Skip to main content
PMC home page
Thorax logoLink to Thorax
. 2000 Oct;55(10):878–881. doi: 10.1136/thorax.55.10.878

Allergic inflammation in the unified airway: start with the nose

B Lipworth 1, P White 1
PMCID: PMC1745607  PMID: 10992543

Full Text

The Full Text of this article is available as a PDF (136.0 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. American Thoracic Society Workshop. Immunobiology of asthma and rhinitis. Pathogenic factors and therapeutic options. Am J Respir Crit Care Med. 1999 Nov;160(5 Pt 1):1778–1787. doi: 10.1164/ajrccm.160.5.ats7-99. [DOI] [PubMed] [Google Scholar]
  2. Aubier M., Levy J., Clerici C., Neukirch F., Herman D. Different effects of nasal and bronchial glucocorticosteroid administration on bronchial hyperresponsiveness in patients with allergic rhinitis. Am Rev Respir Dis. 1992 Jul;146(1):122–126. doi: 10.1164/ajrccm/146.1.122. [DOI] [PubMed] [Google Scholar]
  3. Bolger W. E., Butzin C. A., Parsons D. S. Paranasal sinus bony anatomic variations and mucosal abnormalities: CT analysis for endoscopic sinus surgery. Laryngoscope. 1991 Jan;101(1 Pt 1):56–64. doi: 10.1288/00005537-199101000-00010. [DOI] [PubMed] [Google Scholar]
  4. Chanez P., Vignola A. M., Vic P., Guddo F., Bonsignore G., Godard P., Bousquet J. Comparison between nasal and bronchial inflammation in asthmatic and control subjects. Am J Respir Crit Care Med. 1999 Feb;159(2):588–595. doi: 10.1164/ajrccm.159.2.9801022. [DOI] [PubMed] [Google Scholar]
  5. Corren J., Adinoff A. D., Buchmeier A. D., Irvin C. G. Nasal beclomethasone prevents the seasonal increase in bronchial responsiveness in patients with allergic rhinitis and asthma. J Allergy Clin Immunol. 1992 Aug;90(2):250–256. doi: 10.1016/0091-6749(92)90079-h. [DOI] [PubMed] [Google Scholar]
  6. Corren J. Allergic rhinitis and asthma: how important is the link? J Allergy Clin Immunol. 1997 Feb;99(2):S781–S786. doi: 10.1016/s0091-6749(97)70127-1. [DOI] [PubMed] [Google Scholar]
  7. Durham S. R., Walker S. M., Varga E. M., Jacobson M. R., O'Brien F., Noble W., Till S. J., Hamid Q. A., Nouri-Aria K. T. Long-term clinical efficacy of grass-pollen immunotherapy. N Engl J Med. 1999 Aug 12;341(7):468–475. doi: 10.1056/NEJM199908123410702. [DOI] [PubMed] [Google Scholar]
  8. East C. A., Annis J. A. Preoperative CT scanning for endoscopic sinus surgery: a rational approach. Clin Otolaryngol Allied Sci. 1992 Feb;17(1):60–66. doi: 10.1111/j.1365-2273.1992.tb00990.x. [DOI] [PubMed] [Google Scholar]
  9. Foresi A., Leone C., Pelucchi A., Mastropasqua B., Chetta A., D'Ippolito R., Marazzini L., Olivieri D. Eosinophils, mast cells, and basophils in induced sputum from patients with seasonal allergic rhinitis and perennial asthma: relationship to methacholine responsiveness. J Allergy Clin Immunol. 1997 Jul;100(1):58–64. doi: 10.1016/s0091-6749(97)70195-7. [DOI] [PubMed] [Google Scholar]
  10. Foresi A., Pelucchi A., Gherson G., Mastropasqua B., Chiapparino A., Testi R. Once daily intranasal fluticasone propionate (200 micrograms) reduces nasal symptoms and inflammation but also attenuates the increase in bronchial responsiveness during the pollen season in allergic rhinitis. J Allergy Clin Immunol. 1996 Aug;98(2):274–282. doi: 10.1016/s0091-6749(96)70150-1. [DOI] [PubMed] [Google Scholar]
  11. Havas T. E., Motbey J. A., Gullane P. J. Prevalence of incidental abnormalities on computed tomographic scans of the paranasal sinuses. Arch Otolaryngol Head Neck Surg. 1988 Aug;114(8):856–859. doi: 10.1001/archotol.1988.01860200040012. [DOI] [PubMed] [Google Scholar]
  12. Henriksen A. H., Sue-Chu M., Holmen T. L., Langhammer A., Bjermer L. Exhaled and nasal NO levels in allergic rhinitis: relation to sensitization, pollen season and bronchial hyperresponsiveness. Eur Respir J. 1999 Feb;13(2):301–306. doi: 10.1034/j.1399-3003.1999.13b14.x. [DOI] [PubMed] [Google Scholar]
  13. Henriksen J. M., Wenzel A. Effect of an intranasally administered corticosteroid (budesonide) on nasal obstruction, mouth breathing, and asthma. Am Rev Respir Dis. 1984 Dec;130(6):1014–1018. doi: 10.1164/arrd.1984.130.6.1014. [DOI] [PubMed] [Google Scholar]
  14. Howarth P. H., Stern M. A., Roi L., Reynolds R., Bousquet J. Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine hydrochloride (120 and 180 mg once daily) and cetirizine in seasonal allergic rhinitis. J Allergy Clin Immunol. 1999 Nov;104(5):927–933. doi: 10.1016/s0091-6749(99)70070-9. [DOI] [PubMed] [Google Scholar]
  15. Lamblin C., Gosset P., Salez F., Vandezande L. M., Perez T., Darras J., Janin A., Tonnel A. B., Wallaert B. Eosinophilic airway inflammation in nasal polyposis. J Allergy Clin Immunol. 1999 Jul;104(1):85–92. doi: 10.1016/s0091-6749(99)70118-1. [DOI] [PubMed] [Google Scholar]
  16. McNeely W., Wiseman L. R. Intranasal azelastine. A review of its efficacy in the management of allergic rhinitis. Drugs. 1998 Jul;56(1):91–114. doi: 10.2165/00003495-199856010-00011. [DOI] [PubMed] [Google Scholar]
  17. Meltzer E. O., Malmstrom K., Lu S., Prenner B. M., Wei L. X., Weinstein S. F., Wolfe J. D., Reiss T. F. Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis: a randomized, placebo-controlled clinical trial. J Allergy Clin Immunol. 2000 May;105(5):917–922. doi: 10.1067/mai.2000.106040. [DOI] [PubMed] [Google Scholar]
  18. Pullerits T., Praks L., Skoogh B. E., Ani R., Lötvall J. Randomized placebo-controlled study comparing a leukotriene receptor antagonist and a nasal glucocorticoid in seasonal allergic rhinitis. Am J Respir Crit Care Med. 1999 Jun;159(6):1814–1818. doi: 10.1164/ajrccm.159.6.9810016. [DOI] [PubMed] [Google Scholar]
  19. Reed C. E., Marcoux J. P., Welsh P. W. Effects of topical nasal treatment on asthma symptoms. J Allergy Clin Immunol. 1988 May;81(5 Pt 2):1042–1047. doi: 10.1016/0091-6749(88)90177-7. [DOI] [PubMed] [Google Scholar]
  20. Roquet A., Dahlén B., Kumlin M., Ihre E., Anstrén G., Binks S., Dahlén S. E. Combined antagonism of leukotrienes and histamine produces predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics. Am J Respir Crit Care Med. 1997 Jun;155(6):1856–1863. doi: 10.1164/ajrccm.155.6.9196086. [DOI] [PubMed] [Google Scholar]
  21. Settipane G. A. Epidemiology of nasal polyps. Allergy Asthma Proc. 1996 Sep-Oct;17(5):231–236. doi: 10.2500/108854196778662246. [DOI] [PubMed] [Google Scholar]
  22. Simons F. E. Is antihistamine (H1-receptor antagonist) therapy useful in clinical asthma? Clin Exp Allergy. 1999 Jul;29 (Suppl 3):98–104. doi: 10.1046/j.1365-2222.1999.0290s3098.x. [DOI] [PubMed] [Google Scholar]
  23. White P. S., Maclennan A. C., Connolly A. A., Crowther J., Bingham B. J. Analysis of CT scanning referrals for chronic rhinosinusitis. J Laryngol Otol. 1996 Jul;110(7):641–643. [PubMed] [Google Scholar]
  24. Wilson A., Dempsey O. J., Sims E. J., Coutie W. J., Paterson M. C., Lipworth B. J. Evaluation of treatment response in patients with seasonal allergic rhinitis using domiciliary nasal peak inspiratory flow. Clin Exp Allergy. 2000 Jun;30(6):833–838. doi: 10.1046/j.1365-2222.2000.00749.x. [DOI] [PubMed] [Google Scholar]
  25. Wood R. A., Eggleston P. A. The effects of intranasal steroids on nasal and pulmonary responses to cat exposure. Am J Respir Crit Care Med. 1995 Feb;151(2 Pt 1):315–320. doi: 10.1164/ajrccm.151.2.7842184. [DOI] [PubMed] [Google Scholar]
  26. Woodcock A., Custovic A. ABC of allergies. Avoiding exposure to indoor allergens. BMJ. 1998 Apr 4;316(7137):1075–1078. doi: 10.1136/bmj.316.7137.1075. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Zinreich S. J., Kennedy D. W., Rosenbaum A. E., Gayler B. W., Kumar A. J., Stammberger H. Paranasal sinuses: CT imaging requirements for endoscopic surgery. Radiology. 1987 Jun;163(3):769–775. doi: 10.1148/radiology.163.3.3575731. [DOI] [PubMed] [Google Scholar]

Articles from Thorax are provided here courtesy of BMJ Publishing Group

RESOURCES