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. 2000 Feb;55(2):97–101. doi: 10.1136/thorax.55.2.97

Emergency pre-hospital management of patients admitted with acute asthma

A Simpson 1, S Matusiewicz 1, P Brown 1, I McCall 1, J Innes 1, A Greening 1, G Crompton 1
PMCID: PMC1745682  PMID: 10639524

Abstract

BACKGROUND—Little is known about the management of acute asthma prior to hospital admission. Pre-hospital treatment of patients referred to hospital with acute asthma was therefore studied in 150 patients divided into three groups: those in the Edinburgh Emergency Asthma Admission Service (EEAAS) who can contact an ambulance and present directly to respiratory services when symptoms arise (n = 38), those under continuing supervision at a hospital respiratory outpatient clinic (n = 54), and those managed solely in primary care (n =58).
METHODS—Standardised admission forms detailing aspects of pre-hospital management, case records, GP referral letters, and ambulance patient transport forms were analysed.
RESULTS—In each group airflow obstruction had improved upon arrival at hospital, the effect being most marked in patients transported by ambulance (p<0.001) and in those receiving nebulised β2 agonists prior to admission (p<0.005). However, 25% of patients arrived without having nebulised β2 agonists and 37% without having glucocorticoids. EEAAS patients were least likely to receive nebulised β2 agonists before arrival at hospital (p<0.05). This observation was attributable to a tendency for these patients to travel to hospital by car rather than by ambulance.
CONCLUSIONS—There is an important shortfall in administration of bronchodilators and glucocorticoids for acute asthma before arrival at hospital. Ambulances equipped with nebulised bronchodilators provide the optimal mode of transport to hospital for patients with acute asthma. In Edinburgh ambulances are not being used by a significant proportion of the population with asthma, possibly because of the mistaken belief that personal transport arrangements reduce journey time to hospital.



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Selected References

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  1. Campbell I. A., Colman S. B., Mao J. H., Prescott R. J., Weston C. F. An open, prospective comparison of beta 2 agonists given via nebuliser, Nebuhaler, or pressurised inhaler by ambulance crew as emergency treatment. Thorax. 1995 Jan;50(1):79–80. doi: 10.1136/thx.50.1.79. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Corbridge T. C., Hall J. B. The assessment and management of adults with status asthmaticus. Am J Respir Crit Care Med. 1995 May;151(5):1296–1316. doi: 10.1164/ajrccm.151.5.7735578. [DOI] [PubMed] [Google Scholar]
  3. Crompton G. K., Grant I. W., Chapman B. J., Thomson A., McDonald C. F. Edinburgh Emergency Asthma Admission Service: report on 15 years' experience. Eur J Respir Dis. 1987 May;70(5):266–271. [PubMed] [Google Scholar]
  4. Crompton G. K., Grant I. W. Edinburgh emergency asthma admission service. Br Med J. 1975 Dec 20;4(5998):680–682. doi: 10.1136/bmj.4.5998.680. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Fergusson R. J., Stewart C. M., Wathen C. G., Moffat R., Crompton G. K. Effectiveness of nebulised salbutamol administered in ambulances to patients with severe acute asthma. Thorax. 1995 Jan;50(1):81–82. doi: 10.1136/thx.50.1.81. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Graham V. A., Milton A. F., Knowles G. K., Davies R. J. Routine antibiotics in hospital management of acute asthma. Lancet. 1982 Feb 20;1(8269):418–420. doi: 10.1016/s0140-6736(82)91619-1. [DOI] [PubMed] [Google Scholar]
  7. Kolbe J., Vamos M., Fergusson W., Elkind G., Garrett J. Differential influences on asthma self-management knowledge and self-management behavior in acute severe asthma. Chest. 1996 Dec;110(6):1463–1468. doi: 10.1378/chest.110.6.1463. [DOI] [PubMed] [Google Scholar]
  8. Lipworth B. J. Pharmacokinetics of inhaled drugs. Br J Clin Pharmacol. 1996 Dec;42(6):697–705. doi: 10.1046/j.1365-2125.1996.00493.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Littlejohns P., Hollowell J., Hayward P., Prance S. Comparison of asthmatic patients admitted to hospital from health districts experiencing high and low asthma mortality rates. Postgrad Med J. 1994 Feb;70(820):92–99. doi: 10.1136/pgmj.70.820.92. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Neville R. G., Clark R. C., Hoskins G., Smith B. National asthma attack audit 1991-2. General Practitioners in Asthma Group. BMJ. 1993 Feb 27;306(6877):559–562. doi: 10.1136/bmj.306.6877.559. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Neville R. G., Hoskins G., Smith B., Clark R. A. How general practitioners manage acute asthma attacks. Thorax. 1997 Feb;52(2):153–156. doi: 10.1136/thx.52.2.153. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Quadrel M., Lavery R. F., Jaker M., Atkin S., Tortella B. J., Cody R. P. Prospective, randomized trial of epinephrine, metaproterenol, and both in the prehospital treatment of asthma in the adult patient. Ann Emerg Med. 1995 Oct;26(4):469–473. doi: 10.1016/s0196-0644(95)70116-8. [DOI] [PubMed] [Google Scholar]
  13. Sears M. R., Rea H. H., Fenwick J., Gillies A. J., Holst P. E., O'Donnell T. V., Rothwell R. P. 75 deaths in asthmatics prescribed home nebulisers. Br Med J (Clin Res Ed) 1987 Feb 21;294(6570):477–480. doi: 10.1136/bmj.294.6570.477. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Sibbald B. Patient self care in acute asthma. Thorax. 1989 Feb;44(2):97–101. doi: 10.1136/thx.44.2.97. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Teichtahl H., Buckmaster N., Pertnikovs E. The incidence of respiratory tract infection in adults requiring hospitalization for asthma. Chest. 1997 Sep;112(3):591–596. doi: 10.1378/chest.112.3.591. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Wathen C. G., Crompton G. K., Carrington D., Hollingworth J. Treatment for acute asthma in the ambulance. Br J Gen Pract. 1990 Sep;40(338):388–388. [PMC free article] [PubMed] [Google Scholar]
  17. Weiss S. J., Anand P., Ernst A. A., Orgeron D., May W. L. Effect of out-of-hospital albuterol inhalation treatments on patient comfort and morbidity. Ann Emerg Med. 1994 Nov;24(5):873–878. doi: 10.1016/s0196-0644(94)70205-5. [DOI] [PubMed] [Google Scholar]
  18. Windom H. H., Burgess C. D., Crane J., Pearce N., Kwong T., Beasley R. The self-administration of inhaled beta agonist drugs during severe asthma. N Z Med J. 1990 May 9;103(889):205–207. [PubMed] [Google Scholar]
  19. Wong B. J., Hargreave F. E. Bioequivalence of metered-dose inhaled medications. J Allergy Clin Immunol. 1993 Sep;92(3):373–379. doi: 10.1016/0091-6749(93)90115-v. [DOI] [PubMed] [Google Scholar]

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