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. 1996 Jun;64(6):2368–2370. doi: 10.1128/iai.64.6.2368-2370.1996

Phosphorylation of myosin light chain at distinct sites and its association with the cytoskeleton during enteropathogenic Escherichia coli infection.

H A Manjarrez-Hernandez 1, T J Baldwin 1, P H Williams 1, R Haigh 1, S Knutton 1, A Aitken 1
PMCID: PMC174084  PMID: 8675355

Abstract

Myosin light chain, the most prominent host cell phosphoprotein during adhesion of enteropathogenic Escherichia coli to cultured HEp-2 cells, was shown to be distributed between cytosolic and cytoskeletal cell fractions; its association with the cytoskeletal fraction increased with time of enteropathogenic E. coli incubation. Phosphopeptide mapping indicated cytosolic and cytoskeletal myosin light chain phosphorylation at different sites by protein kinase C and myosin light chain kinase.

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Selected References

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