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. 1987 Feb;31(2):168–172. doi: 10.1128/aac.31.2.168

Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon.

K L Hartshorn, M W Vogt, T C Chou, R S Blumberg, R Byington, R T Schooley, M S Hirsch
PMCID: PMC174685  PMID: 3471180

Abstract

Both recombinant alpha A interferon and azidothymidine inhibit the replication of human immunodeficiency virus in peripheral blood mononuclear cells. Combinations of recombinant alpha A interferon and azidothymidine at concentrations that are easily achievable in patients synergistically inhibit human immunodeficiency virus in vitro with minimal toxicity. Combinations of antiretroviral compounds that act by different mechanisms may prove useful in the treatment of acquired immunodeficiency syndrome-related disorders.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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