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- Adibi Jennifer J., Perera Frederica P., Jedrychowski Wieslaw, Camann David E., Barr Dana, Jacek Ryszard, Whyatt Robin M. Prenatal exposures to phthalates among women in New York City and Krakow, Poland. Environ Health Perspect. 2003 Nov;111(14):1719–1722. doi: 10.1289/ehp.6235. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Agarwal D. K., Maronpot R. R., Lamb J. C., 4th, Kluwe W. M. Adverse effects of butyl benzyl phthalate on the reproductive and hematopoietic systems of male rats. Toxicology. 1985 Jun 14;35(3):189–206. doi: 10.1016/0300-483x(85)90015-0. [DOI] [PubMed] [Google Scholar]
- Albro P. W., Lavenhar S. R. Metabolism of di(2-ethylhexyl)phthalate. Drug Metab Rev. 1989;21(1):13–34. doi: 10.3109/03602538909029953. [DOI] [PubMed] [Google Scholar]
- Albro P. W., Moore B. Identification of the metabolites of simple phthalate diesters in rat urine. J Chromatogr. 1974 Jul 17;94(0):209–218. doi: 10.1016/s0021-9673(01)92368-4. [DOI] [PubMed] [Google Scholar]
- Albro P. W., Thomas R. O. Enzymatic hydrolysis of di-(2-ethylhexyl) phthalate by lipases. Biochim Biophys Acta. 1973 Jun 21;306(3):380–390. doi: 10.1016/0005-2760(73)90176-8. [DOI] [PubMed] [Google Scholar]
- Albro P. W., Thomas R., Fishbein L. Metabolism of diethylhexyl phthalate by rats. Isolation and characterization of the urinary metabolites. J Chromatogr. 1973 Feb 28;76(2):321–330. doi: 10.1016/s0021-9673(01)96915-8. [DOI] [PubMed] [Google Scholar]
- Barlow Norman J., Foster Paul M. D. Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to Di(n-butyl) phthalate. Toxicol Pathol. 2003 Jul-Aug;31(4):397–410. doi: 10.1080/01926230390202335. [DOI] [PubMed] [Google Scholar]
- Barr Dana B., Silva Manori J., Kato Kayoko, Reidy John A., Malek Nicole A., Hurtz Donald, Sadowski Melissa, Needham Larry L., Calafat Antonia M. Assessing human exposure to phthalates using monoesters and their oxidized metabolites as biomarkers. Environ Health Perspect. 2003 Jul;111(9):1148–1151. doi: 10.1289/ehp.6074. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Becker Kerstin, Seiwert Margarete, Angerer Jürgen, Heger Wolfgang, Koch Holger M., Nagorka Regine, Rosskamp Elke, Schlüter Christoph, Seifert Bernd, Ullrich Detlef. DEHP metabolites in urine of children and DEHP in house dust. Int J Hyg Environ Health. 2004 Oct;207(5):409–417. doi: 10.1078/1438-4639-00309. [DOI] [PubMed] [Google Scholar]
- Blount B. C., Milgram K. E., Silva M. J., Malek N. A., Reidy J. A., Needham L. L., Brock J. W. Quantitative detection of eight phthalate metabolites in human urine using HPLC-APCI-MS/MS. Anal Chem. 2000 Sep 1;72(17):4127–4134. doi: 10.1021/ac000422r. [DOI] [PubMed] [Google Scholar]
- Blount B. C., Silva M. J., Caudill S. P., Needham L. L., Pirkle J. L., Sampson E. J., Lucier G. W., Jackson R. J., Brock J. W. Levels of seven urinary phthalate metabolites in a human reference population. Environ Health Perspect. 2000 Oct;108(10):979–982. doi: 10.1289/ehp.00108979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bornehag Carl-Gustaf, Sundell Jan, Weschler Charles J., Sigsgaard Torben, Lundgren Björn, Hasselgren Mikael, Hägerhed-Engman Linda. The association between asthma and allergic symptoms in children and phthalates in house dust: a nested case-control study. Environ Health Perspect. 2004 Oct;112(14):1393–1397. doi: 10.1289/ehp.7187. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brock J. W., Caudill S. P., Silva M. J., Needham L. L., Hilborn E. D. Phthalate monoesters levels in the urine of young children. Bull Environ Contam Toxicol. 2002 Mar;68(3):309–314. doi: 10.1007/s001280255. [DOI] [PubMed] [Google Scholar]
- Calafat Antonia M., Needham Larry L., Silva Manori J., Lambert George. Exposure to di-(2-ethylhexyl) phthalate among premature neonates in a neonatal intensive care unit. Pediatrics. 2004 May;113(5):e429–e434. doi: 10.1542/peds.113.5.e429. [DOI] [PubMed] [Google Scholar]
- Calafat Antonia M., Slakman A. Ryan, Silva Manori J., Herbert Arnetra R., Needham Larry L. Automated solid phase extraction and quantitative analysis of human milk for 13 phthalate metabolites. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jun 5;805(1):49–56. doi: 10.1016/j.jchromb.2004.02.006. [DOI] [PubMed] [Google Scholar]
- Ching N. P., Jham G. N., Subbarayan C., Bowen D. V., Smit A. L., Jr, Grossi C. E., Hicks R. G., Field F. H., Nealon T. F., Jr Gas chromatographic--mass spectrometric detection of circulating plasticizers in surgical patients. J Chromatogr. 1981 Feb 13;222(2):171–177. doi: 10.1016/s0378-4347(00)81050-6. [DOI] [PubMed] [Google Scholar]
- Cobellis L., Latini G., De Felice C., Razzi S., Paris I., Ruggieri F., Mazzeo P., Petraglia F. High plasma concentrations of di-(2-ethylhexyl)-phthalate in women with endometriosis. Hum Reprod. 2003 Jul;18(7):1512–1515. doi: 10.1093/humrep/deg254. [DOI] [PubMed] [Google Scholar]
- Colón I., Caro D., Bourdony C. J., Rosario O. Identification of phthalate esters in the serum of young Puerto Rican girls with premature breast development. Environ Health Perspect. 2000 Sep;108(9):895–900. doi: 10.1289/ehp.108-2556932. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Davis B. J., Maronpot R. R., Heindel J. J. Di-(2-ethylhexyl) phthalate suppresses estradiol and ovulation in cycling rats. Toxicol Appl Pharmacol. 1994 Oct;128(2):216–223. doi: 10.1006/taap.1994.1200. [DOI] [PubMed] [Google Scholar]
- Davis B. J., Weaver R., Gaines L. J., Heindel J. J. Mono-(2-ethylhexyl) phthalate suppresses estradiol production independent of FSH-cAMP stimulation in rat granulosa cells. Toxicol Appl Pharmacol. 1994 Oct;128(2):224–228. doi: 10.1006/taap.1994.1201. [DOI] [PubMed] [Google Scholar]
- Dirven H. A., van den Broek P. H., Jongeneelen F. J. Determination of four metabolites of the plasticizer di(2-ethylhexyl)phthalate in human urine samples. Int Arch Occup Environ Health. 1993;64(8):555–560. doi: 10.1007/BF00517700. [DOI] [PubMed] [Google Scholar]
- Doelman C. J., Borm P. J., Bast A. Plasticisers and bronchial hyperreactivity. Lancet. 1990 Mar 24;335(8691):725–725. doi: 10.1016/0140-6736(90)90839-w. [DOI] [PubMed] [Google Scholar]
- Dostal L. A., Chapin R. E., Stefanski S. A., Harris M. W., Schwetz B. A. Testicular toxicity and reduced Sertoli cell numbers in neonatal rats by di(2-ethylhexyl)phthalate and the recovery of fertility as adults. Toxicol Appl Pharmacol. 1988 Aug;95(1):104–121. doi: 10.1016/s0041-008x(88)80012-7. [DOI] [PubMed] [Google Scholar]
- Doull J., Cattley R., Elcombe C., Lake B. G., Swenberg J., Wilkinson C., Williams G., van Gemert M. A cancer risk assessment of di(2-ethylhexyl)phthalate: application of the new U.S. EPA Risk Assessment Guidelines. Regul Toxicol Pharmacol. 1999 Jun;29(3):327–357. doi: 10.1006/rtph.1999.1296. [DOI] [PubMed] [Google Scholar]
- Duty Susan M., Calafat Antonia M., Silva Manori J., Brock John W., Ryan Louise, Chen Zuying, Overstreet James, Hauser Russ. The relationship between environmental exposure to phthalates and computer-aided sperm analysis motion parameters. J Androl. 2004 Mar-Apr;25(2):293–302. doi: 10.1002/j.1939-4640.2004.tb02790.x. [DOI] [PubMed] [Google Scholar]
- Duty Susan M., Calafat Antonia M., Silva Manori J., Ryan Louise, Hauser Russ. Phthalate exposure and reproductive hormones in adult men. Hum Reprod. 2004 Dec 9;20(3):604–610. doi: 10.1093/humrep/deh656. [DOI] [PubMed] [Google Scholar]
- Duty Susan M., Silva Manori J., Barr Dana B., Brock John W., Ryan Louise, Chen Zuying, Herrick Robert F., Christiani David C., Hauser Russ. Phthalate exposure and human semen parameters. Epidemiology. 2003 May;14(3):269–277. [PubMed] [Google Scholar]
- Duty Susan M., Singh Narendra P., Silva Manori J., Barr Dana B., Brock John W., Ryan Louise, Herrick Robert F., Christiani David C., Hauser Russ. The relationship between environmental exposures to phthalates and DNA damage in human sperm using the neutral comet assay. Environ Health Perspect. 2003 Jul;111(9):1164–1169. doi: 10.1289/ehp.5756. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ema M., Miyawaki E., Kawashima K. Effects of dibutyl phthalate on reproductive function in pregnant and pseudopregnant rats. Reprod Toxicol. 2000 Jan-Feb;14(1):13–19. doi: 10.1016/s0890-6238(99)00066-0. [DOI] [PubMed] [Google Scholar]
- Ema M., Miyawaki E., Kawashima K. Reproductive effects of butyl benzyl phthalate in pregnant and pseudopregnant rats. Reprod Toxicol. 1998 Mar-Apr;12(2):127–132. doi: 10.1016/s0890-6238(97)00127-5. [DOI] [PubMed] [Google Scholar]
- Ema Makoto, Miyawaki Emiko. Effects on development of the reproductive system in male offspring of rats given butyl benzyl phthalate during late pregnancy. Reprod Toxicol. 2002 Jan-Feb;16(1):71–76. doi: 10.1016/s0890-6238(01)00200-3. [DOI] [PubMed] [Google Scholar]
- Ema Makoto, Miyawaki Emiko, Hirose Akihiko, Kamata Eiichi. Decreased anogenital distance and increased incidence of undescended testes in fetuses of rats given monobenzyl phthalate, a major metabolite of butyl benzyl phthalate. Reprod Toxicol. 2003 Jul-Aug;17(4):407–412. doi: 10.1016/s0890-6238(03)00037-6. [DOI] [PubMed] [Google Scholar]
- Faouzi M. A., Dine T., Gressier B., Kambia K., Luyckx M., Pagniez D., Brunet C., Cazin M., Belabed A., Cazin J. C. Exposure of hemodialysis patients to di-2-ethylhexyl phthalate. Int J Pharm. 1999 Mar 25;180(1):113–121. doi: 10.1016/s0378-5173(98)00411-6. [DOI] [PubMed] [Google Scholar]
- Foster P. M., Lake B. G., Cook M. W., Thomas L. V., Gangolli S. D. Structure-activity requirements for the induction of testicular atrophy by butyl phthalates in immature rats: effect on testicular zinc content. Adv Exp Med Biol. 1981;136(Pt A):445–452. doi: 10.1007/978-1-4757-0674-1_33. [DOI] [PubMed] [Google Scholar]
- Foster P. M., Lake B. G., Thomas L. V., Cook M. W., Gangolli S. D. Studies on the testicular effects and zinc excretion produced by various isomers of monobutyl-o-phthalate in the rat. Chem Biol Interact. 1981 Mar 1;34(2):233–238. doi: 10.1016/0009-2797(81)90134-4. [DOI] [PubMed] [Google Scholar]
- Foster P. M., Mylchreest E., Gaido K. W., Sar M. Effects of phthalate esters on the developing reproductive tract of male rats. Hum Reprod Update. 2001 May-Jun;7(3):231–235. doi: 10.1093/humupd/7.3.231. [DOI] [PubMed] [Google Scholar]
- Foster P. M., Thomas L. V., Cook M. W., Gangolli S. D. Study of the testicular effects and changes in zinc excretion produced by some n-alkyl phthalates in the rat. Toxicol Appl Pharmacol. 1980 Jul;54(3):392–398. doi: 10.1016/0041-008x(80)90165-9. [DOI] [PubMed] [Google Scholar]
- Gray L. E., Jr, Ostby J., Furr J., Price M., Veeramachaneni D. N., Parks L. Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat. Toxicol Sci. 2000 Dec;58(2):350–365. doi: 10.1093/toxsci/58.2.350. [DOI] [PubMed] [Google Scholar]
- Gray T. J., Beamand J. A. Effect of some phthalate esters and other testicular toxins on primary cultures of testicular cells. Food Chem Toxicol. 1984 Feb;22(2):123–131. doi: 10.1016/0278-6915(84)90092-9. [DOI] [PubMed] [Google Scholar]
- Hansen J. Risk for testicular cancer after occupational exposure to plastics. Int J Cancer. 1999 Sep 9;82(6):911–912. doi: 10.1002/(sici)1097-0215(19990909)82:6<911::aid-ijc23>3.0.co;2-o. [DOI] [PubMed] [Google Scholar]
- Hardell L., Ohlson C. G., Fredrikson M. Occupational exposure to polyvinyl chloride as a risk factor for testicular cancer evaluated in a case-control study. Int J Cancer. 1997 Dec 10;73(6):828–830. doi: 10.1002/(sici)1097-0215(19971210)73:6<828::aid-ijc10>3.0.co;2-0. [DOI] [PubMed] [Google Scholar]
- Hauser Russ, Duty Susan, Godfrey-Bailey Linda, Calafat Antonia M. Medications as a source of human exposure to phthalates. Environ Health Perspect. 2004 May;112(6):751–753. doi: 10.1289/ehp.6804. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hauser Russ, Meeker John D., Park Sohee, Silva Manori J., Calafat Antonia M. Temporal variability of urinary phthalate metabolite levels in men of reproductive age. Environ Health Perspect. 2004 Dec;112(17):1734–1740. doi: 10.1289/ehp.7212. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Heindel J. J., Gulati D. K., Mounce R. C., Russell S. R., Lamb J. C., 4th Reproductive toxicity of three phthalic acid esters in a continuous breeding protocol. Fundam Appl Toxicol. 1989 Apr;12(3):508–518. doi: 10.1016/0272-0590(89)90024-9. [DOI] [PubMed] [Google Scholar]
- Higuchi Ty T., Palmer Jennifer S., Gray L. Earl, Jr, Veeramachaneni D. N. Rao. Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or postpubertal exposure. Toxicol Sci. 2003 Mar 7;72(2):301–313. doi: 10.1093/toxsci/kfg036. [DOI] [PubMed] [Google Scholar]
- Holm Anders, Solbu Kasper, Molander Paal, Lundanes Elsa, Greibrokk Tyge. Sensitive biomonitoring of phthalate metabolites in human urine using packed capillary column switching liquid chromatography coupled to electrospray ionization ion-trap mass spectrometry. Anal Bioanal Chem. 2004 Jan 31;378(7):1762–1768. doi: 10.1007/s00216-003-2488-7. [DOI] [PubMed] [Google Scholar]
- Hoppin Jane A., Brock John W., Davis Barbara J., Baird Donna D. Reproducibility of urinary phthalate metabolites in first morning urine samples. Environ Health Perspect. 2002 May;110(5):515–518. doi: 10.1289/ehp.02110515. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hoppin Jane A., Ulmer Ross, London Stephanie J. Phthalate exposure and pulmonary function. Environ Health Perspect. 2004 Apr;112(5):571–574. doi: 10.1289/ehp.6564. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jaakkola J. J., Oie L., Nafstad P., Botten G., Samuelsen S. O., Magnus P. Interior surface materials in the home and the development of bronchial obstruction in young children in Oslo, Norway. Am J Public Health. 1999 Feb;89(2):188–192. doi: 10.2105/ajph.89.2.188. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jaakkola J. J., Verkasalo P. K., Jaakkola N. Plastic wall materials in the home and respiratory health in young children. Am J Public Health. 2000 May;90(5):797–799. doi: 10.2105/ajph.90.5.797. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kato Kayoko, Shoda Sachiko, Takahashi Masakazu, Doi Natsuko, Yoshimura Yoshihiro, Nakazawa Hiroyuki. Determination of three phthalate metabolites in human urine using on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 May 25;788(2):407–411. doi: 10.1016/s1570-0232(03)00041-2. [DOI] [PubMed] [Google Scholar]
- Kato Kayoko, Silva Manori J., Brock John W., Reidy John A., Malek Nicole A., Hodge Carolyn C., Nakazawa Hiroyuki, Needham Larry L., Barr Dana B. Quantitative detection of nine phthalate metabolites in human serum using reversed-phase high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. J Anal Toxicol. 2003 Jul-Aug;27(5):284–289. doi: 10.1093/jat/27.5.284. [DOI] [PubMed] [Google Scholar]
- Kato Kayoko, Silva Manori J., Needham Larry L., Calafat Antonia M. Determination of 16 phthalate metabolites in urine using automated sample preparation and on-line preconcentration/high-performance liquid chromatography/tandem mass spectrometry. Anal Chem. 2005 May 1;77(9):2985–2991. doi: 10.1021/ac0481248. [DOI] [PubMed] [Google Scholar]
- Kato Kayoko, Silva Manori J., Reidy John A., Hurtz Donald, 3rd, Malek Nicole A., Needham Larry L., Nakazawa Hiroyuki, Barr Dana B., Calafat Antonia M. Mono(2-ethyl-5-hydroxyhexyl) phthalate and mono-(2-ethyl-5-oxohexyl) phthalate as biomarkers for human exposure assessment to di-(2-ethylhexyl) phthalate. Environ Health Perspect. 2004 Mar;112(3):327–330. doi: 10.1289/ehp.6663. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Klaunig James E., Babich Michael A., Baetcke Karl P., Cook Jon C., Corton J. Chris, David Raymond M., DeLuca John G., Lai David Y., McKee Richard H., Peters Jeffrey M. PPARalpha agonist-induced rodent tumors: modes of action and human relevance. Crit Rev Toxicol. 2003;33(6):655–780. doi: 10.1080/713608372. [DOI] [PubMed] [Google Scholar]
- Koch Holger M., Bolt Hermann M., Angerer Jürgen. Di(2-ethylhexyl)phthalate (DEHP) metabolites in human urine and serum after a single oral dose of deuterium-labelled DEHP. Arch Toxicol. 2003 Oct 24;78(3):123–130. doi: 10.1007/s00204-003-0522-3. [DOI] [PubMed] [Google Scholar]
- Koch Holger M., Drexler Hans, Angerer Jürgen. Internal exposure of nursery-school children and their parents and teachers to di(2-ethylhexyl)phthalate (DEHP). Int J Hyg Environ Health. 2004 Jan;207(1):15–22. doi: 10.1078/1438-4639-00270. [DOI] [PubMed] [Google Scholar]
- Koch Holger M., Gonzalez-Reche Luis M., Angerer Jürgen. On-line clean-up by multidimensional liquid chromatography-electrospray ionization tandem mass spectrometry for high throughput quantification of primary and secondary phthalate metabolites in human urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jan 25;784(1):169–182. doi: 10.1016/s1570-0232(02)00785-7. [DOI] [PubMed] [Google Scholar]
- Koch Holger M., Preuss Ralf, Drexler Hans, Angerer Jürgen. Exposure of nursery school children and their parents and teachers to di-n-butylphthalate and butylbenzylphthalate. Int Arch Occup Environ Health. 2005 Mar 18;78(3):223–229. doi: 10.1007/s00420-004-0570-x. [DOI] [PubMed] [Google Scholar]
- Koch Holger M., Rossbach Bernd, Drexler Hans, Angerer Jürgen. Internal exposure of the general population to DEHP and other phthalates--determination of secondary and primary phthalate monoester metabolites in urine. Environ Res. 2003 Oct;93(2):177–185. doi: 10.1016/s0013-9351(03)00083-5. [DOI] [PubMed] [Google Scholar]
- Kurata Y., Kidachi F., Yokoyama M., Toyota N., Tsuchitani M., Katoh M. Subchronic toxicity of Di(2-ethylhexyl)phthalate in common marmosets: lack of hepatic peroxisome proliferation, testicular atrophy, or pancreatic acinar cell hyperplasia. Toxicol Sci. 1998 Mar;42(1):49–56. doi: 10.1006/toxs.1997.2414. [DOI] [PubMed] [Google Scholar]
- Latini Giuseppe, De Felice Claudio, Presta Giuseppe, Del Vecchio Antonio, Paris Irma, Ruggieri Fabrizio, Mazzeo Pietro. In utero exposure to di-(2-ethylhexyl)phthalate and duration of human pregnancy. Environ Health Perspect. 2003 Nov;111(14):1783–1785. doi: 10.1289/ehp.6202. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Li Hui, Kim Kwan Hee. Effects of mono-(2-ethylhexyl) phthalate on fetal and neonatal rat testis organ cultures. Biol Reprod. 2003 Aug 6;69(6):1964–1972. doi: 10.1095/biolreprod.103.018895. [DOI] [PubMed] [Google Scholar]
- Li L. H., Jester W. F., Jr, Laslett A. L., Orth J. M. A single dose of Di-(2-ethylhexyl) phthalate in neonatal rats alters gonocytes, reduces sertoli cell proliferation, and decreases cyclin D2 expression. Toxicol Appl Pharmacol. 2000 Aug 1;166(3):222–229. doi: 10.1006/taap.2000.8972. [DOI] [PubMed] [Google Scholar]
- Li L. H., Jester W. F., Jr, Orth J. M. Effects of relatively low levels of mono-(2-ethylhexyl) phthalate on cocultured Sertoli cells and gonocytes from neonatal rats. Toxicol Appl Pharmacol. 1998 Dec;153(2):258–265. doi: 10.1006/taap.1998.8550. [DOI] [PubMed] [Google Scholar]
- Lovekamp T. N., Davis B. J. Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells. Toxicol Appl Pharmacol. 2001 May 1;172(3):217–224. doi: 10.1006/taap.2001.9156. [DOI] [PubMed] [Google Scholar]
- McKee R. H., El-Hawari M., Stoltz M., Pallas F., Lington A. W. Absorption, disposition and metabolism of di-isononyl phthalate (DINP) in F-344 rats. J Appl Toxicol. 2002 Sep-Oct;22(5):293–302. doi: 10.1002/jat.861. [DOI] [PubMed] [Google Scholar]
- McKee Richard H., Toxicology Research Task Group, Phthalate Esters Panel American Chemistry Council Phthalate exposure and early thelarche. Environ Health Perspect. 2004 Jul;112(10):A541–A543. doi: 10.1289/ehp.112-a541b. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Melnick R. L. Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)phthalate (DEHP)? Environ Health Perspect. 2001 May;109(5):437–442. doi: 10.1289/ehp.01109437. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mettang T., Thomas S., Kiefer T., Fischer F. P., Kuhlmann U., Wodarz R., Rettenmeier A. W. Uraemic pruritus and exposure to di(2-ethylhexyl) phthalate (DEHP) in haemodialysis patients. Nephrol Dial Transplant. 1996 Dec;11(12):2439–2443. doi: 10.1093/oxfordjournals.ndt.a027211. [DOI] [PubMed] [Google Scholar]
- Milkov L. E., Aldyreva M. V., Popova T. B., Lopukhova K. A., Makarenko Y. L., Malyar L. M., Shakhova T. K. Health status of workers exposed to phthalate plasticizers in the manufacture of artificial leather and films based on PVC resins. Environ Health Perspect. 1973 Jan;3:175–178. doi: 10.1289/ehp.7303175. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Modigh Cecilia M., Bodin S. Lennart V., Lillienberg Linnéa, Dahlman-Höglund Anna, Akesson Bengt, Axelsson Gösta. Time to pregnancy among partners of men exposed to di(2-ethylhexyl)phthalate. Scand J Work Environ Health. 2002 Dec;28(6):418–428. doi: 10.5271/sjweh.694. [DOI] [PubMed] [Google Scholar]
- Murature D. A., Tang S. Y., Steinhardt G., Dougherty R. C. Phthalate esters and semen quality parameters. Biomed Environ Mass Spectrom. 1987 Aug;14(8):473–477. doi: 10.1002/bms.1200140815. [DOI] [PubMed] [Google Scholar]
- Mylchreest E., Cattley R. C., Foster P. M. Male reproductive tract malformations in rats following gestational and lactational exposure to Di(n-butyl) phthalate: an antiandrogenic mechanism? Toxicol Sci. 1998 May;43(1):47–60. doi: 10.1006/toxs.1998.2436. [DOI] [PubMed] [Google Scholar]
- Mylchreest E., Sar M., Cattley R. C., Foster P. M. Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide. Toxicol Appl Pharmacol. 1999 Apr 15;156(2):81–95. doi: 10.1006/taap.1999.8643. [DOI] [PubMed] [Google Scholar]
- Mylchreest E., Wallace D. G., Cattley R. C., Foster P. M. Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to Di(n-butyl) phthalate during late gestation. Toxicol Sci. 2000 May;55(1):143–151. doi: 10.1093/toxsci/55.1.143. [DOI] [PubMed] [Google Scholar]
- Nielsen J., Akesson B., Skerfving S. Phthalate ester exposure--air levels and health of workers processing polyvinylchloride. Am Ind Hyg Assoc J. 1985 Nov;46(11):643–647. doi: 10.1080/15298668591395463. [DOI] [PubMed] [Google Scholar]
- Oie L., Hersoug L. G., Madsen J. O. Residential exposure to plasticizers and its possible role in the pathogenesis of asthma. Environ Health Perspect. 1997 Sep;105(9):972–978. doi: 10.1289/ehp.97105972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Oie L., Nafstad P., Botten G., Magnus P., Jaakkola J. K. Ventilation in homes and bronchial obstruction in young children. Epidemiology. 1999 May;10(3):294–299. doi: 10.1097/00001648-199905000-00018. [DOI] [PubMed] [Google Scholar]
- Parks L. G., Ostby J. S., Lambright C. R., Abbott B. D., Klinefelter G. R., Barlow N. J., Gray L. E., Jr The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat. Toxicol Sci. 2000 Dec;58(2):339–349. doi: 10.1093/toxsci/58.2.339. [DOI] [PubMed] [Google Scholar]
- Parmar D., Srivastava S. P., Seth P. K. Effect of di(2-ethylhexyl)phthalate (DEHP) on spermatogenesis in adult rats. Toxicology. 1986 Dec 1;42(1):47–55. doi: 10.1016/0300-483x(86)90091-0. [DOI] [PubMed] [Google Scholar]
- Pierik Frank H., Burdorf Alex, Deddens James A., Juttmann Rikard E., Weber Rob F. A. Maternal and paternal risk factors for cryptorchidism and hypospadias: a case-control study in newborn boys. Environ Health Perspect. 2004 Nov;112(15):1570–1576. doi: 10.1289/ehp.7243. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pollack G. M., Buchanan J. F., Slaughter R. L., Kohli R. K., Shen D. D. Circulating concentrations of di(2-ethylhexyl) phthalate and its de-esterified phthalic acid products following plasticizer exposure in patients receiving hemodialysis. Toxicol Appl Pharmacol. 1985 Jun 30;79(2):257–267. doi: 10.1016/0041-008x(85)90347-3. [DOI] [PubMed] [Google Scholar]
- Ponsonby Anne-Louise, Dwyer Terence, Kemp Andrew, Cochrane Jennifer, Couper David, Carmichael Allan. Synthetic bedding and wheeze in childhood. Epidemiology. 2003 Jan;14(1):37–44. doi: 10.1097/00001648-200301000-00012. [DOI] [PubMed] [Google Scholar]
- Preuss Ralf, Koch Holger M., Angerer Jürgen. Biological monitoring of the five major metabolites of di-(2-ethylhexyl)phthalate (DEHP) in human urine using column-switching liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Feb 25;816(1-2):269–280. doi: 10.1016/j.jchromb.2004.11.048. [DOI] [PubMed] [Google Scholar]
- Rais-Bahrami Khodayar, Nunez Susan, Revenis Mary E., Luban Naomi L. C., Short Billie L. Follow-up study of adolescents exposed to di(2-ethylhexyl) phthalate (DEHP) as neonates on extracorporeal membrane oxygenation (ECMO) support. Environ Health Perspect. 2004 Sep;112(13):1339–1340. doi: 10.1289/ehp.6901. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rozati Roya, Reddy P. P., Reddanna P., Mujtaba Rubina. Role of environmental estrogens in the deterioration of male factor fertility. Fertil Steril. 2002 Dec;78(6):1187–1194. doi: 10.1016/s0015-0282(02)04389-3. [DOI] [PubMed] [Google Scholar]
- Rudel Ruthann A., Camann David E., Spengler John D., Korn Leo R., Brody Julia G. Phthalates, alkylphenols, pesticides, polybrominated diphenyl ethers, and other endocrine-disrupting compounds in indoor air and dust. Environ Sci Technol. 2003 Oct 15;37(20):4543–4553. doi: 10.1021/es0264596. [DOI] [PubMed] [Google Scholar]
- Shea Katherine M., American Academy of Pediatrics Committee on Environmental Health Pediatric exposure and potential toxicity of phthalate plasticizers. Pediatrics. 2003 Jun;111(6 Pt 1):1467–1474. doi: 10.1542/peds.111.6.1467. [DOI] [PubMed] [Google Scholar]
- Shneider B., Schena J., Truog R., Jacobson M., Kevy S. Exposure to di(2-ethylhexyl)phthalate in infants receiving extracorporeal membrane oxygenation. N Engl J Med. 1989 Jun 8;320(23):1563–1563. doi: 10.1056/NEJM198906083202323. [DOI] [PubMed] [Google Scholar]
- Silva Manori J., Barr Dana B., Reidy John A., Kato Kayoko, Malek Nicole A., Hodge Carolyn C., Hurtz Donald, 3rd, Calafat Antonia M., Needham Larry L., Brock John W. Glucuronidation patterns of common urinary and serum monoester phthalate metabolites. Arch Toxicol. 2003 Jun 28;77(10):561–567. doi: 10.1007/s00204-003-0486-3. [DOI] [PubMed] [Google Scholar]
- Silva Manori J., Barr Dana B., Reidy John A., Malek Nicole A., Hodge Carolyn C., Caudill Samuel P., Brock John W., Needham Larry L., Calafat Antonia M. Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000. Environ Health Perspect. 2004 Mar;112(3):331–338. doi: 10.1289/ehp.6723. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Silva Manori J., Kato Kayoko, Gray Earl L., Wolf Cynthia, Needham Larry L., Calafat Antonia M. Urinary metabolites of di-n-octyl phthalate in rats. Toxicology. 2005 Jun 1;210(2-3):123–133. doi: 10.1016/j.tox.2005.01.012. [DOI] [PubMed] [Google Scholar]
- Silva Manori J., Malek Nicole A., Hodge Carolyn C., Reidy John A., Kato Kayoko, Barr Dana B., Needham Larry L., Brock John W. Improved quantitative detection of 11 urinary phthalate metabolites in humans using liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jun 15;789(2):393–404. doi: 10.1016/s1570-0232(03)00164-8. [DOI] [PubMed] [Google Scholar]
- Silva Manori J., Slakman A. Ryan, Reidy John A., Preau James L., Jr, Herbert Arnetra R., Samandar Ella, Needham Larry L., Calafat Antonia M. Analysis of human urine for fifteen phthalate metabolites using automated solid-phase extraction. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jun 5;805(1):161–167. doi: 10.1016/j.jchromb.2004.02.038. [DOI] [PubMed] [Google Scholar]
- Sjöberg P., Lindqvist N. G., Plöen L. Age-dependent response of the rat testes to di(2-ethylhexyl) phthalate. Environ Health Perspect. 1986 Mar;65:237–242. doi: 10.1289/ehp.65-1474698. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Skakkebaek N. E., Rajpert-De Meyts E., Main K. M. Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum Reprod. 2001 May;16(5):972–978. doi: 10.1093/humrep/16.5.972. [DOI] [PubMed] [Google Scholar]
- Srivastava S. P., Srivastava S., Saxena D. K., Chandra S. V., Seth P. K. Testicular effects of di-n-butyl phthalate (DBP): biochemical and histopathological alterations. Arch Toxicol. 1990;64(2):148–152. doi: 10.1007/BF01974401. [DOI] [PubMed] [Google Scholar]
- Takatori S., Kitagawa Y., Kitagawa M., Nakazawa H., Hori S. Determination of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate in human serum using liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 May 25;804(2):397–401. doi: 10.1016/j.jchromb.2004.01.056. [DOI] [PubMed] [Google Scholar]
- Tyl Rochelle W., Myers Christina B., Marr Melissa C., Fail Patricia A., Seely John C., Brine Dolores R., Barter Robert A., Butala John H. Reproductive toxicity evaluation of dietary butyl benzyl phthalate (BBP) in rats. Reprod Toxicol. 2004 Mar-Apr;18(2):241–264. doi: 10.1016/j.reprotox.2003.10.006. [DOI] [PubMed] [Google Scholar]
- Van Tongeren Martie, Nieuwenhuijsen Mark J., Gardiner Kerry, Armstrong Ben, Vrijheid Martine, Dolk Helen, Botting Beverly. A job-exposure matrix for potential endocrine-disrupting chemicals developed for a study into the association between maternal occupational exposure and hypospadias. Ann Occup Hyg. 2002 Jul;46(5):465–477. doi: 10.1093/annhyg/mef053. [DOI] [PubMed] [Google Scholar]
- Vrijheid M., Armstrong B., Dolk H., van Tongeren M., Botting B. Risk of hypospadias in relation to maternal occupational exposure to potential endocrine disrupting chemicals. Occup Environ Med. 2003 Aug;60(8):543–550. doi: 10.1136/oem.60.8.543. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ward J. M., Peters J. M., Perella C. M., Gonzalez F. J. Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor alpha-null mice. Toxicol Pathol. 1998 Mar-Apr;26(2):240–246. doi: 10.1177/019262339802600208. [DOI] [PubMed] [Google Scholar]
- Zacharewski T. R., Meek M. D., Clemons J. H., Wu Z. F., Fielden M. R., Matthews J. B. Examination of the in vitro and in vivo estrogenic activities of eight commercial phthalate esters. Toxicol Sci. 1998 Dec;46(2):282–293. doi: 10.1006/toxs.1998.2505. [DOI] [PubMed] [Google Scholar]
