Skip to main content
Sexually Transmitted Infections logoLink to Sexually Transmitted Infections
. 2003 Feb;79(1):22–27. doi: 10.1136/sti.79.1.22

Opportunistic screening for genital chlamydial infection. II: Prevalence among healthcare attenders, outcome, and evaluation of positive cases

J Pimenta 1, M Catchpole 1, P Rogers 1, J Hopwood 1, S Randall 1, H Mallinson 1, E Perkins 1, N Jackson 1, C Carlisle 1, G Hewitt 1, G Underhill 1, T Gleave 1, L McLean 1, A Ghosh 1, J Tobin 1, V Harindra 1
PMCID: PMC1744609  PMID: 12576608

Abstract

Objectives: To determine the prevalence and treatment outcomes among young women screened opportunistically for genital Chlamydia trachomatis and to evaluate the impact of screening in those participating.

Design: An opportunistic screening programme (1 September 1999 to 31 August 2000) using urine samples, tested by ligase chain reaction (LCR). In-depth interviews were used for programme evaluation.

Setting: Screening was offered in two health authorities at general practice, family planning, genitourinary medicine (GUM), adolescent sexual health, termination of pregnancy clinics and women's services in hospitals (antenatal, colposcopy, gynaecology and infertility clinics).

Main participants: Sexually active women (16–24 years) attending for any reason.

Main outcome measures: Screening data: prevalence of infection by age and healthcare setting; proportion of positive patients attending for treatment. Evaluation data: participants' attitudes and views towards screening and follow up.

Results: In total, 16 930 women (16–24 years) were screened. Prevalence was higher in younger women (16–20) than those aged 21–24 years and was highly variable at different healthcare settings (range 3.4%–17.6%). Prevalence was approximately 9% in general practice. The role of the project health advisers in managing results and coordinating treatment of positive individuals was essential; the vast majority of all positives were known to be treated. Women felt that screening was beneficial. Improving awareness and education about sexually transmitted infections is required to alleviate negative reactions associated with testing positive for infection.

Conclusions: Prevalence of infection outside GUM clinics is substantial and opportunistic screening using urine samples is an acceptable method of reaching individuals with infection who do not normally present at specialist clinics.

Full Text

The Full Text of this article is available as a PDF (142.6 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chernesky M. A., Jang D., Lee H., Burczak J. D., Hu H., Sellors J., Tomazic-Allen S. J., Mahony J. B. Diagnosis of Chlamydia trachomatis infections in men and women by testing first-void urine by ligase chain reaction. J Clin Microbiol. 1994 Nov;32(11):2682–2685. doi: 10.1128/jcm.32.11.2682-2685.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Djuretic T., Catchpole M., Bingham J. S., Robinson A., Hughes G., Kinghorn G. Genitourinary medicine services in the United Kingdom are failing to meet current demand. Int J STD AIDS. 2001 Sep;12(9):571–572. doi: 10.1258/0956462011923732. [DOI] [PubMed] [Google Scholar]
  3. Dryden M. S., Wilkinson M., Redman M., Millar M. R. Detection of Chlamydia trachomatis in general practice urine samples. Br J Gen Pract. 1994 Mar;44(380):114–117. [PMC free article] [PubMed] [Google Scholar]
  4. Duncan B., Hart G., Scoular A., Bigrigg A. Qualitative analysis of psychosocial impact of diagnosis of Chlamydia trachomatis: implications for screening. BMJ. 2001 Jan 27;322(7280):195–199. doi: 10.1136/bmj.322.7280.195. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. France C., Thomas K., Slack R., James N. Psychosocial impacts of chlamydia testing are important. BMJ. 2001 May 19;322(7296):1245–1245. [PMC free article] [PubMed] [Google Scholar]
  6. Harvey J., Webb A., Mallinson H. Chlamydia trachomatis screening in young people in Merseyside. Br J Fam Plann. 2000 Oct;26(4):199–201. [PubMed] [Google Scholar]
  7. Johnson A. M., Mercer C. H., Erens B., Copas A. J., McManus S., Wellings K., Fenton K. A., Korovessis C., Macdowall W., Nanchahal K. Sexual behaviour in Britain: partnerships, practices, and HIV risk behaviours. Lancet. 2001 Dec 1;358(9296):1835–1842. doi: 10.1016/S0140-6736(01)06883-0. [DOI] [PubMed] [Google Scholar]
  8. Macmillan S., McKenzie H., Flett G., Templeton A. Which women should be tested for Chlamydia trachomatis? BJOG. 2000 Sep;107(9):1088–1093. doi: 10.1111/j.1471-0528.2000.tb11105.x. [DOI] [PubMed] [Google Scholar]
  9. Pimenta J. M., Catchpole M., Rogers P. A., Perkins E., Jackson N., Carlisle C., Randall S., Hopwood J., Hewitt G., Underhill G. Opportunistic screening for genital chlamydial infection. I: acceptability of urine testing in primary and secondary healthcare settings. Sex Transm Infect. 2003 Feb;79(1):16–21. doi: 10.1136/sti.79.1.16. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Rogstad K. E., Davies A., Murthy S. K., Searle S., Mee R. A. The management of Chlamydia trachomatis: combined community and hospital study. Sex Transm Infect. 2000 Dec;76(6):493–494. doi: 10.1136/sti.76.6.493. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Ross J. D., Sutherland S., Coia J. Genital Chlamydia trachomatis infections in primary care. BMJ. 1996 Nov 9;313(7066):1192–1193. doi: 10.1136/bmj.313.7066.1192a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Tobin J. M., Bateman J., Banks B., Jeffs J. Clinical audit of the process of referral to genitourinary medicine of patients found to be chlamydia positive in a family planning service. Br J Fam Plann. 1999 Jan;24(4):160–163. [PubMed] [Google Scholar]

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

[Corrected Table 3]
straninf_79_1_22__1.pdf (17.9KB, pdf)

Articles from Sexually Transmitted Infections are provided here courtesy of BMJ Publishing Group

RESOURCES