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. 1996 Sep;64(9):3937–3941. doi: 10.1128/iai.64.9.3937-3941.1996

Apoptosis of lymphocytes in mice induced by infection with Rickettsia tsutsugamushi.

S Kasuya 1, I Nagano 1, T Ikeda 1, C Goto 1, K Shimokawa 1, Y Takahashi 1
PMCID: PMC174319  PMID: 8751955

Abstract

Histological examinations of mice infected with either a lethal (Karp) or a self-limitating (Gilliam) strain of Rickettsia tsutsugamushi were performed. Tingible body macrophages in the spleen and necrotizing lymphadenitis in regional lymph nodes were prominent only in the former. Apoptotic legions in the lymphocytes of these organs were clearly demonstrated by histochemical and electron microscopical examinations.

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Selected References

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