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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 2004 Oct;75(10):1489–1491. doi: 10.1136/jnnp.2003.028118

Massive reduction of tumour load and normalisation of hyperprolactinaemia after high dose cabergoline in metastasised prolactinoma causing thoracic syringomyelia

S H M van Uum 1, N van Alfen 1, P Wesseling 1, E van Lindert 1, G Pieters 1, P Nooijen 1, A Hermus 1
PMCID: PMC1738774  PMID: 15377706

Abstract

On administration of high dose cabergoline, 0.5 mg twice a day orally, the plasma prolactin levels decreased within one month and then normalised within 26 months. Tumour load reduced considerably but unfortunately, her signs and symptoms did not improve. This case illustrates that a high dose dopamine agonist might be an important therapeutic option in patients with a metastasised prolactinoma.

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