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. 2003 Oct;60(10):739–745. doi: 10.1136/oem.60.10.739

Health status as a potential effect modifier of the relation between noise annoyance and incidence of ischaemic heart disease

W Babisch 1, H Ising 1, J Gallacher 1
PMCID: PMC1740389  PMID: 14504361

Abstract

Aims: Traffic noise is a psychosocial stressor. Epidemiological studies suggest chronic noise stress to be a risk factor for cardiovascular disorders.

Methods: In a prospective cohort study, the association between annoyance and disturbances due to road traffic noise and the incidence of ischaemic heart disease (IHD) was studied in 3950 middle aged men.

Results: Depending on the questionnaire item, non-significant odds ratios for IHD incidence ranging from 0.9 to 1.4 were found for the highly noise annoyed/disturbed subjects when compared with the less annoyed/disturbed subjects, over the six year follow up period. However, this relation was strongly modified by the prevalence of pre-existing chronic diseases. In subjects free of any chronic disease at the beginning of the follow up, significant odds ratios between 1.7 and 3.0 were seen. In the subgroup with chronic diseases no such noise effects were seen. This surprising result of no effect in the group of people with a potential risk, due to pre-existing health problems, may be because of the dilution of the true effect due to recall bias.

Conclusions: Annoyance and disturbance due to road traffic noise is associated with a higher incidence of IHD. Prevalence of disease can be an important effect modifier of the relation between noise annoyance and health outcomes.

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Selected References

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  1. Andrén L., Hansson L., Björkman M., Jonsson A. Noise as a contributory factor in the development of elevated arterial pressure. A study of the mechanisms by which noise may raise blood pressure in man. Acta Med Scand. 1980;207(6):493–498. doi: 10.1111/j.0954-6820.1980.tb09760.x. [DOI] [PubMed] [Google Scholar]
  2. Anticaglia J. R., Cohen A. Extra-auditory effects of noise as a health hazard. Am Ind Hyg Assoc J. 1970 May-Jun;31(3):277–281. doi: 10.1080/0002889708506243. [DOI] [PubMed] [Google Scholar]
  3. Babisch W., Fromme H., Beyer A., Ising H. Increased catecholamine levels in urine in subjects exposed to road traffic noise: the role of stress hormones in noise research. Environ Int. 2001 Jun;26(7-8):475–481. doi: 10.1016/s0160-4120(01)00030-7. [DOI] [PubMed] [Google Scholar]
  4. Babisch W., Ising H., Gallacher J. E., Sweetnam P. M., Elwood P. C. Traffic noise and cardiovascular risk: the Caerphilly and Speedwell studies, third phase--10-year follow up. Arch Environ Health. 1999 May-Jun;54(3):210–216. doi: 10.1080/00039899909602261. [DOI] [PubMed] [Google Scholar]
  5. Babisch Wolfgang. Epidemiological Studies of the Cardiovascular effects of Occupational Noise - A Critical Appraisal. Noise Health. 1998;1(1):24–39. [PubMed] [Google Scholar]
  6. Babisch Wolfgang. The Noise/Stress Concept, Risk Assessment and Research Needs. Noise Health. 2002;4(16):1–11. [PubMed] [Google Scholar]
  7. Babisch Wolfgang. Traffic Noise and Cardiovascular Disease: Epidemiological Review and Synthesis. Noise Health. 2000;2(8):9–32. [PubMed] [Google Scholar]
  8. Bainton D., Baker I. A., Sweetnam P. M., Yarnell J. W., Elwood P. C. Prevalence of ischaemic heart disease: the Caerphilly and Speedwell surveys. Br Heart J. 1988 Feb;59(2):201–206. doi: 10.1136/hrt.59.2.201. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Bainton D., Miller N. E., Bolton C. H., Yarnell J. W., Sweetnam P. M., Baker I. A., Lewis B., Elwood P. C. Plasma triglyceride and high density lipoprotein cholesterol as predictors of ischaemic heart disease in British men. The Caerphilly and Speedwell Collaborative Heart Disease Studies. Br Heart J. 1992 Jul;68(1):60–66. doi: 10.1136/hrt.68.7.60. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Cantrell R. W. Physiological effects of noise. Otolaryngol Clin North Am. 1979 Aug;12(3):537–549. [PubMed] [Google Scholar]
  11. Cott C. A., Gignac M. A., Badley E. M. Determinants of self rated health for Canadians with chronic disease and disability. J Epidemiol Community Health. 1999 Nov;53(11):731–736. doi: 10.1136/jech.53.11.731. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Di Nisi J., Muzet A., Ehrhart J., Libert J. P. Comparison of cardiovascular responses to noise during waking and sleeping in humans. Sleep. 1990 Apr;13(2):108–120. doi: 10.1093/sleep/13.2.108. [DOI] [PubMed] [Google Scholar]
  13. Fallon U. B., Elwood P., Ben-Shlomo Y., Ubbink J. B., Greenwood R., Smith G. D. Homocysteine and ischaemic stroke in men: the Caerphilly study. J Epidemiol Community Health. 2001 Feb;55(2):91–96. doi: 10.1136/jech.55.2.91. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Gallacher J. E., Elwood P. C., Hopkinson C., Rabbitt P. M., Stollery B. T., Sweetnam P. M., Brayne C., Huppert F. A. Cognitive function in the Caerphilly study: associations with age social class, education and mood. Eur J Epidemiol. 1999 Feb;15(2):161–169. doi: 10.1023/a:1007576324313. [DOI] [PubMed] [Google Scholar]
  15. Hatfield J., Job R. F.S., Carter N. L., Peploe P., Taylor R., Morrell S. The influence of psychological factors on self-reported physiological effects of noise. Noise Health. 2001;3(10):1–13. [PubMed] [Google Scholar]
  16. Ising H., Dienel D., Günther T., Markert B. Health effects of traffic noise. Int Arch Occup Environ Health. 1980;47(2):179–190. doi: 10.1007/BF00716376. [DOI] [PubMed] [Google Scholar]
  17. Kjellberg A. Subjective, behavioral and psychophysiological effects of noise. Scand J Work Environ Health. 1990;16 (Suppl 1):29–38. doi: 10.5271/sjweh.1825. [DOI] [PubMed] [Google Scholar]
  18. LEHMANN G., TAMM J. Uber Veränderungen der Kreislaufdynamik des ruhenden Menschen unter Einwirkung von Geräuschen. Int Z Angew Physiol. 1956;16(3):217–227. [PubMed] [Google Scholar]
  19. Lundberg Ulf. Coping with Stress: Neuroendocrine Reactions and Implications for Health. Noise Health. 1999;1(4):67–74. [PubMed] [Google Scholar]
  20. Malmström M., Sundquist J., Johansson S. E. Neighborhood environment and self-reported health status: a multilevel analysis. Am J Public Health. 1999 Aug;89(8):1181–1186. doi: 10.2105/ajph.89.8.1181. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Manderbacka K., Lahelma E., Martikainen P. Examining the continuity of self-rated health. Int J Epidemiol. 1998 Apr;27(2):208–213. doi: 10.1093/ije/27.2.208. [DOI] [PubMed] [Google Scholar]
  22. Maschke C., Rupp T., Hecht K. The influence of stressors on biochemical reactions--a review of present scientific findings with noise. Int J Hyg Environ Health. 2000 Mar;203(1):45–53. doi: 10.1078/S1438-4639(04)70007-3. [DOI] [PubMed] [Google Scholar]
  23. Miedema H. M., Oudshoorn C. G. Annoyance from transportation noise: relationships with exposure metrics DNL and DENL and their confidence intervals. Environ Health Perspect. 2001 Apr;109(4):409–416. doi: 10.1289/ehp.01109409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Miedema H. M., Vos H. Exposure-response relationships for transportation noise. J Acoust Soc Am. 1998 Dec;104(6):3432–3445. doi: 10.1121/1.423927. [DOI] [PubMed] [Google Scholar]
  25. Mosskov J. I., Ettema J. H. IV. Extra-auditory effects in long-term exposure to aircraft and traffic noise. Int Arch Occup Environ Health. 1977 Nov 29;40(3):177–184. doi: 10.1007/BF01842080. [DOI] [PubMed] [Google Scholar]
  26. Ortiz G. A., Argüelles A. E., Crespin H. A., Villafañe C. T. Modifications of epinephrine, norepinephrine, blood lipid fractions and the cardiovascular system produced by noise in an industrial medium. Horm Res. 1974 Jan;5(1):57–64. doi: 10.1159/000178619. [DOI] [PubMed] [Google Scholar]
  27. Passchier-Vermeer W., Passchier W. F. Noise exposure and public health. Environ Health Perspect. 2000 Mar;108 (Suppl 1):123–131. doi: 10.1289/ehp.00108s1123. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Stansfeld S., Gallacher J., Babisch W., Shipley M. Road traffic noise and psychiatric disorder: prospective findings from the Caerphilly Study. BMJ. 1996 Aug 3;313(7052):266–267. doi: 10.1136/bmj.313.7052.266. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Sweetnam P. M., Thomas H. F., Yarnell J. W., Beswick A. D., Baker I. A., Elwood P. C. Fibrinogen, viscosity and the 10-year incidence of ischaemic heart disease. Eur Heart J. 1996 Dec;17(12):1814–1820. doi: 10.1093/oxfordjournals.eurheartj.a014797. [DOI] [PubMed] [Google Scholar]
  30. Winkleby M. A., Ragland D. R., Syme S. L. Self-reported stressors and hypertension: evidence of an inverse association. Am J Epidemiol. 1988 Jan;127(1):124–134. doi: 10.1093/oxfordjournals.aje.a114772. [DOI] [PubMed] [Google Scholar]
  31. Yarnell J. W., Baker I. A., Sweetnam P. M., Bainton D., O'Brien J. R., Whitehead P. J., Elwood P. C. Fibrinogen, viscosity, and white blood cell count are major risk factors for ischemic heart disease. The Caerphilly and Speedwell collaborative heart disease studies. Circulation. 1991 Mar;83(3):836–844. doi: 10.1161/01.cir.83.3.836. [DOI] [PubMed] [Google Scholar]
  32. Yarnell J. W., Sweetnam P. M., Baker I. A., Bainton D. Diagnosis of past history of myocardial infarction in epidemiological studies: an alternative based on the Caerphilly and Speedwell surveys. J Epidemiol Community Health. 1988 Jun;42(2):116–120. doi: 10.1136/jech.42.2.116. [DOI] [PMC free article] [PubMed] [Google Scholar]

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