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. 1987 Apr;31(4):535–538. doi: 10.1128/aac.31.4.535

Comparative double-blind study of 200- and 400-mg enoxacin given orally in the treatment of acute uncomplicated urethral gonorrhea in males.

A H van der Willigen, J C van der Hoek, J H Wagenvoort, H J van Vliet, B van Klingeren, W O Schalla, J S Knapp, T van Joost, M F Michel, E Stolz
PMCID: PMC174773  PMID: 3111354

Abstract

In a double-blind randomized study, 155 male patients with uncomplicated urethral gonorrhea were given 200 mg (one capsule with 200 mg and one capsule with placebo; n = 77) or 400 mg (two capsules with 200 mg; n = 78) of enoxacin orally. The cure rates in the 200- and 400-mg treatment groups were 90 and 92%, respectively. The enoxacin MIC for the isolated Neisseria gonorrhoeae strains ranged from 0.015 to 0.12 microgram/ml. Postgonococcal urethritis was diagnosed in 29 (42%) patients in the 200-mg treatment group and 19 (26%) patients in the 400-mg treatment group. Side effects (nausea, headache, and vomiting) occurred in 2 (3%) of the 77 patients in the 200-mg treatment group and in 3 (4%) of the 78 patients in the 400-mg treatment group.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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