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. 1997 Jun;65(6):2451–2453. doi: 10.1128/iai.65.6.2451-2453.1997

Avirulence of LT2 strains of Salmonella typhimurium results from a defective rpoS gene.

W E Swords 1, B M Cannon 1, W H Benjamin Jr 1
PMCID: PMC175341  PMID: 9169789

Abstract

In order to identify the genetic basis for the attenuation of Salmonella typhimurium LT2 strains, experiments were performed to identify a gene(s) which restores virulence to an avirulent LT2 strain. These and further experiments confirmed that an rpoS mutation is the sole determinant of the attenuation of S. typhimurium LT2.

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Selected References

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