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. 2003 Jun;58(6):515–518. doi: 10.1136/thorax.58.6.515

Health status measurement: sensitivity of the self-reported Chronic Respiratory Questionnaire (CRQ-SR) in pulmonary rehabilitation

J Williams 1, S Singh 1, L Sewell 1, M Morgan 1
PMCID: PMC1746719  PMID: 12775865

Abstract

Background: A self-reported CRQ (CRQ-SR) has recently been developed and found to be a reproducible and reliable measure of health status. This study explores both the sensitivity of the CRQ-SR and relative sensitivity compared with the conventional interviewer led CRQ (CRQ-IL) in patients undergoing pulmonary rehabilitation.

Methods: Eighty patients with stable chronic obstructive pulmonary disease who had been referred for pulmonary rehabilitation completed the CRQ-SR at initial assessment and at the end of the 7 week programme. A further 35 patients completed both the CRQ-SR and the CRQ-IL, administered 1 week apart, before starting rehabilitation and again at the end of the programme.

Results: There were large statistically and clinically significant changes in mean score per dimension following rehabilitation in all dimensions of the CRQ-SR (dyspnoea mean difference 0.87 (95% CI 0.61 to 1.14); fatigue 0.76 (0.53 to 1.0); emotion 0.60 (0.35 to 0.86); mastery 0.76 (0.52 to 1.0); p<0.001). Similar results were found in the comparison of the sensitivity of the CRQ-SR and the CRQ-IL, with large changes in mean score per dimension following rehabilitation for both versions of the questionnaire (p<0.005). No significant differences were seen in the magnitude of change between the two formats of the questionnaire (p>0.05).

Conclusion: The self-reported CRQ is as sensitive to change as the interviewer led CRQ in patients undergoing pulmonary rehabilitation but has the advantage of being less time consuming to administer.

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Selected References

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  1. Bland J. M., Altman D. G. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986 Feb 8;1(8476):307–310. [PubMed] [Google Scholar]
  2. Cook D. J., Guyatt G. H., Juniper E., Griffith L., McIlroy W., Willan A., Jaeschke R., Epstein R. Interviewer versus self-administered questionnaires in developing a disease-specific, health-related quality of life instrument for asthma. J Clin Epidemiol. 1993 Jun;46(6):529–534. doi: 10.1016/0895-4356(93)90125-k. [DOI] [PubMed] [Google Scholar]
  3. Griffiths T. L., Burr M. L., Campbell I. A., Lewis-Jenkins V., Mullins J., Shiels K., Turner-Lawlor P. J., Payne N., Newcombe R. G., Ionescu A. A. Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial. Lancet. 2000 Jan 29;355(9201):362–368. doi: 10.1016/s0140-6736(99)07042-7. [DOI] [PubMed] [Google Scholar]
  4. Guyatt G. H., Berman L. B., Townsend M., Pugsley S. O., Chambers L. W. A measure of quality of life for clinical trials in chronic lung disease. Thorax. 1987 Oct;42(10):773–778. doi: 10.1136/thx.42.10.773. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Guyatt G. H., King D. R., Feeny D. H., Stubbing D., Goldstein R. S. Generic and specific measurement of health-related quality of life in a clinical trial of respiratory rehabilitation. J Clin Epidemiol. 1999 Mar;52(3):187–192. doi: 10.1016/s0895-4356(98)00157-7. [DOI] [PubMed] [Google Scholar]
  6. Guyatt G. H., Townsend M., Keller J., Singer J., Nogradi S. Measuring functional status in chronic lung disease: conclusions from a randomized control trial. Respir Med. 1989 Jul;83(4):293–297. doi: 10.1016/s0954-6111(89)80199-4. [DOI] [PubMed] [Google Scholar]
  7. Güell R., Casan P., Belda J., Sangenis M., Morante F., Guyatt G. H., Sanchis J. Long-term effects of outpatient rehabilitation of COPD: A randomized trial. Chest. 2000 Apr;117(4):976–983. doi: 10.1378/chest.117.4.976. [DOI] [PubMed] [Google Scholar]
  8. Harper R., Brazier J. E., Waterhouse J. C., Walters S. J., Jones N. M., Howard P. Comparison of outcome measures for patients with chronic obstructive pulmonary disease (COPD) in an outpatient setting. Thorax. 1997 Oct;52(10):879–887. doi: 10.1136/thx.52.10.879. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Jones P. W. Health status measurement in chronic obstructive pulmonary disease. Thorax. 2001 Nov;56(11):880–887. doi: 10.1136/thorax.56.11.880. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Lacasse Y., Wong E., Guyatt G. H., King D., Cook D. J., Goldstein R. S. Meta-analysis of respiratory rehabilitation in chronic obstructive pulmonary disease. Lancet. 1996 Oct 26;348(9035):1115–1119. doi: 10.1016/S0140-6736(96)04201-8. [DOI] [PubMed] [Google Scholar]
  11. Redelmeier D. A., Guyatt G. H., Goldstein R. S. Assessing the minimal important difference in symptoms: a comparison of two techniques. J Clin Epidemiol. 1996 Nov;49(11):1215–1219. doi: 10.1016/s0895-4356(96)00206-5. [DOI] [PubMed] [Google Scholar]
  12. Singh S. J., Morgan M. D., Scott S., Walters D., Hardman A. E. Development of a shuttle walking test of disability in patients with chronic airways obstruction. Thorax. 1992 Dec;47(12):1019–1024. doi: 10.1136/thx.47.12.1019. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Singh S. J., Smith D. L., Hyland M. E., Morgan M. D. A short outpatient pulmonary rehabilitation programme: immediate and longer-term effects on exercise performance and quality of life. Respir Med. 1998 Sep;92(9):1146–1154. doi: 10.1016/s0954-6111(98)90410-3. [DOI] [PubMed] [Google Scholar]
  14. Wijkstra P. J., TenVergert E. M., Van Altena R., Otten V., Postma D. S., Kraan J., Koëter G. H. Reliability and validity of the chronic respiratory questionnaire (CRQ). Thorax. 1994 May;49(5):465–467. doi: 10.1136/thx.49.5.465. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Williams J. E., Singh S. J., Sewell L., Guyatt G. H., Morgan M. D. Development of a self-reported Chronic Respiratory Questionnaire (CRQ-SR). Thorax. 2001 Dec;56(12):954–959. doi: 10.1136/thorax.56.12.954. [DOI] [PMC free article] [PubMed] [Google Scholar]

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