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. 1997 May;65(5):1956–1959. doi: 10.1128/iai.65.5.1956-1959.1997

Temporal production of streptococcal erythrogenic toxin B (streptococcal cysteine proteinase) in response to nutrient depletion.

M S Chaussee 1, E R Phillips 1, J J Ferretti 1
PMCID: PMC175251  PMID: 9125588

Abstract

The effects of various growth conditions on the production of streptococcal erythrogenic toxin B (streptococcal pyrogenic exotoxin B [SPE B]) by Streptococcus pyogenes were analyzed. SPE B was detected in broth culture supernatant fluid only during the stationary phase of growth when glucose and other potential carbon sources were depleted from the medium. Additionally, SPE B production was inhibited when the concentration of glucose in the medium was maintained. These results suggest that SPE B is secreted under conditions of starvation and may be involved in nutrient acquisition.

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Selected References

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