Skip to main content
NCBI home page
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 2000 Aug;76(898):469–472. doi: 10.1136/pmj.76.898.469

Chronic inflammatory bowel disease in children: a complex problem in management

J Walker-Smith
PMCID: PMC1741682  PMID: 10908372

Full Text

The Full Text of this article is available as a PDF (122.2 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Armitage E., Drummond H., Ghosh S., Ferguson A. Incidence of juvenile-onset Crohn's disease in Scotland. Lancet. 1999 May 1;353(9163):1496–1497. doi: 10.1016/S0140-6736(99)00333-5. [DOI] [PubMed] [Google Scholar]
  2. Bartram C. I., Halligan S. Radiological investigation of chronic inflammatory bowel disease in childhood. Baillieres Clin Gastroenterol. 1994 Mar;8(1):101–119. doi: 10.1016/s0950-3528(06)80021-7. [DOI] [PubMed] [Google Scholar]
  3. Beattie R. M., Schiffrin E. J., Donnet-Hughes A., Huggett A. C., Domizio P., MacDonald T. T., Walker-Smith J. A. Polymeric nutrition as the primary therapy in children with small bowel Crohn's disease. Aliment Pharmacol Ther. 1994 Dec;8(6):609–615. doi: 10.1111/j.1365-2036.1994.tb00338.x. [DOI] [PubMed] [Google Scholar]
  4. Beattie R. M., Walker-Smith J. A., Murch S. H. Indications for investigation of chronic gastrointestinal symptoms. Arch Dis Child. 1995 Oct;73(4):354–355. doi: 10.1136/adc.73.4.354. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Booth I. W., Harries J. T. Inflammatory bowel disease in childhood. Gut. 1984 Feb;25(2):188–202. doi: 10.1136/gut.25.2.188. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Brain C. E., Savage M. O. Growth and puberty in chronic inflammatory bowel disease. Baillieres Clin Gastroenterol. 1994 Mar;8(1):83–100. doi: 10.1016/s0950-3528(06)80020-5. [DOI] [PubMed] [Google Scholar]
  7. Breese E. J., Michie C. A., Nicholls S. W., Williams C. B., Domizio P., Walker-Smith J. A., MacDonald T. T. The effect of treatment on lymphokine-secreting cells in the intestinal mucosa of children with Crohn's disease. Aliment Pharmacol Ther. 1995 Oct;9(5):547–552. doi: 10.1111/j.1365-2036.1995.tb00419.x. [DOI] [PubMed] [Google Scholar]
  8. Casson D. H., Davies S. E., Thomson M. A., Lewis A., Walker-Smith J. A., Murch S. H. Low-dose intravenous azathioprine may be effective in the management of acute fulminant colitis complicating inflammatory bowel disease. Aliment Pharmacol Ther. 1999 Jul;13(7):891–895. doi: 10.1046/j.1365-2036.1999.00559.x. [DOI] [PubMed] [Google Scholar]
  9. Chong S. K., Bartram C., Campbell C. A., Williams C. B., Blackshaw A. J., Walker-Smith J. A. Chronic inflammatory bowel disease in childhood. Br Med J (Clin Res Ed) 1982 Jan 9;284(6309):101–103. doi: 10.1136/bmj.284.6309.101. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Chong S. K., Blackshaw A. J., Boyle S., Williams C. B., Walker-Smith J. A. Histological diagnosis of chronic inflammatory bowel disease in childhood. Gut. 1985 Jan;26(1):55–59. doi: 10.1136/gut.26.1.55. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. De Benedetti F., Alonzi T., Moretta A., Lazzaro D., Costa P., Poli V., Martini A., Ciliberto G., Fattori E. Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I. A model for stunted growth in children with chronic inflammation. J Clin Invest. 1997 Feb 15;99(4):643–650. doi: 10.1172/JCI119207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Domizio P. Pathology of chronic inflammatory bowel disease in children. Baillieres Clin Gastroenterol. 1994 Mar;8(1):35–63. doi: 10.1016/s0950-3528(06)80018-7. [DOI] [PubMed] [Google Scholar]
  13. Durno C., Sherman P., Harris K., Smith C., Dupuis A., Shandling B., Wesson D., Filler R., Superina R., Griffiths A. Outcome after ileoanal anastomosis in pediatric patients with ulcerative colitis. J Pediatr Gastroenterol Nutr. 1998 Nov;27(5):501–507. doi: 10.1097/00005176-199811000-00001. [DOI] [PubMed] [Google Scholar]
  14. Evans C. M., Kirk J. M., Savage M. O., Walker-Smith J. A. Growth after gut resection for Crohn's disease. Arch Dis Child. 1991 Mar;66(3):370–370. doi: 10.1136/adc.66.3.370. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Fell J. M., Paintin M., Arnaud-Battandier F., Beattie R. M., Hollis A., Kitching P., Donnet-Hughes A., MacDonald T. T., Walker-Smith J. A. Mucosal healing and a fall in mucosal pro-inflammatory cytokine mRNA induced by a specific oral polymeric diet in paediatric Crohn's disease. Aliment Pharmacol Ther. 2000 Mar;14(3):281–289. doi: 10.1046/j.1365-2036.2000.00707.x. [DOI] [PubMed] [Google Scholar]
  16. Kirschner B. S., Klich J. R., Kalman S. S., deFavaro M. V., Rosenberg I. H. Reversal of growth retardation in Crohn's disease with therapy emphasizing oral nutritional restitution. Gastroenterology. 1981 Jan;80(1):10–15. [PubMed] [Google Scholar]
  17. Kirschner B. S., Sutton M. M. Somatomedin-C levels in growth-impaired children and adolescents with chronic inflammatory bowel disease. Gastroenterology. 1986 Oct;91(4):830–836. doi: 10.1016/0016-5085(86)90683-9. [DOI] [PubMed] [Google Scholar]
  18. Lee J. C., Bridger S., McGregor C., Macpherson A. J., Jones J. E. Why children with inflammatory bowel disease are diagnosed at a younger age than their affected parent. Gut. 1999 Jun;44(6):808–811. doi: 10.1136/gut.44.6.808. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Lehrnbecher T., Kontny H. U., Jeschke R. Metastatic Crohn's disease in a 9-year-old boy. J Pediatr Gastroenterol Nutr. 1999 Mar;28(3):321–323. doi: 10.1097/00005176-199903000-00021. [DOI] [PubMed] [Google Scholar]
  20. Murch S. H., Lamkin V. A., Savage M. O., Walker-Smith J. A., MacDonald T. T. Serum concentrations of tumour necrosis factor alpha in childhood chronic inflammatory bowel disease. Gut. 1991 Aug;32(8):913–917. doi: 10.1136/gut.32.8.913. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Murch S. H., Walker-Smith J. A. Medical management of chronic inflammatory bowel disease. Baillieres Clin Gastroenterol. 1994 Mar;8(1):133–148. doi: 10.1016/s0950-3528(06)80023-0. [DOI] [PubMed] [Google Scholar]
  22. O'Donoghue D. P., Dawson A. M. Crohn's disease in childhood. Arch Dis Child. 1977 Aug;52(8):627–632. doi: 10.1136/adc.52.8.627. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Sanderson I. R., Udeen S., Davies P. S., Savage M. O., Walker-Smith J. A. Remission induced by an elemental diet in small bowel Crohn's disease. Arch Dis Child. 1987 Feb;62(2):123–127. doi: 10.1136/adc.62.2.123. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Sanderson I. R., Walker-Smith J. A. Crohn's disease in childhood. Br J Surg. 1985 Sep;72 (Suppl):S87–S90. doi: 10.1002/bjs.1800721345. [DOI] [PubMed] [Google Scholar]
  25. Shand W. S. Surgical therapy of chronic inflammatory bowel disease in childhood. Baillieres Clin Gastroenterol. 1994 Mar;8(1):149–180. doi: 10.1016/s0950-3528(06)80024-2. [DOI] [PubMed] [Google Scholar]
  26. Thomas A. G., Holly J. M., Taylor F., Miller V. Insulin like growth factor-I, insulin like growth factor binding protein-1, and insulin in childhood Crohn's disease. Gut. 1993 Jul;34(7):944–947. doi: 10.1136/gut.34.7.944. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Thomas A. G., Taylor F., Miller V. Dietary intake and nutritional treatment in childhood Crohn's disease. J Pediatr Gastroenterol Nutr. 1993 Jul;17(1):75–81. doi: 10.1097/00005176-199307000-00011. [DOI] [PubMed] [Google Scholar]
  28. Walker-Smith J. A. Management of growth failure in Crohn's disease. Arch Dis Child. 1996 Oct;75(4):351–354. doi: 10.1136/adc.75.4.351. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Walker-Smith J. A. Therapy of Crohn's disease in childhood. Baillieres Clin Gastroenterol. 1997 Sep;11(3):593–610. doi: 10.1016/s0950-3528(97)90033-6. [DOI] [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES