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. 1996 Aug;64(8):3407–3409. doi: 10.1128/iai.64.8.3407-3409.1996

Interleukin-8 gene expression in Staphylococcus aureus-infected endothelial cells.

L Yao 1, F D Lowy 1, J W Berman 1
PMCID: PMC174238  PMID: 8757884

Abstract

Interleukin-8 (IL-8) plays a crucial role in the migration of neutrophils to bacterium-infected sites. This study investigated IL-8 induction in Staphylococcus aureus-infected endothelial cells (EC). We observed that S. aureus-infected EC were induced to express both IL-8 mRNA and protein, which can promote transmigration of neutrophils across an EC monolayer.

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Selected References

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