klug G., Catroppa C., Haritou F., Rosenfeld J., Pentland L. Predicting recovery from head injury in young children: a prospective analysis. J Int Neuropsychol Soc. 1997 Nov;3(6):568–580. [PubMed] [Google Scholar]
  2. Andrews T. K., Rose F. D., Johnson D. A. Social and behavioural effects of traumatic brain injury in children. Brain Inj. 1998 Feb;12(2):133–138. doi: 10.1080/026990598122755. [DOI] [PubMed] [Google Scholar]
  3. Asarnow R. F., Satz P., Light R., Lewis R., Neumann E. Behavior problems and adaptive functioning in children with mild and severe closed head injury. J Pediatr Psychol. 1991 Oct;16(5):543–555. doi: 10.1093/jpepsy/16.5.543. [DOI] [PubMed] [Google Scholar]
  4. Beers S. R. Cognitive effects of mild head injury in children and adolescents. Neuropsychol Rev. 1992 Dec;3(4):281–320. doi: 10.1007/BF01108414. [DOI] [PubMed] [Google Scholar]
  5. Bijur P. E., Haslum M., Golding J. Cognitive and behavioral sequelae of mild head injury in children. Pediatrics. 1990 Sep;86(3):337–344. [PubMed] [Google Scholar]
  6. Bijur P. E., Haslum M., Golding J. Cognitive outcomes of multiple mild head injuries in children. J Dev Behav Pediatr. 1996 Jun;17(3):143–148. [PubMed] [Google Scholar]
  7. Brown G., Chadwick O., Shaffer D., Rutter M., Traub M. A prospective study of children with head injuries: III. Psychiatric sequelae. Psychol Med. 1981 Feb;11(1):63–78. doi: 10.1017/s0033291700053289. [DOI] [PubMed] [Google Scholar]
  8. Cantwell D. P. Attention deficit disorder: a review of the past 10 years. J Am Acad Child Adolesc Psychiatry. 1996 Aug;35(8):978–987. doi: 10.1097/00004583-199608000-00008. [DOI] [PubMed] [Google Scholar]
  9. Casey R., Ludwig S., McCormick M. C. Morbidity following minor head trauma in children. Pediatrics. 1986 Sep;78(3):497–502. [PubMed] [Google Scholar]
  10. Chadwick O., Rutter M., Brown G., Shaffer D., Traub M. U. A prospective study of children with head injuries: II. Cognitive sequelae. Psychol Med. 1981 Feb;11(1):49–61. doi: 10.1017/s0033291700053277. [DOI] [PubMed] [Google Scholar]
  11. Costeff H., Abraham E., Brenner T., Horowitz I., Apter N., Sadan N., Najenson T. Late neuropsychologic status after childhood head trauma. Brain Dev. 1988;10(6):371–374. doi: 10.1016/s0387-7604(88)80095-0. [DOI] [PubMed] [Google Scholar]
  12. Donders J. Premorbid behavioral and psychosocial adjustment of children with traumatic brain injury. J Abnorm Child Psychol. 1992 Jun;20(3):233–246. doi: 10.1007/BF00916690. [DOI] [PubMed] [Google Scholar]
  13. Fay G. C., Jaffe K. M., Polissar N. L., Liao S., Martin K. M., Shurtleff H. A., Rivara J. M., Winn H. R. Mild pediatric traumatic brain injury: a cohort study. Arch Phys Med Rehabil. 1993 Sep;74(9):895–901. [PubMed] [Google Scholar]
  14. Fergusson D. M., Horwood L. J., Lloyd M. Confirmatory factor models of attention deficit and conduct disorder. J Child Psychol Psychiatry. 1991 Jan;32(2):257–274. doi: 10.1111/j.1469-7610.1991.tb00305.x. [DOI] [PubMed] [Google Scholar]
  15. Fergusson D. M., Horwood L. J., Lynskey M. T. Prevalence and comorbidity of DSM-III-R diagnoses in a birth cohort of 15 year olds. J Am Acad Child Adolesc Psychiatry. 1993 Nov;32(6):1127–1134. doi: 10.1097/00004583-199311000-00004. [DOI] [PubMed] [Google Scholar]
  16. Fergusson D. M., Horwood L. J. The effects of lead levels on the growth of word recognition in middle childhood. Int J Epidemiol. 1993 Oct;22(5):891–897. doi: 10.1093/ije/22.5.891. [DOI] [PubMed] [Google Scholar]
  17. Fergusson D. M., Lynskey M. T., Horwood L. J. Attentional difficulties in middle childhood and psychosocial outcomes in young adulthood. J Child Psychol Psychiatry. 1997 Sep;38(6):633–644. doi: 10.1111/j.1469-7610.1997.tb01690.x. [DOI] [PubMed] [Google Scholar]
  18. Fergusson D. M., Lynskey M. T., Horwood L. J. Factors associated with continuity and changes in disruptive behavior patterns between childhood and adolescence. J Abnorm Child Psychol. 1996 Oct;24(5):533–553. doi: 10.1007/BF01670099. [DOI] [PubMed] [Google Scholar]
  19. Fletcher J. M., Ewing-Cobbs L., Miner M. E., Levin H. S., Eisenberg H. M. Behavioral changes after closed head injury in children. J Consult Clin Psychol. 1990 Feb;58(1):93–98. doi: 10.1037//0022-006x.58.1.93. [DOI] [PubMed] [Google Scholar]
  20. Fletcher J. M., Levin H. S., Lachar D., Kusnerik L., Harward H., Mendelsohn D., Lilly M. A. Behavioral outcomes after pediatric closed head injury: relationships with age, severity, and lesion size. J Child Neurol. 1996 Jul;11(4):283–290. doi: 10.1177/088307389601100404. [DOI] [PubMed] [Google Scholar]
  21. Gronwall D., Wrightson P., McGinn V. Effect of mild head injury during the preschool years. J Int Neuropsychol Soc. 1997 Nov;3(6):592–597. [PubMed] [Google Scholar]
  22. Guerrero J. L., Thurman D. J., Sniezek J. E. Emergency department visits associated with traumatic brain injury: United States, 1995-1996. Brain Inj. 2000 Feb;14(2):181–186. [PubMed] [Google Scholar]
  23. Hart K., Faust D. Prediction of the effects of mild head injury: a message about the Kennard Principle. J Clin Psychol. 1988 Sep;44(5):780–782. doi: 10.1002/1097-4679(198809)44:5<780::aid-jclp2270440519>3.0.co;2-1. [DOI] [PubMed] [Google Scholar]
  24. Herrmann M., Curio N., Jost S., Grubich C., Ebert A. D., Fork M. L., Synowitz H. Release of biochemical markers of damage to neuronal and glial brain tissue is associated with short and long term neuropsychological outcome after traumatic brain injury. J Neurol Neurosurg Psychiatry. 2001 Jan;70(1):95–100. doi: 10.1136/jnnp.70.1.95. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Horowitz I., Costeff H., Sadan N., Abraham E., Geyer S., Najenson T. Childhood head injuries in Israel: epidemiology and outcome. Int Rehabil Med. 1983;5(1):32–36. doi: 10.3109/09638288309166936. [DOI] [PubMed] [Google Scholar]
  26. Jordan F. M., Cannon A., Murdoch B. E. Language abilities of mildly closed head injured (CHI) children 10 years post-injury. Brain Inj. 1992 Jan-Feb;6(1):39–44. doi: 10.3109/02699059209008120. [DOI] [PubMed] [Google Scholar]
  27. Kant R., Smith-Seemiller L., Isaac G., Duffy J. Tc-HMPAO SPECT in persistent post-concussion syndrome after mild head injury: comparison with MRI/CT. Brain Inj. 1997 Feb;11(2):115–124. doi: 10.1080/026990597123700. [DOI] [PubMed] [Google Scholar]
  28. Kibby M. Y., Long C. J. Minor head injury: attempts at clarifying the confusion. Brain Inj. 1996 Mar;10(3):159–186. doi: 10.1080/026990596124494. [DOI] [PubMed] [Google Scholar]
  29. Kinsella G., Ong B., Murtagh D., Prior M., Sawyer M. The role of the family for behavioral outcome in children and adolescents following traumatic brain injury. J Consult Clin Psychol. 1999 Feb;67(1):116–123. doi: 10.1037//0022-006x.67.1.116. [DOI] [PubMed] [Google Scholar]
  30. Klonoff H., Clark C., Klonoff P. S. Long-term outcome of head injuries: a 23 year follow up study of children with head injuries. J Neurol Neurosurg Psychiatry. 1993 Apr;56(4):410–415. doi: 10.1136/jnnp.56.4.410. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Klonoff H., Low M. D., Clark C. Head injuries in children: a prospective five year follow-up. J Neurol Neurosurg Psychiatry. 1977 Dec;40(12):1211–1219. doi: 10.1136/jnnp.40.12.1211. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Knights R. M., Ivan L. P., Ventureyra E. C., Bentivoglio C., Stoddart C., Winogron W., Bawden H. N. The effects of head injury in children on neuropsychological and behavioural functioning. Brain Inj. 1991 Oct-Dec;5(4):339–351. doi: 10.3109/02699059109008107. [DOI] [PubMed] [Google Scholar]
  33. Kraus J. F., Fife D., Conroy C. Pediatric brain injuries: the nature, clinical course, and early outcomes in a defined United States' population. Pediatrics. 1987 Apr;79(4):501–507. [PubMed] [Google Scholar]
  34. Levin H. S., Williams D. H., Eisenberg H. M., High W. M., Jr, Guinto F. C., Jr Serial MRI and neurobehavioural findings after mild to moderate closed head injury. J Neurol Neurosurg Psychiatry. 1992 Apr;55(4):255–262. doi: 10.1136/jnnp.55.4.255. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Light R., Asarnow R., Satz P., Zaucha K., McCleary C., Lewis R. Mild closed-head injury in children and adolescents: behavior problems and academic outcomes. J Consult Clin Psychol. 1998 Dec;66(6):1023–1029. doi: 10.1037//0022-006x.66.6.1023. [DOI] [PubMed] [Google Scholar]
  36. Max J. E., Lindgren S. D., Knutson C., Pearson C. S., Ihrig D., Welborn A. Child and adolescent traumatic brain injury: correlates of disruptive behaviour disorders. Brain Inj. 1998 Jan;12(1):41–52. doi: 10.1080/026990598122845. [DOI] [PubMed] [Google Scholar]
  37. Max J. E., Robin D. A., Lindgren S. D., Smith W. L., Jr, Sato Y., Mattheis P. J., Stierwalt J. A., Castillo C. S. Traumatic brain injury in children and adolescents: psychiatric disorders at two years. J Am Acad Child Adolesc Psychiatry. 1997 Sep;36(9):1278–1285. doi: 10.1097/00004583-199709000-00021. [DOI] [PubMed] [Google Scholar]
  38. Mittl R. L., Grossman R. I., Hiehle J. F., Hurst R. W., Kauder D. R., Gennarelli T. A., Alburger G. W. Prevalence of MR evidence of diffuse axonal injury in patients with mild head injury and normal head CT findings. AJNR Am J Neuroradiol. 1994 Sep;15(8):1583–1589. [PMC free article] [PubMed] [Google Scholar]
  39. Pelco L., Sawyer M., Duffield G., Prior M., Kinsella G. Premorbid emotional and behavioural adjustment in children with mild head injuries. Brain Inj. 1992 Jan-Feb;6(1):29–37. doi: 10.3109/02699059209008119. [DOI] [PubMed] [Google Scholar]
  40. Perrin E. C., Stein R. E., Drotar D. Cautions in using the Child Behavior Checklist: observations based on research about children with a chronic illness. J Pediatr Psychol. 1991 Aug;16(4):411–421. doi: 10.1093/jpepsy/16.4.411. [DOI] [PubMed] [Google Scholar]
  41. Ponsford J., Willmott C., Rothwell A., Cameron P., Ayton G., Nelms R., Curran C., Ng K. T. Cognitive and behavioral outcome following mild traumatic head injury in children. J Head Trauma Rehabil. 1999 Aug;14(4):360–372. doi: 10.1097/00001199-199908000-00005. [DOI] [PubMed] [Google Scholar]
  42. Reitman D., Hummel R., Franz D. Z., Gross A. M. A review of methods and instruments for assessing externalizing disorders: theoretical and practical considerations in rendering a diagnosis. Clin Psychol Rev. 1998 Aug;18(5):555–584. doi: 10.1016/s0272-7358(98)00003-8. [DOI] [PubMed] [Google Scholar]
  43. Satz P., Zaucha K., McCleary C., Light R., Asarnow R., Becker D. Mild head injury in children and adolescents: a review of studies (1970-1995). Psychol Bull. 1997 Sep;122(2):107–131. doi: 10.1037/0033-2909.122.2.107. [DOI] [PubMed] [Google Scholar]
  44. Schutzman S. A., Barnes P., Duhaime A. C., Greenes D., Homer C., Jaffe D., Lewis R. J., Luerssen T. G., Schunk J. Evaluation and management of children younger than two years old with apparently minor head trauma: proposed guidelines. Pediatrics. 2001 May;107(5):983–993. doi: 10.1542/peds.107.5.983. [DOI] [PubMed] [Google Scholar]
  45. Stiell I. G., Wells G. A., Vandemheen K., Clement C., Lesiuk H., Laupacis A., McKnight R. D., Verbeek R., Brison R., Cass D. The Canadian CT Head Rule for patients with minor head injury. Lancet. 2001 May 5;357(9266):1391–1396. doi: 10.1016/s0140-6736(00)04561-x. [DOI] [PubMed] [Google Scholar]
  46. Taylor H. G., Alden J. Age-related differences in outcomes following childhood brain insults: an introduction and overview. J Int Neuropsychol Soc. 1997 Nov;3(6):555–567. [PubMed] [Google Scholar]
  47. Teasdale G., Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet. 1974 Jul 13;2(7872):81–84. doi: 10.1016/s0140-6736(74)91639-0. [DOI] [PubMed] [Google Scholar]
  48. Tompkins C. A., Holland A. L., Ratcliff G., Costello A., Leahy L. F., Cowell V. Predicting cognitive recovery from closed head-injury in children and adolescents. Brain Cogn. 1990 May;13(1):86–97. doi: 10.1016/0278-2626(90)90042-m. [DOI] [PubMed] [Google Scholar]
  49. Voller B., Auff E., Schnider P., Aichner F. To do or not to do? Magnetic resonance imaging in mild traumatic brain injury. Brain Inj. 2001 Feb;15(2):107–115. doi: 10.1080/026990501458344. [DOI] [PubMed] [Google Scholar]
  50. Voller B., Benke T., Benedetto K., Schnider P., Auff E., Aichner F. Neuropsychological, MRI and EEG findings after very mild traumatic brain injury. Brain Inj. 1999 Oct;13(10):821–827. doi: 10.1080/026990599121214. [DOI] [PubMed] [Google Scholar]
  51. Webb C., Rose F. D., Johnson D. A., Attree E. A. Age and recovery from brain injury: clinical opinions and experimental evidence. Brain Inj. 1996 Apr;10(4):303–310. doi: 10.1080/026990596124476. [DOI] [PubMed] [Google Scholar]
  52. Wrightson P., McGinn V., Gronwall D. Mild head injury in preschool children: evidence that it can be associated with a persisting cognitive defect. J Neurol Neurosurg Psychiatry. 1995 Oct;59(4):375–380. doi: 10.1136/jnnp.59.4.375. [DOI] [PMC free article] [PubMed] [Google Scholar]

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