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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 2001 Jan;60(1):83–86. doi: 10.1136/ard.60.1.83

HHV8 associated Kaposi's sarcoma during triple immunosuppressive treatment with cyclosporin A, azathioprine, and prednisolone for ocular Behçet's disease and complete remission of both disorders with interferon α

I Kotter 1, C Aepinus 1, F Graepler 1, V Gartner 1, A Eckstein 1, N Stubiger 1, B Kaskas 1, M Zierhut 1, B Bultmann 1, R Kandolf 1, L Kanz 1
PMCID: PMC1753365  PMID: 11114291

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Figure 1  .

Figure 1  

(A) Tumour at the hard palate of the patient (reddish lesion). (B) Chest x ray in February 1994, showing multiple nodular infiltrates and lymphangiosis. (C) Chest x ray in May 1994, showing resolution of the nodular infiltrates and lymphangiosis.

Figure 2  .

Figure 2  

(A) Histology of the lesion from the hard palate, showing features of Kaposi's sarcoma with spindle shaped cells. (B) Histology of the caecum showing unspecific colitis.

Figure 3  .

Figure 3  

Polymerase chain reaction (PCR) amplificates are shown by ultraviolet illumination of an ethidium bromide stained 2% agarose gel. Lanes 1-4 show the HCMV-IE gene-specific PCR amplicons obtained with 200 ng DNA extracted from the caecum (lane 1), hard palate (lane 2), negative and positive controls (lanes 3 and 4). Lanes 5-8 represent the HHV8-specific amplicons according to Lin et al.7 The sequence of materials is the same as in lanes 1-4. Lanes 9-12 represent the respective K1 (HHV8-K1)-specific amplicons. M is a PhiX Hae III digested DNA marker. The numbers at the left indicate the respective length of the restriction fragments in base pairs.


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