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. 2004 Aug;80(4):264–271. doi: 10.1136/sti.2004.010389

Surveillance systems for STIs in the European Union: facing a changing epidemiology

C Lowndes 1, K Fenton 1
PMCID: PMC1744868  PMID: 15295122

Abstract

Methods: Cross sectional survey using a structured questionnaire.

Results: Case reporting from clinicians and/or laboratories is the mainstay of EU surveillance systems for bacterial STIs. Coverage of case reporting varies from less than 10% to over 75%, and lack of and/or heterogeneity in case definitions affect the relative specificity and sensitivity of reporting systems. Considerable variations also exist in STI care sites; the populations who use these services; and in partner notification practices, STI screening practices, and STI laboratory diagnostic tests employed, affecting the representativeness of reported data and the sensitivity of surveillance systems for detecting the true number of STI cases.

Conclusions: The heterogeneity of current surveillance systems complicates direct comparison of STI incidence rates across Europe. Introduction of standardised case definitions for reporting, and increased coverage of mandatory reporting systems where necessary, are needed. Definition of standardised minimum datasets and use of sentinel and enhanced surveillance systems to supplement universal case/laboratory notification data, could improve our understanding of the distribution and determinants of STIs across Europe, and aid in the design of effective public health responses. In the context of the changing epidemiology of STIs, systems for detection and monitoring of localised outbreaks of acute bacterial STIs (syphilis and antimicrobial resistant gonorrhoea), as well as prevalence monitoring systems for frequently asymptomatic STIs (chlamydial infection and viral STIs), are also necessary.

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Selected References

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  1. Bell A., Ncube F., Hansell A., Davison K. L., Young Y., Gilson R., Macdonald N., Heathcock R., Warburton F., Maguire H. An outbreak of hepatitis A among young men associated with having sex in public venues. Commun Dis Public Health. 2001 Sep;4(3):163–170. [PubMed] [Google Scholar]
  2. Berglund Torsten, Unemo Magnus, Olcén Per, Giesecke Johan, Fredlund Hans. One year of Neisseria gonorrhoeae isolates in Sweden: the prevalence study of antibiotic susceptibility shows relation to the geographic area of exposure. Int J STD AIDS. 2002 Feb;13(2):109–114. doi: 10.1258/0956462021924730. [DOI] [PubMed] [Google Scholar]
  3. Bingham J. S. Services for sexually transmitted infections in Europe and central Asia. Sex Transm Infect. 2002 Oct;78(5):320–321. doi: 10.1136/sti.78.5.320. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bovée L. P., Peerbooms P. G., van den Hoek J. A. Shigellose, een seksueel overdraagbare aandoening bij homoseksuele mannen. Ned Tijdschr Geneeskd. 2003 Dec 6;147(49):2438–2439. [PubMed] [Google Scholar]
  5. Catchpole M. A. The role of epidemiology and surveillance systems in the control of sexually transmitted diseases. Genitourin Med. 1996 Oct;72(5):321–329. doi: 10.1136/sti.72.5.321. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Coenen A. J. J., Berends R., Van der Meijden W. I. The organization of STI control in the Netherlands - an overview. Int J STD AIDS. 2002 Apr;13(4):254–260. doi: 10.1258/0956462021925054. [DOI] [PubMed] [Google Scholar]
  7. Dal Conte I., Lucchini A., Contuzzi E., Di Perri G., Bingham J. Sexually transmitted infections in Italy: an overview. Int J STD AIDS. 2001 Dec;12(12):813–818. doi: 10.1258/0956462011924452. [DOI] [PubMed] [Google Scholar]
  8. Dehne K. L., Riedner G., Neckermann C., Mykyev O., Ndowa F. J., Laukamm-Josten U. A survey of STI policies and programmes in Europe: preliminary results. Sex Transm Infect. 2002 Oct;78(5):380–384. doi: 10.1136/sti.78.5.380. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Desenclos J. C., Bijkerk H., Huisman J. Variations in national infectious diseases surveillance in Europe. Lancet. 1993 Apr 17;341(8851):1003–1006. doi: 10.1016/0140-6736(93)91084-y. [DOI] [PubMed] [Google Scholar]
  10. Fenton K. A., Lowndes C. M. Recent trends in the epidemiology of sexually transmitted infections in the European Union. Sex Transm Infect. 2004 Aug;80(4):255–263. doi: 10.1136/sti.2004.009415. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Fenton K., Giesecke J., Hamers F. F. Europe-wide surveillance for sexually transmitted infections: a timely and appropriate intervention. Euro Surveill. 2001 May;6(5):69–70. doi: 10.2807/esm.06.05.00207-en. [DOI] [PubMed] [Google Scholar]
  12. Fenton Kevin A., Ison Catherine, Johnson Alan P., Rudd Elizabeth, Soltani Mehnam, Martin Iona, Nichols Tom, Livermore David M., GRASP collaboration Ciprofloxacin resistance in Neisseria gonorrhoeae in England and Wales in 2002. Lancet. 2003 May 31;361(9372):1867–1869. doi: 10.1016/S0140-6736(03)13489-7. [DOI] [PubMed] [Google Scholar]
  13. Ferreira E., Louro D., Gomes J. P., Catry M. A., Pato M. V. High-level tetracycline resistant Neisseria gonorrhoeae isolated in Portugal. Pathol Biol (Paris) 1997 May;45(5):371–375. [PubMed] [Google Scholar]
  14. Greco D., Giuliani M., Suligoi B., Panatta M., Giannetti A. Sexually transmitted diseases in Italy: clinical returns versus statutory notifications. Genitourin Med. 1990 Oct;66(5):383–386. doi: 10.1136/sti.66.5.383. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Götz Hannelore, Lindback Johan, Ripa Torvald, Arneborn Malin, Ramsted Kristina, Ekdahl Karl. Is the increase in notifications of Chlamydia trachomatis infections in Sweden the result of changes in prevalence, sampling frequency or diagnostic methods? Scand J Infect Dis. 2002;34(1):28–34. doi: 10.1080/00365540110077001. [DOI] [PubMed] [Google Scholar]
  16. Hiltunen-Back E., Haikala O., Kautiainen H., Paavonen J., Reunala T. A nationwide sentinel clinic survey of chlamydia trachomatis infection in Finland. Sex Transm Dis. 2001 May;28(5):252–258. doi: 10.1097/00007435-200105000-00002. [DOI] [PubMed] [Google Scholar]
  17. Hoffmann S. The laboratory surveillance system of Chlamydia trachomatis and Neisseria gonorrhoeae infections in Denmark. Euro Surveill. 2001 May;6(5):86–90. doi: 10.2807/esm.06.05.00211-en. [DOI] [PubMed] [Google Scholar]
  18. Hughes G., Paine T., Thomas D. Surveillance of sexually transmitted infections in England and Wales. Euro Surveill. 2001 May;6(5):71–80. doi: 10.2807/esm.06.05.00208-en. [DOI] [PubMed] [Google Scholar]
  19. Koutsky Laura A., Ault Kevin A., Wheeler Cosette M., Brown Darron R., Barr Eliav, Alvarez Frances B., Chiacchierini Lisa M., Jansen Kathrin U., Proof of Principle Study Investigators A controlled trial of a human papillomavirus type 16 vaccine. N Engl J Med. 2002 Nov 21;347(21):1645–1651. doi: 10.1056/NEJMoa020586. [DOI] [PubMed] [Google Scholar]
  20. Massari Véronique, Retel Olivier, Flahault Antoine. A recent increase in the incidence of male urethritis in France. Sex Transm Dis. 2002 Jun;29(6):319–323. doi: 10.1097/00007435-200206000-00002. [DOI] [PubMed] [Google Scholar]
  21. Mavroidi A., Tzouvelekis L. S., Kyriakis K. P., Avgerinou H., Daniilidou M., Tzelepi E. Multidrug-resistant strains of Neisseria gonorrhoeae in Greece. Antimicrob Agents Chemother. 2001 Sep;45(9):2651–2654. doi: 10.1128/AAC.45.9.2651-2654.2001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Meyer L., Goulet V., Massari V., Lepoutre-Toulemon A. Surveillance of sexually transmitted diseases in France: recent trends and incidence. Genitourin Med. 1994 Feb;70(1):15–21. doi: 10.1136/sti.70.1.15. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Moi H. Care of sexually transmitted infections in the Nordic countries. Int J STD AIDS. 2001 Dec;12(12):819–823. doi: 10.1258/0956462011924326. [DOI] [PubMed] [Google Scholar]
  24. Mårdh P. A. Improvement of surveillance programs for sexually transmitted infections and related conditions. Eur J Contracept Reprod Health Care. 1998 Sep;3(3):136–146. doi: 10.3109/13625189809051417. [DOI] [PubMed] [Google Scholar]
  25. Mårdh P. A. Limitations of current surveillance programs for sexually transmitted infections and allied conditions affecting reproductive health care. Eur J Contracept Reprod Health Care. 1998 Sep;3(3):147–154. doi: 10.3109/13625189809051418. [DOI] [PubMed] [Google Scholar]
  26. Møller J. K., Andersen B., Olesen F., Ostergaard L. Reasons for Chlamydia trachomatis testing and the associated age-specific prevalences. Scand J Clin Lab Invest. 2003;63(5):339–345. doi: 10.1080/00365510310002031. [DOI] [PubMed] [Google Scholar]
  27. Nicoll Angus, Hamers Françoise F. Are trends in HIV, gonorrhoea, and syphilis worsening in western Europe? BMJ. 2002 Jun 1;324(7349):1324–1327. doi: 10.1136/bmj.324.7349.1324. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Nissinen A., Järvinen H., Liimatainen O., Jahkola M., Huovinen P. Antimicrobial resistance in Neisseria gonorrhoeae in Finland, 1976 to 1995. The Finnish Study Group For Antimicrobial Resistance. Sex Transm Dis. 1997 Nov;24(10):576–581. doi: 10.1097/00007435-199711000-00005. [DOI] [PubMed] [Google Scholar]
  29. Panchaud C., Singh S., Feivelson D., Darroch J. E. Sexually transmitted diseases among adolescents in developed countries. Fam Plann Perspect. 2000 Jan-Feb;32(1):24-32, 45. [PubMed] [Google Scholar]
  30. Petzoldt D., Jappe U., Hartmann M., Hamouda O. Sexually transmitted diseases in Germany. Int J STD AIDS. 2002 Apr;13(4):246–253. doi: 10.1258/0956462021925045. [DOI] [PubMed] [Google Scholar]
  31. Reintjes R., Bosman A., de Zwart O., Stevens M., van der Knaap L., van den Hoek K. Outbreak of hepatitis A in Rotterdam associated with visits to 'darkrooms' in gay bars. Commun Dis Public Health. 1999 Jan;2(1):43–46. [PubMed] [Google Scholar]
  32. Simms I., Hurtig A-K, Rogers P. A., Hughes G., Fenton K. A. Surveillance of sexually transmitted infections in primary care. Sex Transm Infect. 2003 Jun;79(3):174–176. doi: 10.1136/sti.79.3.174. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Stanberry Lawrence R., Spruance Spotswood L., Cunningham Anthony L., Bernstein David I., Mindel Adrian, Sacks Stephen, Tyring Stephen, Aoki Fred Y., Slaoui Moncef, Denis Martine. Glycoprotein-D-adjuvant vaccine to prevent genital herpes. N Engl J Med. 2002 Nov 21;347(21):1652–1661. doi: 10.1056/NEJMoa011915. [DOI] [PubMed] [Google Scholar]
  34. Stene-Johansen K., Jenum P. A., Hoel T., Blystad H., Sunde H., Skaug K. An outbreak of hepatitis A among homosexuals linked to a family outbreak. Epidemiol Infect. 2002 Aug;129(1):113–117. doi: 10.1017/s0950268802007069. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Tzelepi E., Avgerinou H., Kyriakis K. P., Tzouvelekis L. S., Flemetakis A., Kalogeropoulou A., Frangouli E. Antimicrobial susceptibility and types of Neisseria gonorrhoeae in Greece. Data for the period 1990 to 1993. Sex Transm Dis. 1997 Jul;24(6):378–385. doi: 10.1097/00007435-199707000-00012. [DOI] [PubMed] [Google Scholar]
  36. van den Hoek J. A., Mulder-Folkerts D. K., Coutinho R. A., Dukers N. H., Buimer M., van Doornum G. J. Opportunistische screening op genitale infecties met Chlamydia trachomatis onder de seksueel actieve bevolking in Amsterdam. I. Meer dan 90% deelname en bijna 5% prevalentie. Ned Tijdschr Geneeskd. 1999 Mar 27;143(13):668–672. [PubMed] [Google Scholar]

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