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. 2003 Oct;79(936):575–580. doi: 10.1136/pmj.79.936.575

Prostate cancer management: (1) an update on localised disease

S Bott 1, A Birtle 1, C Taylor 1, R Kirby 1
PMCID: PMC1742848  PMID: 14612600

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Selected References

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  1. Abbou C. C., Salomon L., Hoznek A., Antiphon P., Cicco A., Saint F., Alame W., Bellot J., Chopin D. K. Laparoscopic radical prostatectomy: preliminary results. Urology. 2000 May;55(5):630–634. doi: 10.1016/s0090-4295(00)00502-1. [DOI] [PubMed] [Google Scholar]
  2. Albertsen P. C., Fryback D. G., Storer B. E., Kolon T. F., Fine J. Long-term survival among men with conservatively treated localized prostate cancer. JAMA. 1995 Aug 23;274(8):626–631. [PubMed] [Google Scholar]
  3. Albertsen P. C., Hanley J. A., Gleason D. F., Barry M. J. Competing risk analysis of men aged 55 to 74 years at diagnosis managed conservatively for clinically localized prostate cancer. JAMA. 1998 Sep 16;280(11):975–980. doi: 10.1001/jama.280.11.975. [DOI] [PubMed] [Google Scholar]
  4. Babaian R. J., Troncoso P., Bhadkamkar V. A., Johnston D. A. Analysis of clinicopathologic factors predicting outcome after radical prostatectomy. Cancer. 2001 Apr 15;91(8):1414–1422. [PubMed] [Google Scholar]
  5. Blasko John C., Mate Tim, Sylvester John E., Grimm Peter D., Cavanagh William. Brachytherapy for carcinoma of the prostate: techniques, patient selection, and clinical outcomes. Semin Radiat Oncol. 2002 Jan;12(1):81–94. doi: 10.1053/srao.2002.28667. [DOI] [PubMed] [Google Scholar]
  6. Blute M. L., Bostwick D. G., Seay T. M., Martin S. K., Slezak J. M., Bergstralh E. J., Zincke H. Pathologic classification of prostate carcinoma: the impact of margin status. Cancer. 1998 Mar 1;82(5):902–908. doi: 10.1002/(sici)1097-0142(19980301)82:5<902::aid-cncr15>3.0.co;2-4. [DOI] [PubMed] [Google Scholar]
  7. Bollens R., Vanden Bossche M., Roumeguere T., Damoun A., Ekane S., Hoffmann P., Zlotta A. R., Schulman C. C. Extraperitoneal laparoscopic radical prostatectomy. Results after 50 cases. Eur Urol. 2001 Jul;40(1):65–69. doi: 10.1159/000049750. [DOI] [PubMed] [Google Scholar]
  8. Brawley O. W. Prostate carcinoma incidence and patient mortality: the effects of screening and early detection. Cancer. 1997 Nov 1;80(9):1857–1863. doi: 10.1002/(sici)1097-0142(19971101)80:9<1857::aid-cncr26>3.0.co;2-3. [DOI] [PubMed] [Google Scholar]
  9. Cadeddu J. A., Partin A. W., DeWeese T. L., Walsh P. C. Long-term results of radiation therapy for prostate cancer recurrence following radical prostatectomy. J Urol. 1998 Jan;159(1):173–178. doi: 10.1016/s0022-5347(01)64047-3. [DOI] [PubMed] [Google Scholar]
  10. Catalona W. J., Carvalhal G. F., Mager D. E., Smith D. S. Potency, continence and complication rates in 1,870 consecutive radical retropubic prostatectomies. J Urol. 1999 Aug;162(2):433–438. [PubMed] [Google Scholar]
  11. Catalona W. J., Ramos C. G., Carvalhal G. F. Contemporary results of anatomic radical prostatectomy. CA Cancer J Clin. 1999 Sep-Oct;49(5):282–296. doi: 10.3322/canjclin.49.5.282. [DOI] [PubMed] [Google Scholar]
  12. Chodak G. W., Thisted R. A., Gerber G. S., Johansson J. E., Adolfsson J., Jones G. W., Chisholm G. D., Moskovitz B., Livne P. M., Warner J. Results of conservative management of clinically localized prostate cancer. N Engl J Med. 1994 Jan 27;330(4):242–248. doi: 10.1056/NEJM199401273300403. [DOI] [PubMed] [Google Scholar]
  13. Coetzee L. J., Hars V., Paulson D. F. Postoperative prostate-specific antigen as a prognostic indicator in patients with margin-positive prostate cancer, undergoing adjuvant radiotherapy after radical prostatectomy. Urology. 1996 Feb;47(2):232–235. doi: 10.1016/s0090-4295(99)80422-1. [DOI] [PubMed] [Google Scholar]
  14. Cox J. D., Gallagher M. J., Hammond E. H., Kaplan R. S., Schellhammer P. F. Consensus statements on radiation therapy of prostate cancer: guidelines for prostate re-biopsy after radiation and for radiation therapy with rising prostate-specific antigen levels after radical prostatectomy. American Society for Therapeutic Radiology and Oncology Consensus Panel. J Clin Oncol. 1999 Apr;17(4):1155–1155. doi: 10.1200/JCO.1999.17.4.1155. [DOI] [PubMed] [Google Scholar]
  15. Dearnaley D. P., Khoo V. S., Norman A. R., Meyer L., Nahum A., Tait D., Yarnold J., Horwich A. Comparison of radiation side-effects of conformal and conventional radiotherapy in prostate cancer: a randomised trial. Lancet. 1999 Jan 23;353(9149):267–272. doi: 10.1016/S0140-6736(98)05180-0. [DOI] [PubMed] [Google Scholar]
  16. Eden C. G., Cahill D., Vass J. A., Adams T. H., Dauleh M. I. Laparoscopic radical prostatectomy: the initial UK series. BJU Int. 2002 Dec;90(9):876–882. doi: 10.1046/j.1464-410x.2002.03049.x. [DOI] [PubMed] [Google Scholar]
  17. Epstein J. I., Pizov G., Walsh P. C. Correlation of pathologic findings with progression after radical retropubic prostatectomy. Cancer. 1993 Jun 1;71(11):3582–3593. doi: 10.1002/1097-0142(19930601)71:11<3582::aid-cncr2820711120>3.0.co;2-y. [DOI] [PubMed] [Google Scholar]
  18. Frazier H. A., Robertson J. E., Paulson D. F. Radical prostatectomy: the pros and cons of the perineal versus retropubic approach. J Urol. 1992 Mar;147(3 Pt 2):888–890. doi: 10.1016/s0022-5347(17)37413-x. [DOI] [PubMed] [Google Scholar]
  19. Graefen Markus, Karakiewicz Pierre I., Cagiannos Ilias, Quinn David I., Henshall Susan M., Grygiel John J., Sutherland Robert L., Stricker Phillip D., Klein Eric, Kupelian Patrick. International validation of a preoperative nomogram for prostate cancer recurrence after radical prostatectomy. J Clin Oncol. 2002 Aug 1;20(15):3206–3212. doi: 10.1200/JCO.2002.12.019. [DOI] [PubMed] [Google Scholar]
  20. Guillonneau B., Vallancien G. Laparoscopic radical prostatectomy: the Montsouris technique. J Urol. 2000 Jun;163(6):1643–1649. doi: 10.1016/s0022-5347(05)67512-x. [DOI] [PubMed] [Google Scholar]
  21. Han M., Partin A. W., Piantadosi S., Epstein J. I., Walsh P. C. Era specific biochemical recurrence-free survival following radical prostatectomy for clinically localized prostate cancer. J Urol. 2001 Aug;166(2):416–419. [PubMed] [Google Scholar]
  22. Hanks Gerald E., Hanlon Alexandra L., Epstein Barry, Horwitz Eric M. Dose response in prostate cancer with 8-12 years' follow-up. Int J Radiat Oncol Biol Phys. 2002 Oct 1;54(2):427–435. doi: 10.1016/s0360-3016(02)02954-1. [DOI] [PubMed] [Google Scholar]
  23. Heidenreich A., Moul J. W., McLeod D. G., Mostofi F. K., Engelmann U. H. The role of retroperitoneal lymphadenectomy in mature teratoma of the testis. J Urol. 1997 Jan;157(1):160–163. [PubMed] [Google Scholar]
  24. Holmberg Lars, Bill-Axelson Anna, Helgesen Fred, Salo Jaakko O., Folmerz Per, Häggman Michael, Andersson Swen-Olof, Spångberg Anders, Busch Christer, Nordling Steg. A randomized trial comparing radical prostatectomy with watchful waiting in early prostate cancer. N Engl J Med. 2002 Sep 12;347(11):781–789. doi: 10.1056/NEJMoa012794. [DOI] [PubMed] [Google Scholar]
  25. Horwich A., Wynne C., Nahum A., Swindell W., Dearnaley D. P. Conformal radiotherapy at the Royal Marsden Hospital (UK). Int J Radiat Biol. 1994 Jan;65(1):117–122. doi: 10.1080/09553009414550161. [DOI] [PubMed] [Google Scholar]
  26. Hugosson J., Aus G., Becker C., Carlsson S., Eriksson H., Lilja H., Lodding P., Tibblin G. Would prostate cancer detected by screening with prostate-specific antigen develop into clinical cancer if left undiagnosed? A comparison of two population-based studies in Sweden. BJU Int. 2000 Jun;85(9):1078–1084. doi: 10.1046/j.1464-410x.2000.00679.x. [DOI] [PubMed] [Google Scholar]
  27. Koppie T. M., Grossfeld G. D., Miller D., Yu J., Stier D., Broering J. M., Lubeck D., Henning J. M., Flanders S. C., Carroll P. R. Patterns of treatment of patients with prostate cancer initially managed with surveillance: results from The CaPSURE database. Cancer of the Prostate Strategic Urological Research Endeavor. J Urol. 2000 Jul;164(1):81–88. [PubMed] [Google Scholar]
  28. Lawton C. A., Winter K., Murray K., Machtay M., Mesic J. B., Hanks G. E., Coughlin C. T., Pilepich M. V. Updated results of the phase III Radiation Therapy Oncology Group (RTOG) trial 85-31 evaluating the potential benefit of androgen suppression following standard radiation therapy for unfavorable prognosis carcinoma of the prostate. Int J Radiat Oncol Biol Phys. 2001 Mar 15;49(4):937–946. doi: 10.1016/s0360-3016(00)01516-9. [DOI] [PubMed] [Google Scholar]
  29. Lee H. H., Warde P., Jewett M. A. Neoadjuvant hormonal therapy in carcinoma of the prostate. BJU Int. 1999 Mar;83(4):438–448. doi: 10.1046/j.1464-410x.1999.00953.x. [DOI] [PubMed] [Google Scholar]
  30. Lu-Yao G. L., Yao S. L. Population-based study of long-term survival in patients with clinically localised prostate cancer. Lancet. 1997 Mar 29;349(9056):906–910. doi: 10.1016/S0140-6736(96)09380-4. [DOI] [PubMed] [Google Scholar]
  31. Martinez Alvaro A., Gustafson Gary, Gonzalez José, Armour Elwood, Mitchell Chris, Edmundson Gregory, Spencer William, Stromberg Jannifer, Huang Raywin, Vicini Frank. Dose escalation using conformal high-dose-rate brachytherapy improves outcome in unfavorable prostate cancer. Int J Radiat Oncol Biol Phys. 2002 Jun 1;53(2):316–327. doi: 10.1016/s0360-3016(02)02733-5. [DOI] [PubMed] [Google Scholar]
  32. Messing E. M., Manola J., Sarosdy M., Wilding G., Crawford E. D., Trump D. Immediate hormonal therapy compared with observation after radical prostatectomy and pelvic lymphadenectomy in men with node-positive prostate cancer. N Engl J Med. 1999 Dec 9;341(24):1781–1788. doi: 10.1056/NEJM199912093412401. [DOI] [PubMed] [Google Scholar]
  33. Montironi R., Diamanti L., Santinelli A., Galetti-Prayer T., Zattoni F., Selvaggi F. P., Pagano F., Bono A. V. Effect of total androgen ablation on pathologic stage and resection limit status of prostate cancer. Initial results of the Italian PROSIT study. Pathol Res Pract. 1999;195(4):201–208. doi: 10.1016/S0344-0338(99)80036-3. [DOI] [PubMed] [Google Scholar]
  34. Nudell D. M., Grossfeld G. D., Weinberg V. K., Roach M., 3rd, Carroll P. R. Radiotherapy after radical prostatectomy: treatment outcomes and failure patterns. Urology. 1999 Dec;54(6):1049–1057. doi: 10.1016/s0090-4295(99)00299-x. [DOI] [PubMed] [Google Scholar]
  35. Nutting Christopher M., Dearnaley David P. Prostate cancer--the Royal Marsden conformal experience. Front Radiat Ther Oncol. 2002;37:196–199. doi: 10.1159/000061318. [DOI] [PubMed] [Google Scholar]
  36. Partin A. W., Kattan M. W., Subong E. N., Walsh P. C., Wojno K. J., Oesterling J. E., Scardino P. T., Pearson J. D. Combination of prostate-specific antigen, clinical stage, and Gleason score to predict pathological stage of localized prostate cancer. A multi-institutional update. JAMA. 1997 May 14;277(18):1445–1451. [PubMed] [Google Scholar]
  37. Peschel R. E., Robnett T. J., Hesse D., King C. R., Ennis R. D., Schiff P. B., Wilson L. D. PSA based review of adjuvant and salvage radiation therapy vs. observation in postoperative prostate cancer patients. Int J Cancer. 2000 Feb 20;90(1):29–36. [PubMed] [Google Scholar]
  38. Pilepich M. V., Winter K., John M. J., Mesic J. B., Sause W., Rubin P., Lawton C., Machtay M., Grignon D. Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate. Int J Radiat Oncol Biol Phys. 2001 Aug 1;50(5):1243–1252. doi: 10.1016/s0360-3016(01)01579-6. [DOI] [PubMed] [Google Scholar]
  39. Poon M., Ruckle H., Bamshad B. R., Tsai C., Webster R., Lui P. Radical retropubic prostatectomy: bladder neck preservation versus reconstruction. J Urol. 2000 Jan;163(1):194–198. doi: 10.1016/s0022-5347(05)68003-2. [DOI] [PubMed] [Google Scholar]
  40. Pound C. R., Partin A. W., Eisenberger M. A., Chan D. W., Pearson J. D., Walsh P. C. Natural history of progression after PSA elevation following radical prostatectomy. JAMA. 1999 May 5;281(17):1591–1597. doi: 10.1001/jama.281.17.1591. [DOI] [PubMed] [Google Scholar]
  41. Pound C. R., Partin A. W., Epstein J. I., Walsh P. C. Prostate-specific antigen after anatomic radical retropubic prostatectomy. Patterns of recurrence and cancer control. Urol Clin North Am. 1997 May;24(2):395–406. doi: 10.1016/s0094-0143(05)70386-4. [DOI] [PubMed] [Google Scholar]
  42. Sakr W. A., Wheeler T. M., Blute M., Bodo M., Calle-Rodrigue R., Henson D. E., Mostofi F. K., Seiffert J., Wojno K., Zincke H. Staging and reporting of prostate cancer--sampling of the radical prostatectomy specimen. Cancer. 1996 Jul 15;78(2):366–368. doi: 10.1002/(SICI)1097-0142(19960715)78:2<366::AID-CNCR29>3.0.CO;2-T. [DOI] [PubMed] [Google Scholar]
  43. Salomon Laurent, Anastasiadis Aristotelis G., Katz Ran, De La Taille Alexandre, Saint Fabien, Vordos Dimitrios, Cicco Anthony, Hoznek Andras, Chopin Dominique, Abbou Clement-Claude. Urinary continence and erectile function: a prospective evaluation of functional results after radical laparoscopic prostatectomy. Eur Urol. 2002 Oct;42(4):338–343. doi: 10.1016/s0302-2838(02)00360-3. [DOI] [PubMed] [Google Scholar]
  44. Scardino P. T., Weaver R., Hudson M. A. Early detection of prostate cancer. Hum Pathol. 1992 Mar;23(3):211–222. doi: 10.1016/0046-8177(92)90102-9. [DOI] [PubMed] [Google Scholar]
  45. See William A., Wirth Manfred P., McLeod David G., Iversen Peter, Klimberg Ira, Gleason Donald, Chodak Gerald, Montie James, Tyrrell Chris, Wallace D. M. A. Bicalutamide as immediate therapy either alone or as adjuvant to standard care of patients with localized or locally advanced prostate cancer: first analysis of the early prostate cancer program. J Urol. 2002 Aug;168(2):429–435. [PubMed] [Google Scholar]
  46. Shibata A., Whittemore A. S. Re: Prostate cancer incidence and mortality in the United States and the United Kingdom. J Natl Cancer Inst. 2001 Jul 18;93(14):1109–1110. doi: 10.1093/jnci/93.14.1109. [DOI] [PubMed] [Google Scholar]
  47. Soloway M. S., Sharifi R., Wajsman Z., McLeod D., Wood D. P., Jr, Puras-Baez A. Randomized prospective study comparing radical prostatectomy alone versus radical prostatectomy preceded by androgen blockade in clinical stage B2 (T2bNxM0) prostate cancer. The Lupron Depot Neoadjuvant Prostate Cancer Study Group. J Urol. 1995 Aug;154(2 Pt 1):424–428. [PubMed] [Google Scholar]
  48. Stamey T. A., Villers A. A., McNeal J. E., Link P. C., Freiha F. S. Positive surgical margins at radical prostatectomy: importance of the apical dissection. J Urol. 1990 Jun;143(6):1166–1173. doi: 10.1016/s0022-5347(17)40216-3. [DOI] [PubMed] [Google Scholar]
  49. Stamey T. A., Yang N., Hay A. R., McNeal J. E., Freiha F. S., Redwine E. Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate. N Engl J Med. 1987 Oct 8;317(15):909–916. doi: 10.1056/NEJM198710083171501. [DOI] [PubMed] [Google Scholar]
  50. Stein A., Smith R. B., deKernion J. B. Salvage radical prostatectomy after failure of curative radiotherapy for adenocarcinoma of prostate. Urology. 1992 Sep;40(3):197–200. doi: 10.1016/0090-4295(92)90473-a. [DOI] [PubMed] [Google Scholar]
  51. Steineck Gunnar, Helgesen Fred, Adolfsson Jan, Dickman Paul W., Johansson Jan-Erik, Norlén Bo Johan, Holmberg Lars, Scandinavian Prostatic Cancer Group Study Number 4 Quality of life after radical prostatectomy or watchful waiting. N Engl J Med. 2002 Sep 12;347(11):790–796. doi: 10.1056/NEJMoa021483. [DOI] [PubMed] [Google Scholar]
  52. Stone N. N., Stock R. G. Complications following permanent prostate brachytherapy. Eur Urol. 2002 Apr;41(4):427–433. doi: 10.1016/s0302-2838(02)00019-2. [DOI] [PubMed] [Google Scholar]
  53. Valicenti R. K., Gomella L. G., Ismail M., Strup S. E., Mulholland S. G., Dicker A. P., Petersen R. O., Newschaffer C. J. The efficacy of early adjuvant radiation therapy for pT3N0 prostate cancer: a matched-pair analysis. Int J Radiat Oncol Biol Phys. 1999 Aug 1;45(1):53–58. doi: 10.1016/s0360-3016(99)00169-8. [DOI] [PubMed] [Google Scholar]
  54. Van Poppel H., De Ridder D., Elgamal A. A., Van de Voorde W., Werbrouck P., Ackaert K., Oyen R., Pittomvils G., Baert L. Neoadjuvant hormonal therapy before radical prostatectomy decreases the number of positive surgical margins in stage T2 prostate cancer: interim results of a prospective randomized trial. The Belgian Uro-Oncological Study Group. J Urol. 1995 Aug;154(2 Pt 1):429–434. doi: 10.1097/00005392-199508000-00027. [DOI] [PubMed] [Google Scholar]
  55. Walsh P. C., Donker P. J. Impotence following radical prostatectomy: insight into etiology and prevention. J Urol. 1982 Sep;128(3):492–497. doi: 10.1016/s0022-5347(17)53012-8. [DOI] [PubMed] [Google Scholar]
  56. Walsh P. C., Partin A. W., Epstein J. I. Cancer control and quality of life following anatomical radical retropubic prostatectomy: results at 10 years. J Urol. 1994 Nov;152(5 Pt 2):1831–1836. doi: 10.1016/s0022-5347(17)32396-0. [DOI] [PubMed] [Google Scholar]
  57. Walsh P. C. Patient-reported urinary continence and sexual function after anatomic radical prostatectomy. J Urol. 2000 Jul;164(1):242–242. [PubMed] [Google Scholar]
  58. Walsh Patrick C. Surgery and the reduction of mortality from prostate cancer. N Engl J Med. 2002 Sep 12;347(11):839–840. doi: 10.1056/NEJMe020089. [DOI] [PubMed] [Google Scholar]
  59. Welch H. G., Schwartz L. M., Woloshin S. Are increasing 5-year survival rates evidence of success against cancer? JAMA. 2000 Jun 14;283(22):2975–2978. doi: 10.1001/jama.283.22.2975. [DOI] [PubMed] [Google Scholar]
  60. Weldon V. E., Tavel F. R., Neuwirth H. Continence, potency and morbidity after radical perineal prostatectomy. J Urol. 1997 Oct;158(4):1470–1475. [PubMed] [Google Scholar]
  61. Wieder J. A., Soloway M. S. Incidence, etiology, location, prevention and treatment of positive surgical margins after radical prostatectomy for prostate cancer. J Urol. 1998 Aug;160(2):299–315. [PubMed] [Google Scholar]
  62. Zincke H., Oesterling J. E., Blute M. L., Bergstralh E. J., Myers R. P., Barrett D. M. Long-term (15 years) results after radical prostatectomy for clinically localized (stage T2c or lower) prostate cancer. J Urol. 1994 Nov;152(5 Pt 2):1850–1857. doi: 10.1016/s0022-5347(17)32399-6. [DOI] [PubMed] [Google Scholar]

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