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. 1996 Jul;64(7):2839–2841. doi: 10.1128/iai.64.7.2839-2841.1996

Species-, serogroup-, and serovar-specific epitopes are juxtaposed in variable sequence region 4 of the major outer membrane proteins of some Chlamydia trachomatis serovars.

B E Batteiger 1, P M Lin 1, R B Jones 1, B J Van Der Pol 1
PMCID: PMC174151  PMID: 8698520

Abstract

Synthetic peptides and murine monoclonal antibodies were used to map cross-reactive chlamydial epitopes. A species-specific epitope in the central region of variable sequence region 4 abuts the amino-terminal end of a B-serogroup-specific or F/G-serogroup-specific epitope, which in turn abuts known serovar-specific epitopes. The carboxyl-terminal portion of variable sequence region 4 (residues 297 to 314) comprises a region of end-to-end B-cell epitopes in some serovars of the B and F/G serogroups.

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Selected References

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