Correction for Bielas et al., Human cancers express a mutator phenotype

MEDICAL SCIENCES. For the article “Human cancers express a mutator phenotype,” by Jason H. Bielas Keith R. Loeb Brian P. Rubin Lawrence D. True and Lawrence A. Loeb, which appeared in issue 48, November 28, 2006, of Proc Natl Acad Sci USA (103:18238–18242; first published November 15, 2006; 10.1073/pnas.0607057103), several references to nucleotide instability (NIN) should have appeared as point mutation instability (PIN). On page 18238, in the key terms, “nucleotide instability (NIN)” should be replaced with “point mutation instability (PIN).” On page 18239, in the last sentence of the first paragraph of the Discussion, “nucleotide instability or NIN” should read: “point mutation instability or PIN.” Last, on page 18239, in the last sentence of the second paragraph of the Discussion, “an increase in NIN” should read: “an increase in PIN.” The online version has been corrected. These errors do not affect the conclusions of the article.