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. 2003 Jun;79(932):341–344. doi: 10.1136/pmj.79.932.341

Hospital admissions for human T-cell lymphotropic virus type-1 (HTLV-1) associated diseases in Dominica

O Adedayo 1, G Grell 1, P Bellot 1
PMCID: PMC1742731  PMID: 12840124

Abstract

Human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that is endemic in certain regions of the world, and may account for significant morbidity and mortality among hospitalised patients.

Sixty six HTLV-1 seropositive patients admitted to hospital with HTLV-1 associated diseases from 1995–99 were studied. HTLV-1 screening was done with ELISA and confirmed on western blot testing. There were 32 females (48.5%) and 34 males (51.5%). The mean age was 56 years and the age range was 9–89 years.

The main associated diseases were tropical spastic paraparesis or HTLV-1 associated myelopathy in 18.2% of cases, acute form of adult T-cell leukaemia/lymphoma 7.6%, lymphomas 15.2%, and ectoparasites/endoparasites in 40.9%. HTLV-1 is associated with diseases in Dominica and association with severe forms of strongyloidiasis and scabies is particularly noted.

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Selected References

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