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. 2002 Nov;57(11):982–985. doi: 10.1136/thorax.57.11.982

Chronic obstructive pulmonary disease • 4: Imaging the lungs in patients with chronic obstructive pulmonary disease

N Muller 1, H Coxson 1
PMCID: PMC1746224  PMID: 12403883

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Selected References

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  1. Bae K. T., Slone R. M., Gierada D. S., Yusen R. D., Cooper J. D. Patients with emphysema: quantitative CT analysis before and after lung volume reduction surgery. Work in progress. Radiology. 1997 Jun;203(3):705–714. doi: 10.1148/radiology.203.3.9169692. [DOI] [PubMed] [Google Scholar]
  2. Bankier A. A., De Maertelaer V., Keyzer C., Gevenois P. A. Pulmonary emphysema: subjective visual grading versus objective quantification with macroscopic morphometry and thin-section CT densitometry. Radiology. 1999 Jun;211(3):851–858. doi: 10.1148/radiology.211.3.r99jn05851. [DOI] [PubMed] [Google Scholar]
  3. Bankier A. A., Fleischmann D., Mallek R., Windisch A., Winkelbauer F. W., Kontrus M., Havelec L., Herold C. J., Hübsch P. Bronchial wall thickness: appropriate window settings for thin-section CT and radiologic-anatomic correlation. Radiology. 1996 Jun;199(3):831–836. doi: 10.1148/radiology.199.3.8638013. [DOI] [PubMed] [Google Scholar]
  4. Bates D. V., Gordon C. A., Paul G. I., Place R. E., Snidal D. P., Woolf C. R. Chronic bronchitis. Report on the third and fourth stages of the co-ordinated study of chronic bronchitis in the Department of Veterans Affairs, Canada. Med Serv J Can. 1966 Jan;22(1):1–59. [PubMed] [Google Scholar]
  5. Bergin C. J., Müller N. L., Miller R. R. CT in the qualitative assessment of emphysema. J Thorac Imaging. 1986 Mar;1(2):94–103. doi: 10.1097/00005382-198603000-00010. [DOI] [PubMed] [Google Scholar]
  6. Brown M. S., McNitt-Gray M. F., Goldin J. G., Greaser L. E., Hayward U. M., Sayre J. W., Arid M. K., Aberle D. R. Automated measurement of single and total lung volume from CT. J Comput Assist Tomogr. 1999 Jul-Aug;23(4):632–640. doi: 10.1097/00004728-199907000-00027. [DOI] [PubMed] [Google Scholar]
  7. Coxson H. O., Rogers R. M., Whittall K. P., D'yachkova Y., Paré P. D., Sciurba F. C., Hogg J. C. A quantification of the lung surface area in emphysema using computed tomography. Am J Respir Crit Care Med. 1999 Mar;159(3):851–856. doi: 10.1164/ajrccm.159.3.9805067. [DOI] [PubMed] [Google Scholar]
  8. Dirksen A., Friis M., Olesen K. P., Skovgaard L. T., Sørensen K. Progress of emphysema in severe alpha 1-antitrypsin deficiency as assessed by annual CT. Acta Radiol. 1997 Sep;38(5):826–832. doi: 10.1080/02841859709172418. [DOI] [PubMed] [Google Scholar]
  9. Fraser R. G., Fraser R. S., Renner J. W., Bernard C., Fitzgerald P. J. The roentgenologic diagnosis of chronic bronchitis: a reassessment with emphasis on parahilar bronchi seen end-on. Radiology. 1976 Jul;120(1):1–9. doi: 10.1148/120.1.1. [DOI] [PubMed] [Google Scholar]
  10. Gelb A. F., Zamel N., Hogg J. C., Müller N. L., Schein M. J. Pseudophysiologic emphysema resulting from severe small-airways disease. Am J Respir Crit Care Med. 1998 Sep;158(3):815–819. doi: 10.1164/ajrccm.158.3.9801045. [DOI] [PubMed] [Google Scholar]
  11. Gevenois P. A., De Vuyst P., de Maertelaer V., Zanen J., Jacobovitz D., Cosio M. G., Yernault J. C. Comparison of computed density and microscopic morphometry in pulmonary emphysema. Am J Respir Crit Care Med. 1996 Jul;154(1):187–192. doi: 10.1164/ajrccm.154.1.8680679. [DOI] [PubMed] [Google Scholar]
  12. Gevenois P. A., Yernault J. C. Can computed tomography quantify pulmonary emphysema? Eur Respir J. 1995 May;8(5):843–848. [PubMed] [Google Scholar]
  13. Gevenois P. A., de Maertelaer V., De Vuyst P., Zanen J., Yernault J. C. Comparison of computed density and macroscopic morphometry in pulmonary emphysema. Am J Respir Crit Care Med. 1995 Aug;152(2):653–657. doi: 10.1164/ajrccm.152.2.7633722. [DOI] [PubMed] [Google Scholar]
  14. Gould G. A., MacNee W., McLean A., Warren P. M., Redpath A., Best J. J., Lamb D., Flenley D. C. CT measurements of lung density in life can quantitate distal airspace enlargement--an essential defining feature of human emphysema. Am Rev Respir Dis. 1988 Feb;137(2):380–392. doi: 10.1164/ajrccm/137.2.380. [DOI] [PubMed] [Google Scholar]
  15. Guest P. J., Hansell D. M. High resolution computed tomography (HRCT) in emphysema associated with alpha-1-antitrypsin deficiency. Clin Radiol. 1992 Apr;45(4):260–266. doi: 10.1016/s0009-9260(05)80011-x. [DOI] [PubMed] [Google Scholar]
  16. Gurney J. W., Jones K. K., Robbins R. A., Gossman G. L., Nelson K. J., Daughton D., Spurzem J. R., Rennard S. I. Regional distribution of emphysema: correlation of high-resolution CT with pulmonary function tests in unselected smokers. Radiology. 1992 May;183(2):457–463. doi: 10.1148/radiology.183.2.1561350. [DOI] [PubMed] [Google Scholar]
  17. Hayhurst M. D., MacNee W., Flenley D. C., Wright D., McLean A., Lamb D., Wightman A. J., Best J. Diagnosis of pulmonary emphysema by computerised tomography. Lancet. 1984 Aug 11;2(8398):320–322. doi: 10.1016/s0140-6736(84)92689-8. [DOI] [PubMed] [Google Scholar]
  18. Hruban R. H., Meziane M. A., Zerhouni E. A., Khouri N. F., Fishman E. K., Wheeler P. S., Dumler J. S., Hutchins G. M. High resolution computed tomography of inflation-fixed lungs. Pathologic-radiologic correlation of centrilobular emphysema. Am Rev Respir Dis. 1987 Oct;136(4):935–940. doi: 10.1164/ajrccm/136.4.935. [DOI] [PubMed] [Google Scholar]
  19. Kauczor H. U., Heussel C. P., Fischer B., Klamm R., Mildenberger P., Thelen M. Assessment of lung volumes using helical CT at inspiration and expiration: comparison with pulmonary function tests. AJR Am J Roentgenol. 1998 Oct;171(4):1091–1095. doi: 10.2214/ajr.171.4.9763003. [DOI] [PubMed] [Google Scholar]
  20. King G. G., Müller N. L., Whittall K. P., Xiang Q. S., Paré P. D. An analysis algorithm for measuring airway lumen and wall areas from high-resolution computed tomographic data. Am J Respir Crit Care Med. 2000 Feb;161(2 Pt 1):574–580. doi: 10.1164/ajrccm.161.2.9812073. [DOI] [PubMed] [Google Scholar]
  21. Klein J. S., Gamsu G., Webb W. R., Golden J. A., Müller N. L. High-resolution CT diagnosis of emphysema in symptomatic patients with normal chest radiographs and isolated low diffusing capacity. Radiology. 1992 Mar;182(3):817–821. doi: 10.1148/radiology.182.3.1535900. [DOI] [PubMed] [Google Scholar]
  22. Kuwano K., Matsuba K., Ikeda T., Murakami J., Araki A., Nishitani H., Ishida T., Yasumoto K., Shigematsu N. The diagnosis of mild emphysema. Correlation of computed tomography and pathology scores. Am Rev Respir Dis. 1990 Jan;141(1):169–178. doi: 10.1164/ajrccm/141.1.169. [DOI] [PubMed] [Google Scholar]
  23. Lamers R. J., Thelissen G. R., Kessels A. G., Wouters E. F., van Engelshoven J. M. Chronic obstructive pulmonary disease: evaluation with spirometrically controlled CT lung densitometry. Radiology. 1994 Oct;193(1):109–113. doi: 10.1148/radiology.193.1.8090878. [DOI] [PubMed] [Google Scholar]
  24. McNamara A. E., Müller N. L., Okazawa M., Arntorp J., Wiggs B. R., Paré P. D. Airway narrowing in excised canine lungs measured by high-resolution computed tomography. J Appl Physiol (1985) 1992 Jul;73(1):307–316. doi: 10.1152/jappl.1992.73.1.307. [DOI] [PubMed] [Google Scholar]
  25. McNitt-Gray M. F., Goldin J. G., Johnson T. D., Tashkin D. P., Aberle D. R. Development and testing of image-processing methods for the quantitative assessment of airway hyperresponsiveness from high-resolution CT images. J Comput Assist Tomogr. 1997 Nov-Dec;21(6):939–947. doi: 10.1097/00004728-199711000-00017. [DOI] [PubMed] [Google Scholar]
  26. Mergo P. J., Williams W. F., Gonzalez-Rothi R., Gibson R., Ros P. R., Staab E. V., Helmberger T. Three-dimensional volumetric assessment of abnormally low attenuation of the lung from routine helical CT: inspiratory and expiratory quantification. AJR Am J Roentgenol. 1998 May;170(5):1355–1360. doi: 10.2214/ajr.170.5.9574615. [DOI] [PubMed] [Google Scholar]
  27. Miller R. R., Müller N. L., Vedal S., Morrison N. J., Staples C. A. Limitations of computed tomography in the assessment of emphysema. Am Rev Respir Dis. 1989 Apr;139(4):980–983. doi: 10.1164/ajrccm/139.4.980. [DOI] [PubMed] [Google Scholar]
  28. Murata K., Itoh H., Todo G., Kanaoka M., Noma S., Itoh T., Furuta M., Asamoto H., Torizuka K. Centrilobular lesions of the lung: demonstration by high-resolution CT and pathologic correlation. Radiology. 1986 Dec;161(3):641–645. doi: 10.1148/radiology.161.3.3786710. [DOI] [PubMed] [Google Scholar]
  29. Murata K., Khan A., Herman P. G. Pulmonary parenchymal disease: evaluation with high-resolution CT. Radiology. 1989 Mar;170(3 Pt 1):629–635. doi: 10.1148/radiology.170.3.2916013. [DOI] [PubMed] [Google Scholar]
  30. Müller N. L., Staples C. A., Miller R. R., Abboud R. T. "Density mask". An objective method to quantitate emphysema using computed tomography. Chest. 1988 Oct;94(4):782–787. doi: 10.1378/chest.94.4.782. [DOI] [PubMed] [Google Scholar]
  31. Nakano Y., Muro S., Sakai H., Hirai T., Chin K., Tsukino M., Nishimura K., Itoh H., Paré P. D., Hogg J. C. Computed tomographic measurements of airway dimensions and emphysema in smokers. Correlation with lung function. Am J Respir Crit Care Med. 2000 Sep;162(3 Pt 1):1102–1108. doi: 10.1164/ajrccm.162.3.9907120. [DOI] [PubMed] [Google Scholar]
  32. Nicklaus T. M., Stowell D. W., Christiansen W. R., Renzetti A. D., Jr The accuracy of the roentgenologic diagnosis of chronic pulmonary emphysema. Am Rev Respir Dis. 1966 Jun;93(6):889–899. doi: 10.1164/arrd.1966.93.6.889. [DOI] [PubMed] [Google Scholar]
  33. Okazawa M., Müller N., McNamara A. E., Child S., Verburgt L., Paré P. D. Human airway narrowing measured using high resolution computed tomography. Am J Respir Crit Care Med. 1996 Nov;154(5):1557–1562. doi: 10.1164/ajrccm.154.5.8912780. [DOI] [PubMed] [Google Scholar]
  34. Park K. J., Bergin C. J., Clausen J. L. Quantitation of emphysema with three-dimensional CT densitometry: comparison with two-dimensional analysis, visual emphysema scores, and pulmonary function test results. Radiology. 1999 May;211(2):541–547. doi: 10.1148/radiology.211.2.r99ma52541. [DOI] [PubMed] [Google Scholar]
  35. Pratt P. C. Role of conventional chest radiography in diagnosis and exclusion of emphysema. Am J Med. 1987 May;82(5):998–1006. doi: 10.1016/0002-9343(87)90163-x. [DOI] [PubMed] [Google Scholar]
  36. Reinhardt J. M., D'Souza N. D., Hoffman E. A. Accurate measurement of intrathoracic airways. IEEE Trans Med Imaging. 1997 Dec;16(6):820–827. doi: 10.1109/42.650878. [DOI] [PubMed] [Google Scholar]
  37. Remy-Jardin M., Remy J., Gosselin B., Becette V., Edme J. L. Lung parenchymal changes secondary to cigarette smoking: pathologic-CT correlations. Radiology. 1993 Mar;186(3):643–651. doi: 10.1148/radiology.186.3.8430168. [DOI] [PubMed] [Google Scholar]
  38. Remy-Jardin M., Remy J., Gosselin B., Copin M. C., Wurtz A., Duhamel A. Sliding thin slab, minimum intensity projection technique in the diagnosis of emphysema: histopathologic-CT correlation. Radiology. 1996 Sep;200(3):665–671. doi: 10.1148/radiology.200.3.8756912. [DOI] [PubMed] [Google Scholar]
  39. SIMON G., GALBRAITH H. J. Radiology of chronic bronchitis. Lancet. 1953 Oct 24;265(6791):850–852. doi: 10.1016/s0140-6736(53)90519-4. [DOI] [PubMed] [Google Scholar]
  40. SUTINEN S., CHRISTOFORIDIS A. J., KLUGH G. A., PRATT P. C. ROENTGENOLOGIC CRITERIA FOR THE RECOGNITION OF NONSYMPTOMATIC PULMONARY EMPHYSEMA. CORRELATION BETWEEN ROENTGENOLOGIC FINDINGS AND PULMONARY PATHOLOGY. Am Rev Respir Dis. 1965 Jan;91:69–76. doi: 10.1164/arrd.1965.91.1.69. [DOI] [PubMed] [Google Scholar]
  41. Senéterre E., Paganin F., Bruel J. M., Michel F. B., Bousquet J. Measurement of the internal size of bronchi using high resolution computed tomography (HRCT) Eur Respir J. 1994 Mar;7(3):596–600. doi: 10.1183/09031936.94.07030596. [DOI] [PubMed] [Google Scholar]
  42. Spouge D., Mayo J. R., Cardoso W., Müller N. L. Panacinar emphysema: CT and pathologic findings. J Comput Assist Tomogr. 1993 Sep-Oct;17(5):710–713. [PubMed] [Google Scholar]
  43. Thurlbeck W. M., Müller N. L. Emphysema: definition, imaging, and quantification. AJR Am J Roentgenol. 1994 Nov;163(5):1017–1025. doi: 10.2214/ajr.163.5.7976869. [DOI] [PubMed] [Google Scholar]
  44. Thurlbeck W. M., Simon G. Radiographic appearance of the chest in emphysema. AJR Am J Roentgenol. 1978 Mar;130(3):429–440. doi: 10.2214/ajr.130.3.429. [DOI] [PubMed] [Google Scholar]
  45. Uppaluri R., Mitsa T., Sonka M., Hoffman E. A., McLennan G. Quantification of pulmonary emphysema from lung computed tomography images. Am J Respir Crit Care Med. 1997 Jul;156(1):248–254. doi: 10.1164/ajrccm.156.1.9606093. [DOI] [PubMed] [Google Scholar]
  46. Webb W. R., Gamsu G., Wall S. D., Cann C. E., Proctor E. CT of a bronchial phantom. Factors affecting appearance and size measurements. Invest Radiol. 1984 Sep-Oct;19(5):394–398. doi: 10.1097/00004424-198409000-00011. [DOI] [PubMed] [Google Scholar]
  47. Webb W. R. Radiology of obstructive pulmonary disease. AJR Am J Roentgenol. 1997 Sep;169(3):637–647. doi: 10.2214/ajr.169.3.9275869. [DOI] [PubMed] [Google Scholar]
  48. Webb W. R., Stein M. G., Finkbeiner W. E., Im J. G., Lynch D., Gamsu G. Normal and diseased isolated lungs: high-resolution CT. Radiology. 1988 Jan;166(1 Pt 1):81–87. doi: 10.1148/radiology.166.1.3336706. [DOI] [PubMed] [Google Scholar]
  49. Zagers H., Vrooman H. A., Aarts N. J., Stolk J., Schultze Kool L. J., Dijkman J. H., Van Voorthuisen A. E., Reiber J. H. Assessment of the progression of emphysema by quantitative analysis of spirometrically gated computed tomography images. Invest Radiol. 1996 Dec;31(12):761–767. doi: 10.1097/00004424-199612000-00005. [DOI] [PubMed] [Google Scholar]

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