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. 2003 May;60(5):336–342. doi: 10.1136/oem.60.5.336

Effects of bioaerosol polluted outdoor air on airways of residents: a cross sectional study

C Herr 1, A zur Nieden 1, M Jankofsky 1, N Stilianakis 1, R Boedeker 1, T Eikmann 1
PMCID: PMC1740528  PMID: 12709518

Abstract

Background: Bioaerosol pollution of workplace and home environments mainly affects airways and mucous membranes. The effect of environmental outdoor residential bioaerosol pollution, for example, livestock holdings, farming, and waste disposal plants, is unclear.

Aims: To investigate the perceived health of residents living in areas with measurable outdoor bioaerosol pollution (for example, spores of Aspergillus fumigatus and actinomycetes), and effects of accompanying odours.

Methods: In a cross sectional study, double blinded to ongoing microbial measurements, doctors collected 356 questionnaires from residents near a large scale composting site, and from unexposed controls in 1997. Self reported prevalence of health complaints during the past year, doctors' diagnoses, as well as residential odour annoyance were assessed. Microbiological pollution was measured simultaneously in residential outdoor air.

Results: Concentrations of >105 colony forming units of thermophilic actinomycetes, moulds, and total bacteria/m3 air were measured 200 m from the site, dropping to near background concentrations within 300 m. Positive adjusted associations were observed for residency within 150–200 m from the site versus unexposed controls for self reported health complaints: "waking up due to coughing", odds ratio (OR) 6.59 (95% confidence interval (CI) 2.57 to 17.73); "coughing on rising or during the day", OR 3.18 (95% CI 1.24 to 8.36); "bronchitis", OR 3.59 (95% CI 1.40 to 9.4); and "excessive tiredness", OR 4.27 (95% CI 1.56 to 12.15). Reports of irritative airway complaints were associated with residency in the highest bioaerosol exposure, 150–200 m (versus residency >400–500 m) from the site, and period of residency more than five years, but not residential odour annoyance. Lifetime prevalence of self reported diseases did not differ with exposure.

Conclusions: Bioaerosol pollution of residential outdoor air can occur in concentrations found in occupational environments. For the first time residents exposed to bioaerosol pollution were shown to report irritative respiratory complaints similar to mucous membrane irritation independently of perceived odours.

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Selected References

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  1. Brinton W. T., Vastbinder E. E., Greene J. W., Marx J. J., Jr, Hutcheson R. H., Schaffner W. An outbreak of organic dust toxic syndrome in a college fraternity. JAMA. 1987 Sep 4;258(9):1210–1212. [PubMed] [Google Scholar]
  2. Brown J. E., Masood D., Couser J. I., Patterson R. Hypersensitivity pneumonitis from residential composting: residential composter's lung. Ann Allergy Asthma Immunol. 1995 Jan;74(1):45–47. [PubMed] [Google Scholar]
  3. Bünger J., Antlauf-Lammers M., Schulz T. G., Westphal G. A., Müller M. M., Ruhnau P., Hallier E. Health complaints and immunological markers of exposure to bioaerosols among biowaste collectors and compost workers. Occup Environ Med. 2000 Jul;57(7):458–464. doi: 10.1136/oem.57.7.458. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Carvalheiro M. F., Peterson Y., Rubenowitz E., Rylander R. Bronchial reactivity and work-related symptoms in farmers. Am J Ind Med. 1995 Jan;27(1):65–74. doi: 10.1002/ajim.4700270107. [DOI] [PubMed] [Google Scholar]
  5. Dales R. E., Miller D., McMullen E. Indoor air quality and health: validity and determinants of reported home dampness and moulds. Int J Epidemiol. 1997 Feb;26(1):120–125. doi: 10.1093/ije/26.1.120. [DOI] [PubMed] [Google Scholar]
  6. Douwes J., Wouters I., Dubbeld H., van Zwieten L., Steerenberg P., Doekes G., Heederik D. Upper airway inflammation assessed by nasal lavage in compost workers: A relation with bio-aerosol exposure. Am J Ind Med. 2000 May;37(5):459–468. doi: 10.1002/(sici)1097-0274(200005)37:5<459::aid-ajim2>3.0.co;2-j. [DOI] [PubMed] [Google Scholar]
  7. EL-NAKEEB M. A., LECHEVALIER H. A. Selective isolation of aerobic Actinomycetes. Appl Microbiol. 1963 Mar;11:75–77. doi: 10.1128/am.11.2.75-77.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Eduard W., Heederik D. Methods for quantitative assessment of airborne levels of noninfectious microorganisms in highly contaminated work environments. Am Ind Hyg Assoc J. 1998 Feb;59(2):113–127. doi: 10.1080/15428119891010370. [DOI] [PubMed] [Google Scholar]
  9. Klánová K. The concentrations of mixed populations of fungi in indoor air: rooms with and without mould problems; rooms with and without health complaints. Cent Eur J Public Health. 2000 Feb;8(1):59–61. [PubMed] [Google Scholar]
  10. Kramer M. N., Kurup V. P., Fink J. N. Allergic bronchopulmonary aspergillosis from a contaminated dump site. Am Rev Respir Dis. 1989 Oct;140(4):1086–1088. doi: 10.1164/ajrccm/140.4.1086. [DOI] [PubMed] [Google Scholar]
  11. Lacey J., Crook B. Fungal and actinomycete spores as pollutants of the workplace and occupational allergens. Ann Occup Hyg. 1988;32(4):515–533. doi: 10.1093/annhyg/32.4.515. [DOI] [PubMed] [Google Scholar]
  12. Malmberg P., Rask-Andersen A., Rosenhall L. Exposure to microorganisms associated with allergic alveolitis and febrile reactions to mold dust in farmers. Chest. 1993 Apr;103(4):1202–1209. doi: 10.1378/chest.103.4.1202. [DOI] [PubMed] [Google Scholar]
  13. Peat J. K., Dickerson J., Li J. Effects of damp and mould in the home on respiratory health: a review of the literature. Allergy. 1998 Feb;53(2):120–128. doi: 10.1111/j.1398-9995.1998.tb03859.x. [DOI] [PubMed] [Google Scholar]
  14. Poulsen O. M., Breum N. O., Ebbehøj N., Hansen A. M., Ivens U. I., van Lelieveld D., Malmros P., Matthiasen L., Nielsen B. H., Nielsen E. M. Sorting and recycling of domestic waste. Review of occupational health problems and their possible causes. Sci Total Environ. 1995 May 19;168(1):33–56. doi: 10.1016/0048-9697(95)04521-2. [DOI] [PubMed] [Google Scholar]
  15. Richerson H. B. Unifying concepts underlying the effects of organic dust exposures. Am J Ind Med. 1990;17(1):139–142. doi: 10.1002/ajim.4700170146. [DOI] [PubMed] [Google Scholar]
  16. Rylander R., Etzel R. Introduction and summary: workshop on children's health and indoor mold exposure. Environ Health Perspect. 1999 Jun;107 (Suppl 3):465–468. doi: 10.1289/ehp.99107s3465. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Rylander R., Lin R. H. (1-->3)-beta-D-glucan - relationship to indoor air-related symptoms, allergy and asthma. Toxicology. 2000 Nov 2;152(1-3):47–52. doi: 10.1016/s0300-483x(00)00291-2. [DOI] [PubMed] [Google Scholar]
  18. Schiffman S. S. Livestock odors: implications for human health and well-being. J Anim Sci. 1998 May;76(5):1343–1355. doi: 10.2527/1998.7651343x. [DOI] [PubMed] [Google Scholar]
  19. Shusterman D., Lipscomb J., Neutra R., Satin K. Symptom prevalence and odor-worry interaction near hazardous waste sites. Environ Health Perspect. 1991 Aug;94:25–30. doi: 10.1289/ehp.94-1567940. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Vincken W., Roels P. Hypersensitivity pneumonitis due to Aspergillus fumigatus in compost. Thorax. 1984 Jan;39(1):74–75. doi: 10.1136/thx.39.1.74. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Weber S., Kullman G., Petsonk E., Jones W. G., Olenchock S., Sorenson W., Parker J., Marcelo-Baciu R., Frazer D., Castranova V. Organic dust exposures from compost handling: case presentation and respiratory exposure assessment. Am J Ind Med. 1993 Oct;24(4):365–374. doi: 10.1002/ajim.4700240403. [DOI] [PubMed] [Google Scholar]
  22. Wouters I. M., Douwes J., Doekes G., Thorne P. S., Brunekreef B., Heederik D. J. Increased levels of markers of microbial exposure in homes with indoor storage of organic household waste. Appl Environ Microbiol. 2000 Feb;66(2):627–631. doi: 10.1128/aem.66.2.627-631.2000. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Zhaoming W., Lockey R. F. A review of allergic bronchopulmonary aspergillosis. J Investig Allergol Clin Immunol. 1996 May-Jun;6(3):144–151. [PubMed] [Google Scholar]

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