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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 2002 Jan;61(1):59–61. doi: 10.1136/ard.61.1.59

Intravenous immunoglobulins control scleromyxoedema

A Righi 1, F Schiavon 1, S Jablonska 1, A Doria 1, M Blasczyk 1, R Rondinone 1, S Todesco 1, M Cerinic 1
PMCID: PMC1753886  PMID: 11779761

Abstract

Patients: The successful treatment of three cases of scleromyxoedema with IVIg is reported here.

Conclusions: The relatively low risk of the drug and the high effectiveness seen in three patients suggest that IVIg is a new treatment potentially useful in scleromyxoedema.

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Figure 1 .

Figure 1

Patient 1 before the IVIg treatment (November 1998) showing characteristic skin lesion of scleromyxoedema. Papules can be seen on the ears and the forehead, and the face skin is thickened and hardened, reducing the ability to open the eyes and the mouth. Reproduced with permission of the patient.

Figure 2 .

Figure 2

Patient 1 after one month of IVIg treatment (March 1999). The characteristic skin lesions have disappeared. The skin of the face is softer and fewer papules are visible on the forehead. Reproduced with permission of the patient.


Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

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