Skip to main content
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 2005 Jul;76(7):977–983. doi: 10.1136/jnnp.2004.039974

Surgical management of tuberculum sellae meningiomas: involvement of the optic canal and visual outcome

U Schick 1, W Hassler 1
PMCID: PMC1739719  PMID: 15965205

Abstract

Objective: To present a large series of surgically treated tuberculum sellae meningiomas with particular regard to involvement of the optic canal and visual outcome.

Methods: A retrospective analysis was done on 53 patients (40 female) with meningiomas originating from the tuberculum sellae who underwent surgery between 1991 and 2002. The standard surgical approach consisted of pterional craniotomy. Sixteen meningiomas extended posteriorly onto the diaphragma sella, 29 anteriorly to the planum sphenoidale, and 19 to the anterior clinoid process. Thirty seven tumours involved the optic canal, three bilaterally. Follow up ranged from 6 to 108 months (mean 29.9 months).

Results: Total macroscopic resection was achieved in 48 patients. Median tumour size was 2.6 cm. Postoperatively, visual acuity improved in 20 patients and deteriorated in seven. Preoperative and postoperative visual acuity worsened with increasing duration of preoperative symptoms and with increasing age. Extension into the intraconal space was a negative predictor. However, tumour size did not influence visual acuity. Recurrence occurred in two cases (21 and 69 months postoperatively). Two patients died from causes unrelated to the tumour.

Conclusions: In the majority of patients with tuberculum sellae meningiomas, total resection may be achieved through a pterional approach with minimal complications.

Full Text

The Full Text of this article is available as a PDF (302.0 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Al-Mefty O., Holoubi A., Rifai A., Fox J. L. Microsurgical removal of suprasellar meningiomas. Neurosurgery. 1985 Mar;16(3):364–372. doi: 10.1227/00006123-198503000-00014. [DOI] [PubMed] [Google Scholar]
  2. Andrews B. T., Wilson C. B. Suprasellar meningiomas: the effect of tumor location on postoperative visual outcome. J Neurosurg. 1988 Oct;69(4):523–528. doi: 10.3171/jns.1988.69.4.0523. [DOI] [PubMed] [Google Scholar]
  3. Arai H., Sato K., Okuda, Miyajima M., Hishii M., Nakanishi H., Ishii H. Transcranial transsphenoidal approach for tuberculum sellae meningiomas. Acta Neurochir (Wien) 2000;142(7):751–757. doi: 10.1007/s007010070089. [DOI] [PubMed] [Google Scholar]
  4. Becker Gerd, Jeremic Branislav, Pitz Susanne, Buchgeister Markus, Wilhelm Helmut, Schiefer Ulrich, Paulsen Frank, Zrenner Eberhart, Bamberg Michael. Stereotactic fractionated radiotherapy in patients with optic nerve sheath meningioma. Int J Radiat Oncol Biol Phys. 2002 Dec 1;54(5):1422–1429. doi: 10.1016/s0360-3016(02)03753-7. [DOI] [PubMed] [Google Scholar]
  5. Chang J. H., Chang J. W., Choi J. Y., Park Y. G., Chung S. S. Complications after gamma knife radiosurgery for benign meningiomas. J Neurol Neurosurg Psychiatry. 2003 Feb;74(2):226–230. doi: 10.1136/jnnp.74.2.226. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Cornu P., Chatellier G., Dagreou F., Clemenceau S., Foncin J. F., Rivierez M., Philippon J. Intracranial meningiomas in elderly patients. Postoperative morbidity and mortality. Factors predictive of outcome. Acta Neurochir (Wien) 1990;102(3-4):98–102. doi: 10.1007/BF01405421. [DOI] [PubMed] [Google Scholar]
  7. DeMonte F. Surgical treatment of anterior basal meningiomas. J Neurooncol. 1996 Sep;29(3):239–248. doi: 10.1007/BF00165654. [DOI] [PubMed] [Google Scholar]
  8. Debus J., Wuendrich M., Pirzkall A., Hoess A., Schlegel W., Zuna I., Engenhart-Cabillic R., Wannenmacher M. High efficacy of fractionated stereotactic radiotherapy of large base-of-skull meningiomas: long-term results. J Clin Oncol. 2001 Aug 1;19(15):3547–3553. doi: 10.1200/JCO.2001.19.15.3547. [DOI] [PubMed] [Google Scholar]
  9. Fahlbusch Rudolf, Schott Werner. Pterional surgery of meningiomas of the tuberculum sellae and planum sphenoidale: surgical results with special consideration of ophthalmological and endocrinological outcomes. J Neurosurg. 2002 Feb;96(2):235–243. doi: 10.3171/jns.2002.96.2.0235. [DOI] [PubMed] [Google Scholar]
  10. Hassler W., Eggert H. R. Extradural and intradural microsurgical approaches to lesions of the optic canal and the superior orbital fissure. Acta Neurochir (Wien) 1985;74(3-4):87–93. doi: 10.1007/BF01418794. [DOI] [PubMed] [Google Scholar]
  11. Lee J. H., Jeun S. S., Evans J., Kosmorsky G. Surgical management of clinoidal meningiomas. Neurosurgery. 2001 May;48(5):1012–1021. doi: 10.1097/00006123-200105000-00009. [DOI] [PubMed] [Google Scholar]
  12. Mathiesen T., Lindquist C., Kihlström L., Karlsson B. Recurrence of cranial base meningiomas. Neurosurgery. 1996 Jul;39(1):2–9. doi: 10.1097/00006123-199607000-00002. [DOI] [PubMed] [Google Scholar]
  13. McAdam J. G., Templeton J. L., Nixon J. R. Isolated fractures of the first ribs--an indication of major cervicomediastinal injury. Injury. 1986 Jul;17(4):226–227. doi: 10.1016/0020-1383(86)90224-x. [DOI] [PubMed] [Google Scholar]
  14. Mendenhall William M., Morris Christopher G., Amdur Robert J., Foote Kelly D., Friedman William A. Radiotherapy alone or after subtotal resection for benign skull base meningiomas. Cancer. 2003 Oct 1;98(7):1473–1482. doi: 10.1002/cncr.11645. [DOI] [PubMed] [Google Scholar]
  15. Mourits Maarten Ph., van der Sprenkel Jan Willem Berkelbach. Orbital meningioma, the Utrecht experience. Orbit. 2001 Mar;20(1):25–33. doi: 10.1076/orbi.20.1.25.2640. [DOI] [PubMed] [Google Scholar]
  16. Ohta K., Yasuo K., Morikawa M., Nagashima T., Tamaki N. Treatment of tuberculum sellae meningiomas:a long-term follow-up study. J Clin Neurosci. 2001 May;8 (Suppl 1):26–31. doi: 10.1054/jocn.2001.0873. [DOI] [PubMed] [Google Scholar]
  17. Pendl G., Eustacchio S., Unger F. Radiosurgery as alternative treatment for skull base meningiomas. J Clin Neurosci. 2001 May;8 (Suppl 1):12–14. doi: 10.1054/jocn.2001.0869. [DOI] [PubMed] [Google Scholar]
  18. Raco A., Bristot R., Domenicucci M., Cantore G. Meningiomas of the tuberculum sellae. Our experience in 69 cases surgically treated between 1973 and 1993. J Neurosurg Sci. 1999 Dec;43(4):253–262. [PubMed] [Google Scholar]
  19. Shimano H., Nagasawa S., Kawabata S., Ogawa R., Ohta T. Surgical strategy for meningioma extension into the optic canal. Neurol Med Chir (Tokyo) 2000 Sep;40(9):447–452. doi: 10.2176/nmc.40.447. [DOI] [PubMed] [Google Scholar]
  20. Symon L., Rosenstein J. Surgical management of suprasellar meningioma. Part 1: The influence of tumor size, duration of symptoms, and microsurgery on surgical outcome in 101 consecutive cases. J Neurosurg. 1984 Oct;61(4):633–641. doi: 10.3171/jns.1984.61.4.0633. [DOI] [PubMed] [Google Scholar]
  21. Vikramaditya, Pritty P. Two cases of isolated first rib fracture. Emerg Med J. 2001 Nov;18(6):498–499. doi: 10.1136/emj.18.6.498. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Villavicencio A. T., Black P. M., Shrieve D. C., Fallon M. P., Alexander E., Loeffler J. S. Linac radiosurgery for skull base meningiomas. Acta Neurochir (Wien) 2001 Nov;143(11):1141–1152. doi: 10.1007/s007010100005. [DOI] [PubMed] [Google Scholar]
  23. Zevgaridis D., Medele R. J., Müller A., Hischa A. C., Steiger H. J. Meningiomas of the sellar region presenting with visual impairment: impact of various prognostic factors on surgical outcome in 62 patients. Acta Neurochir (Wien) 2001;143(5):471–476. doi: 10.1007/s007010170076. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES