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. 1996 Mar;64(3):1078–1080. doi: 10.1128/iai.64.3.1078-1080.1996

Increased numbers of interleukin-12-producing cells in human tuberculosis.

M E Munk 1, P Mayer 1, P Anding 1, K Feldmann 1, S H Kaufmann 1
PMCID: PMC173886  PMID: 8641765

Abstract

Numbers of interleukin-12 (IL-12) producing cells were quantitated in the peripheral blood of healthy donors and tuberculosis patients by the ELISPOT assay. We observed that (i) stimulation with mycobacteria increases numbers of IL-12 producers from healthy donors and (ii) tuberculosis patients have larger numbers of IL-12 producers than healthy donors. Our data emphasize the importance of Il-12 in immunity to tuberculosis.

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Selected References

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