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Bulletin of the New York Academy of Medicine logoLink to Bulletin of the New York Academy of Medicine
. 1971 Mar;47(3):303–322.

Disturbance of function (functio laesa): the legendary fifth cardinal sign of inflammation, added by Galen to the four cardinal signs of Celsus.

L J Rather
PMCID: PMC1749862  PMID: 5276838

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