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. 2005 Oct;60(10):880–881. doi: 10.1136/thx.2004.027508

CPAP suppression of awake right-to-left shunting through patent foramen ovale in a patient with obstructive sleep apnoea

C Pinet 1, J Orehek 1
PMCID: PMC1747216  PMID: 16192368

Abstract

The prevalence of an echocardiographically visible patent foramen ovale (PFO) is higher in patients with obstructive sleep apnoea syndrome (OSAS) than in normal controls. We report a patient who presented with OSAS and right-to-left shunting (RLS) through the PFO in whom the RLS disappeared after treatment for 1 week with nocturnal continuous positive airway pressure (CPAP). This case shows the role of OSA in generating an awake RLS through a PFO and its possible reversibility by CPAP. The mechanism of reversible awake RLS through PFO in OSAS is discussed.

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