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Figure 1 .
Examples of the antigen-specific response to the human (h)-HSP60 or yersinia (Y)-19 kDa compared with stimulation without antigen, in a patient with ankylosing spondylitis (AS) or rheumatoid arthritis (RA) or a healthy control (HC). After staining for T cell surface markers and intracellular cytokines a gate for CD4+ T cells was set. The percentage of IFNγ/CD69 double positive cells of the CD4+ T cell subpopulation is indicated.
Figure 2 .
Percentage of patients with ankylosing spondylitis (AS, n=45), with rheumatoid arthritis (RA, n=22), and of healthy controls (HC, n=20) responding to in vitro stimulation with the human heat shock protein 60 (h-HSP60) or yersinia 19 kDa (Y-19 kDa). Response was measured either by IFNγ or TNFα production of CD4+ T cells after antigen-specific stimulation in comparison with stimulation without antigen. The analysis was made with whole peripheral blood.