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. 1996 Apr;64(4):1480–1483. doi: 10.1128/iai.64.4.1480-1483.1996

CD36 and intercellular adhesion molecule 1 mediate adhesion of developing Plasmodium falciparum gametocytes.

N J Rogers 1, O Daramola 1, G A Targett 1, B S Hall 1
PMCID: PMC173949  PMID: 8606124

Abstract

Plasmodium falciparum trophozoite-infected erythrocytes adhere to the amelanotic melanoma C32 cell line in vitro. Here we demonstrate for the first time that immature gametocyte-infected erythrocytes also adhere to C32 cells, albeit at lower levels than trophozoites. However, anti-CD36 and anti-intercellular adhesion molecule 1 antibodies inhibit asexual and gametocyte adhesion by comparable percentages, suggesting a common dependency for binding to these cellular receptors.

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Selected References

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