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. 1996 Nov;64(11):4872–4875. doi: 10.1128/iai.64.11.4872-4875.1996

Growth of Chlamydia pneumoniae induces cytokine production and expression of CD14 in a human monocytic cell line.

M Heinemann 1, M Susa 1, U Simnacher 1, R Marre 1, A Essig 1
PMCID: PMC174462  PMID: 8890256

Abstract

Chlamydia pneumoniae was able to survive and to multiply in the human monocytic cell line Mono Mac 6. Growth of C. pneumoniae induced production of tumor necrosis factor alpha, interleukin 1beta, and interleukin 6, as well as up-regulation of the CD14 molecule in a time-dependent manner. Infection of monocytic cells and a proinflammatory cytokine response may be important in C. pneumoniae pathogenesis.

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Selected References

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