Abstract
This review discusses recent advances in the understanding of how the common pathogen, uropathogenic Escherichia coli, interacts with the host to lead to infection.
Full Text
The Full Text of this article is available as a PDF (66.4 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Abraham S., Shin J., Malaviya R. Type 1 fimbriated Escherichia coli-mast cell interactions in cystitis. J Infect Dis. 2001 Mar 1;183 (Suppl 1):S51–S55. doi: 10.1086/318853. [DOI] [PubMed] [Google Scholar]
- Cass A. S., Ireland G. W. Antibacterial perineal washing for prevention of recurrent urinary tract infections. Urology. 1985 May;25(5):492–494. doi: 10.1016/0090-4295(85)90458-3. [DOI] [PubMed] [Google Scholar]
- Fennell R. S., Wilson S. G., Garin E. H., Pryor N. D., Sorgen C. D., Walker R. D., Richard G. A. Bacteriuria in families of girls with recurrent bacteriuria. A survey of 112 family members showed similar infections in 14% of the female siblings. Clin Pediatr (Phila) 1977 Dec;16(12):1132–1135. doi: 10.1177/000992287701601211. [DOI] [PubMed] [Google Scholar]
- Ganz Tomas. Defensins: antimicrobial peptides of innate immunity. Nat Rev Immunol. 2003 Sep;3(9):710–720. doi: 10.1038/nri1180. [DOI] [PubMed] [Google Scholar]
- Goluszko P., Moseley S. L., Truong L. D., Kaul A., Williford J. R., Selvarangan R., Nowicki S., Nowicki B. Development of experimental model of chronic pyelonephritis with Escherichia coli O75:K5:H-bearing Dr fimbriae: mutation in the dra region prevented tubulointerstitial nephritis. J Clin Invest. 1997 Apr 1;99(7):1662–1672. doi: 10.1172/JCI119329. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hagberg L., Hull R., Hull S., McGhee J. R., Michalek S. M., Svanborg Edén C. Difference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN mice. Infect Immun. 1984 Dec;46(3):839–844. doi: 10.1128/iai.46.3.839-844.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hedges S. R., Agace W. W., Svanborg C. Epithelial cytokine responses and mucosal cytokine networks. Trends Microbiol. 1995 Jul;3(7):266–270. doi: 10.1016/s0966-842x(00)88941-6. [DOI] [PubMed] [Google Scholar]
- Hooton T. M., Scholes D., Hughes J. P., Winter C., Roberts P. L., Stapleton A. E., Stergachis A., Stamm W. E. A prospective study of risk factors for symptomatic urinary tract infection in young women. N Engl J Med. 1996 Aug 15;335(7):468–474. doi: 10.1056/NEJM199608153350703. [DOI] [PubMed] [Google Scholar]
- Hull R. A., Gill R. E., Hsu P., Minshew B. H., Falkow S. Construction and expression of recombinant plasmids encoding type 1 or D-mannose-resistant pili from a urinary tract infection Escherichia coli isolate. Infect Immun. 1981 Sep;33(3):933–938. doi: 10.1128/iai.33.3.933-938.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Langermann S., Möllby R., Burlein J. E., Palaszynski S. R., Auguste C. G., DeFusco A., Strouse R., Schenerman M. A., Hultgren S. J., Pinkner J. S. Vaccination with FimH adhesin protects cynomolgus monkeys from colonization and infection by uropathogenic Escherichia coli. J Infect Dis. 2000 Feb;181(2):774–778. doi: 10.1086/315258. [DOI] [PubMed] [Google Scholar]
- Lomberg H., Hanson L. A., Jacobsson B., Jodal U., Leffler H., Edén C. S. Correlation of P blood group, vesicoureteral reflux, and bacterial attachment in patients with recurrent pyelonephritis. N Engl J Med. 1983 May 19;308(20):1189–1192. doi: 10.1056/NEJM198305193082003. [DOI] [PubMed] [Google Scholar]
- Menestrina G., Pederzolli C., Dalla Serra M., Bregante M., Gambale F. Permeability increase induced by Escherichia coli hemolysin A in human macrophages is due to the formation of ionic pores: a patch clamp characterization. J Membr Biol. 1996 Jan;149(2):113–121. doi: 10.1007/s002329900012. [DOI] [PubMed] [Google Scholar]
- Mulvey M. A., Schilling J. D., Hultgren S. J. Establishment of a persistent Escherichia coli reservoir during the acute phase of a bladder infection. Infect Immun. 2001 Jul;69(7):4572–4579. doi: 10.1128/IAI.69.7.4572-4579.2001. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Plos K., Connell H., Jodal U., Marklund B. I., Mårild S., Wettergren B., Svanborg C. Intestinal carriage of P fimbriated Escherichia coli and the susceptibility to urinary tract infection in young children. J Infect Dis. 1995 Mar;171(3):625–631. doi: 10.1093/infdis/171.3.625. [DOI] [PubMed] [Google Scholar]
- Raz R., Stamm W. E. A controlled trial of intravaginal estriol in postmenopausal women with recurrent urinary tract infections. N Engl J Med. 1993 Sep 9;329(11):753–756. doi: 10.1056/NEJM199309093291102. [DOI] [PubMed] [Google Scholar]
- Reid G., Bruce A. W. Urogenital infections in women: can probiotics help? Postgrad Med J. 2003 Aug;79(934):428–432. doi: 10.1136/pmj.79.934.428. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts J. A., Suarez G. M., Kaack B., Kallenius G., Svenson S. B. Experimental pyelonephritis in the monkey. VII. Ascending pyelonephritis in the absence of vesicoureteral reflux. J Urol. 1985 Jun;133(6):1068–1075. doi: 10.1016/s0022-5347(17)49382-7. [DOI] [PubMed] [Google Scholar]
- Roberts James A., Kaack M. Bernice, Baskin Gary, Chapman Matthew R., Hunstad David A., Pinkner Jerome S., Hultgren Scott J. Antibody responses and protection from pyelonephritis following vaccination with purified Escherichia coli PapDG protein. J Urol. 2004 Apr;171(4):1682–1685. doi: 10.1097/01.ju.0000116123.05160.43. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Russo T. A., Carlino U. B., Johnson J. R. Identification of a new iron-regulated virulence gene, ireA, in an extraintestinal pathogenic isolate of Escherichia coli. Infect Immun. 2001 Oct;69(10):6209–6216. doi: 10.1128/IAI.69.10.6209-6216.2001. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sobel Jack D. Estrogen Replacement Therapy to Prevent Recurrent Urinary Tract Infection in Postmenopausal Women. Curr Infect Dis Rep. 2003 Dec;5(6):479–480. doi: 10.1007/s11908-003-0090-y. [DOI] [PubMed] [Google Scholar]
- Svanborg-Edén C., Svennerholm A. M. Secretory immunoglobulin A and G antibodies prevent adhesion of Escherichia coli to human urinary tract epithelial cells. Infect Immun. 1978 Dec;22(3):790–797. doi: 10.1128/iai.22.3.790-797.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Underdown B. J., Schiff J. M. Immunoglobulin A: strategic defense initiative at the mucosal surface. Annu Rev Immunol. 1986;4:389–417. doi: 10.1146/annurev.iy.04.040186.002133. [DOI] [PubMed] [Google Scholar]