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. 2001 Aug;58(8):496–503. doi: 10.1136/oem.58.8.496

Respiratory health effects from exposure to carbon black: results of the phase 2 and 3 cross sectional studies in the European carbon black manufacturing industry

K Gardiner 1, M van Tongeren 1, M Harrington 1
PMCID: PMC1740179  PMID: 11452043

Abstract

OBJECTIVES—To assess respiratory morbidity over several cross sectional phases in the European carbon black manufacturing industry.
METHODS—Participants completed an amended (and translated) MRC respiratory morbidity questionnaire with additional questions on previous exposures, job history, etc, and spirometry traces in each phase. Concurrent with the health outcome measures, personal exposure to inhalable dust was measured.
RESULTS—Percentage participation rose from 90% in phase 2 (19 factories) to 95% in phase 3 (16 factories). Exposure dropped slightly between the 2 and 3 phases; as did the prevalence of reporting symptoms. Percentage of predicted lung function volumes exceeded 100% for forced expired volume in 1 second (FEV1) and forced vital capacity (FVC), whereas forced mid-expiratory flow (FEF25%-75%) and FEV1/FVC ratio were below 100% in both phases. The multiple linear and logistic regressions showed that carbon black had a significant effect on lung function and on most respiratory symptoms, respectively.
CONCLUSION—Both current and cumulative exposure to carbon black have a deleterious effect on respiratory morbidity. Due to the drop in exposure between phases 2 and 3, recent exposures seem to have less of an impact on the respiratory morbidity in the workers in phase 3 than those in phase 2.


Keywords: carbon black; respiratory morbidity; spirometry

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Selected References

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  1. Attfield M. D., Hewett P. Exact expressions for the bias and variance of estimators of the mean of a lognormal distribution. Am Ind Hyg Assoc J. 1992 Jul;53(7):432–435. doi: 10.1080/15298669291359906. [DOI] [PubMed] [Google Scholar]
  2. Bradshaw L. M., Fishwick D., Slater T., Pearce N. Chronic bronchitis, work related respiratory symptoms, and pulmonary function in welders in New Zealand. Occup Environ Med. 1998 Mar;55(3):150–154. doi: 10.1136/oem.55.3.150. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Erkinjuntti-Pekkanen R., Slater T., Cheng S., Fishwick D., Bradshaw L., Kimbell-Dunn M., Dronfield L., Pearce N. Two year follow up of pulmonary function values among welders in New Zealand. Occup Environ Med. 1999 May;56(5):328–333. doi: 10.1136/oem.56.5.328. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Gardiner K., Calvert I. A., van Tongeren M. J., Harrington J. M. Occupational exposure to carbon black in its manufacture: data from 1987 to 1992. Ann Occup Hyg. 1996 Feb;40(1):65–77. doi: 10.1016/0003-4878(95)00059-3. [DOI] [PubMed] [Google Scholar]
  5. Gardiner K. Effects on respiratory morbidity of occupational exposure to carbon black: a review. Arch Environ Health. 1995 Jan-Feb;50(1):44–60. doi: 10.1080/00039896.1995.9955012. [DOI] [PubMed] [Google Scholar]
  6. Gardiner K., Hale K. A., Calvert I. A., Rice C., Harrington J. M. The suitability of the urinary metabolite 1-hydroxypyrene as an index of poly nuclear aromatic hydrocarbon bioavailability from workers exposed to carbon black. Ann Occup Hyg. 1992 Dec;36(6):681–688. doi: 10.1093/annhyg/36.6.681. [DOI] [PubMed] [Google Scholar]
  7. Gardiner K., Trethowan N. W., Harrington J. M., Rossiter C. E., Calvert I. A. Respiratory health effects of carbon black: a survey of European carbon black workers. Br J Ind Med. 1993 Dec;50(12):1082–1096. doi: 10.1136/oem.50.12.1082. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Küpper H. U., Breitstadt R., Ulmer W. T. Effects on the lung function of exposure to carbon black dusts. Results of a study carried out on 677 members of staff of the DEGUSSA factory in Kalscheuren/Germany. Int Arch Occup Environ Health. 1996;68(6):478–483. doi: 10.1007/BF00377873. [DOI] [PubMed] [Google Scholar]
  9. Love R. G., Waclawski E. R., Maclaren W. M., Wetherill G. Z., Groat S. K., Porteous R. H., Soutar C. A. Risks of respiratory disease in the heavy clay industry. Occup Environ Med. 1999 Feb;56(2):124–133. doi: 10.1136/oem.56.2.124. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Mark D., Vincent J. H. A new personal sampler for airborne total dust in workplaces. Ann Occup Hyg. 1986;30(1):89–102. doi: 10.1093/annhyg/30.1.89. [DOI] [PubMed] [Google Scholar]
  11. Quanjer P. H., Tammeling G. J., Cotes J. E., Pedersen O. F., Peslin R., Yernault J. C. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl. 1993 Mar;16:5–40. [PubMed] [Google Scholar]
  12. Rappaport S. M. Assessment of long-term exposures to toxic substances in air. Ann Occup Hyg. 1991 Feb;35(1):61–121. doi: 10.1093/annhyg/35.1.61. [DOI] [PubMed] [Google Scholar]
  13. Roca J., Burgos F., Sunyer J., Saez M., Chinn S., Antó J. M., Rodríguez-Roisin R., Quanjer P. H., Nowak D., Burney P. References values for forced spirometry. Group of the European Community Respiratory Health Survey. Eur Respir J. 1998 Jun;11(6):1354–1362. doi: 10.1183/09031936.98.11061354. [DOI] [PubMed] [Google Scholar]
  14. Simpson J. C., Niven R. M., Pickering C. A., Fletcher A. M., Oldham L. A., Francis H. M. Prevalence and predictors of work related respiratory symptoms in workers exposed to organic dusts. Occup Environ Med. 1998 Oct;55(10):668–672. doi: 10.1136/oem.55.10.668. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Szozda R. Pneumoconiosis in carbon black workers. J UOEH. 1996 Sep 1;18(3):223–228. doi: 10.7888/juoeh.18.223. [DOI] [PubMed] [Google Scholar]
  16. Szozda R. Stan układu oddechowego pracowników zatrudnionych przy produkcji sadzy technicznej. Med Pr. 1994;45(1):57–61. [PubMed] [Google Scholar]
  17. Szozda R. Układ krazenia pracowników zatrudnionych przy produkcji sadzy technicznej. Med Pr. 1994;45(5):405–410. [PubMed] [Google Scholar]
  18. Tunnicliffe W. S., O'Hickey S. P., Fletcher T. J., Miles J. F., Burge P. S., Ayres J. G. Pulmonary function and respiratory symptoms in a population of airport workers. Occup Environ Med. 1999 Feb;56(2):118–123. doi: 10.1136/oem.56.2.118. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. van Tongeren M. J., Gardiner K. Determinants of inhalable dust exposure in the European carbon black manufacturing industry. Appl Occup Environ Hyg. 2001 Feb;16(2):237–245. doi: 10.1080/104732201460398. [DOI] [PubMed] [Google Scholar]
  20. van Tongeren M. J., Kromhout H., Gardiner K., Calvert I. A., Harrington J. M. Assessment of the sensitivity of the relation between current exposure to carbon black and lung function parameters when using different grouping schemes. Am J Ind Med. 1999 Nov;36(5):548–556. doi: 10.1002/(sici)1097-0274(199911)36:5<548::aid-ajim7>3.0.co;2-v. [DOI] [PubMed] [Google Scholar]
  21. van Tongeren M. J., Kromhout H., Gardiner K. Trends in levels of inhalable dust exposure, exceedance and overexposure in the European carbon black manufacturing industry. Ann Occup Hyg. 2000 Jun;44(4):271–280. [PubMed] [Google Scholar]
  22. van Tongeren M., Gardiner K., Calvert I., Kromhout H., Harrington J. M. Efficiency of different grouping schemes for dust exposure in the European carbon black respiratory morbidity study. Occup Environ Med. 1997 Oct;54(10):714–719. doi: 10.1136/oem.54.10.714. [DOI] [PMC free article] [PubMed] [Google Scholar]

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