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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
letter
. 2002 Nov;61(11):1032–1033. doi: 10.1136/ard.61.11.1032

Biochemical and morphological study of human articular chondrocytes cultivated in the presence of pulsed signal therapy

A Fioravanti 1, F Nerucci 1, G Collodel 1, R Markoll 1, R Marcolongo 1
PMCID: PMC1753927  PMID: 12379533

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Figure 1 .

Figure 1

Transmission electron micrographs of chondrocytes cultured in vitro for 72 hours. (A) Basal conditions: the nucleus (N) appears euchromatic, the cytoplasm contains abundant rough endoplasmic reticulum (RER) and lipid droplets (arrows). x9000. (B) IL1ß present: the cell shows a vacuolate cytoplasm devoid of the typical structure. N, nucleus; V, vacuole. x9000. (C) Basal conditions and given PST stimulation: the cell shows an euchromatic nucleus (N) and a cytoplasm rich in rough endoplasmic reticulum (RER) and lipid droplets (arrows). x10 000. (D) IL1ß present and given PST stimulation: the cell clearly recovers its good state of health. Rough endoplasmic reticulum (RER) is present and vacuoles are almost absent. N, nucleus. x9000.


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