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- Archer S. L., Weir E. K., Reeve H. L., Michelakis E. Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation. Adv Exp Med Biol. 2000;475:219–240. doi: 10.1007/0-306-46825-5_21. [DOI] [PubMed] [Google Scholar]
- Archie J. P., Jr Mathematic coupling of data: a common source of error. Ann Surg. 1981 Mar;193(3):296–303. doi: 10.1097/00000658-198103000-00008. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bernard G. R., Vincent J. L., Laterre P. F., LaRosa S. P., Dhainaut J. F., Lopez-Rodriguez A., Steingrub J. S., Garber G. E., Helterbrand J. D., Ely E. W. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001 Mar 8;344(10):699–709. doi: 10.1056/NEJM200103083441001. [DOI] [PubMed] [Google Scholar]
- Bihari D., Smithies M., Gimson A., Tinker J. The effects of vasodilation with prostacyclin on oxygen delivery and uptake in critically ill patients. N Engl J Med. 1987 Aug 13;317(7):397–403. doi: 10.1056/NEJM198708133170701. [DOI] [PubMed] [Google Scholar]
- Boyd O., Grounds R. M., Bennett E. D. A randomized clinical trial of the effect of deliberate perioperative increase of oxygen delivery on mortality in high-risk surgical patients. JAMA. 1993 Dec 8;270(22):2699–2707. [PubMed] [Google Scholar]
- Bradley S. G. Cellular and molecular mechanisms of action of bacterial endotoxins. Annu Rev Microbiol. 1979;33:67–94. doi: 10.1146/annurev.mi.33.100179.000435. [DOI] [PubMed] [Google Scholar]
- Cain S. M., Curtis S. E. Experimental models of pathologic oxygen supply dependency. Crit Care Med. 1991 May;19(5):603–612. doi: 10.1097/00003246-199105000-00006. [DOI] [PubMed] [Google Scholar]
- Cartee G. D., Douen A. G., Ramlal T., Klip A., Holloszy J. O. Stimulation of glucose transport in skeletal muscle by hypoxia. J Appl Physiol (1985) 1991 Apr;70(4):1593–1600. doi: 10.1152/jappl.1991.70.4.1593. [DOI] [PubMed] [Google Scholar]
- Clerbaux T., Detry B., Reynaert M., Kreuzer F., Frans A. Reestimation of the effects of inorganic phosphates on the equilibrium between oxygen and hemoglobin. Intensive Care Med. 1992;18(4):222–225. doi: 10.1007/BF01709836. [DOI] [PubMed] [Google Scholar]
- Connors A. F., Jr, Speroff T., Dawson N. V., Thomas C., Harrell F. E., Jr, Wagner D., Desbiens N., Goldman L., Wu A. W., Califf R. M. The effectiveness of right heart catheterization in the initial care of critically ill patients. SUPPORT Investigators. JAMA. 1996 Sep 18;276(11):889–897. doi: 10.1001/jama.276.11.889. [DOI] [PubMed] [Google Scholar]
- Curtis S. E., Cain S. M. Regional and systemic oxygen delivery/uptake relations and lactate flux in hyperdynamic, endotoxin-treated dogs. Am Rev Respir Dis. 1992 Feb;145(2 Pt 1):348–354. doi: 10.1164/ajrccm/145.2_Pt_1.348. [DOI] [PubMed] [Google Scholar]
- Fellows I. W., Bennett T., MacDonald I. A. The effect of adrenaline upon cardiovascular and metabolic functions in man. Clin Sci (Lond) 1985 Aug;69(2):215–222. doi: 10.1042/cs0690215. [DOI] [PubMed] [Google Scholar]
- Gattinoni L., Brazzi L., Pelosi P., Latini R., Tognoni G., Pesenti A., Fumagalli R. A trial of goal-oriented hemodynamic therapy in critically ill patients. SvO2 Collaborative Group. N Engl J Med. 1995 Oct 19;333(16):1025–1032. doi: 10.1056/NEJM199510193331601. [DOI] [PubMed] [Google Scholar]
- Gutierrez G., Palizas F., Doglio G., Wainsztein N., Gallesio A., Pacin J., Dubin A., Schiavi E., Jorge M., Pusajo J. Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients. Lancet. 1992 Jan 25;339(8787):195–199. doi: 10.1016/0140-6736(92)90002-k. [DOI] [PubMed] [Google Scholar]
- Harrison M. J., Pollock S., Kendall B. E., Marshall J. Effect of haematocrit on carotid stenosis and cerebral infarction. Lancet. 1981 Jul 18;2(8238):114–115. doi: 10.1016/s0140-6736(81)90298-1. [DOI] [PubMed] [Google Scholar]
- Hochachka P. W., Buck L. T., Doll C. J., Land S. C. Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack. Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9493–9498. doi: 10.1073/pnas.93.18.9493. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hébert P. C., Wells G., Blajchman M. A., Marshall J., Martin C., Pagliarello G., Tweeddale M., Schweitzer I., Yetisir E. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med. 1999 Feb 11;340(6):409–417. doi: 10.1056/NEJM199902113400601. [DOI] [PubMed] [Google Scholar]
- Karimova A., Pinsky D. J. The endothelial response to oxygen deprivation: biology and clinical implications. Intensive Care Med. 2001 Jan;27(1):19–31. doi: 10.1007/s001340000790. [DOI] [PubMed] [Google Scholar]
- Leach R. M., Hill H. M., Snetkov V. A., Robertson T. P., Ward J. P. Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor. J Physiol. 2001 Oct 1;536(Pt 1):211–224. doi: 10.1111/j.1469-7793.2001.00211.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Leach R. M., Treacher D. F. The relationship between oxygen delivery and consumption. Dis Mon. 1994 Jul;40(7):301–368. [PubMed] [Google Scholar]
- Lobo S. M., Salgado P. F., Castillo V. G., Borim A. A., Polachini C. A., Palchetti J. C., Brienzi S. L., de Oliveira G. G. Effects of maximizing oxygen delivery on morbidity and mortality in high-risk surgical patients. Crit Care Med. 2000 Oct;28(10):3396–3404. doi: 10.1097/00003246-200010000-00003. [DOI] [PubMed] [Google Scholar]
- Mohsenifar Z., Amin D., Jasper A. C., Shah P. K., Koerner S. K. Dependence of oxygen consumption on oxygen delivery in patients with chronic congestive heart failure. Chest. 1987 Sep;92(3):447–450. doi: 10.1378/chest.92.3.447. [DOI] [PubMed] [Google Scholar]
- Nelson D. P., Samsel R. W., Wood L. D., Schumacker P. T. Pathological supply dependence of systemic and intestinal O2 uptake during endotoxemia. J Appl Physiol (1985) 1988 Jun;64(6):2410–2419. doi: 10.1152/jappl.1988.64.6.2410. [DOI] [PubMed] [Google Scholar]
- Paul R. J. Smooth muscle energetics. Annu Rev Physiol. 1989;51:331–349. doi: 10.1146/annurev.ph.51.030189.001555. [DOI] [PubMed] [Google Scholar]
- Petros A., Bennett D., Vallance P. Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock. Lancet. 1991 Dec 21;338(8782-8783):1557–1558. doi: 10.1016/0140-6736(91)92376-d. [DOI] [PubMed] [Google Scholar]
- Robin E. D. Of men and mitochondria: coping with hypoxic dysoxia. The 1980 J. Burns Amberson Lecture. Am Rev Respir Dis. 1980 Oct;122(4):517–531. doi: 10.1164/arrd.1980.122.4.517. [DOI] [PubMed] [Google Scholar]
- Schumacker P. T., Cain S. M. The concept of a critical oxygen delivery. Intensive Care Med. 1987;13(4):223–229. doi: 10.1007/BF00265110. [DOI] [PubMed] [Google Scholar]
- Schumacker P. T., Samsel R. W. Analysis of oxygen delivery and uptake relationships in the Krogh tissue model. J Appl Physiol (1985) 1989 Sep;67(3):1234–1244. doi: 10.1152/jappl.1989.67.3.1234. [DOI] [PubMed] [Google Scholar]
- Semenza G. L. Hypoxia-inducible factor 1: master regulator of O2 homeostasis. Curr Opin Genet Dev. 1998 Oct;8(5):588–594. doi: 10.1016/s0959-437x(98)80016-6. [DOI] [PubMed] [Google Scholar]
- Shoemaker W. C., Appel P. L., Kram H. B., Waxman K., Lee T. S. Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients. Chest. 1988 Dec;94(6):1176–1186. doi: 10.1378/chest.94.6.1176. [DOI] [PubMed] [Google Scholar]
- Shoemaker W. C., Appel P. L., Waxman K., Schwartz S., Chang P. Clinical trial of survivors' cardiorespiratory patterns as therapeutic goals in critically ill postoperative patients. Crit Care Med. 1982 Jun;10(6):398–403. doi: 10.1097/00003246-198206000-00015. [DOI] [PubMed] [Google Scholar]
- Silverman H. J. Lack of a relationship between induced changes in oxygen consumption and changes in lactate levels. Chest. 1991 Oct;100(4):1012–1015. doi: 10.1378/chest.100.4.1012. [DOI] [PubMed] [Google Scholar]
- Sinclair S., James S., Singer M. Intraoperative intravascular volume optimisation and length of hospital stay after repair of proximal femoral fracture: randomised controlled trial. BMJ. 1997 Oct 11;315(7113):909–912. doi: 10.1136/bmj.315.7113.909. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stephan H., Sonntag H., Henning H., Yoshimine K. Cardiovascular and renal haemodynamic effects of dopexamine: comparison with dopamine. Br J Anaesth. 1990 Sep;65(3):380–387. doi: 10.1093/bja/65.3.380. [DOI] [PubMed] [Google Scholar]
- Vary T. C., Siegel J. H., Nakatani T., Sato T., Aoyama H. Effect of sepsis on activity of pyruvate dehydrogenase complex in skeletal muscle and liver. Am J Physiol. 1986 Jun;250(6 Pt 1):E634–E640. doi: 10.1152/ajpendo.1986.250.6.E634. [DOI] [PubMed] [Google Scholar]
- Vincent J. L., Roman A., De Backer D., Kahn R. J. Oxygen uptake/supply dependency. Effects of short-term dobutamine infusion. Am Rev Respir Dis. 1990 Jul;142(1):2–7. doi: 10.1164/ajrccm/142.6_Pt_2.S2. [DOI] [PubMed] [Google Scholar]
- Wilson D. F., Erecińska M., Drown C., Silver I. A. Effect of oxygen tension on cellular energetics. Am J Physiol. 1977 Nov;233(5):C135–C140. doi: 10.1152/ajpcell.1977.233.5.C135. [DOI] [PubMed] [Google Scholar]
- Wilson J., Woods I., Fawcett J., Whall R., Dibb W., Morris C., McManus E. Reducing the risk of major elective surgery: randomised controlled trial of preoperative optimisation of oxygen delivery. BMJ. 1999 Apr 24;318(7191):1099–1103. doi: 10.1136/bmj.318.7191.1099. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yan S. F., Lu J., Zou Y. S., Soh-Won J., Cohen D. M., Buttrick P. M., Cooper D. R., Steinberg S. F., Mackman N., Pinsky D. J. Hypoxia-associated induction of early growth response-1 gene expression. J Biol Chem. 1999 May 21;274(21):15030–15040. doi: 10.1074/jbc.274.21.15030. [DOI] [PubMed] [Google Scholar]