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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
letter
. 2003 Jan;62(1):82–83. doi: 10.1136/ard.62.1.82

Adrenomedullin in synovial fluids from patients with rheumatoid arthritis inhibits interleukin 6 production from synoviocytes

Y Nanke 1, S Kotake 1, K Yonemoto 1, S Saito 1, T Tomatsu 1, N Kamatani 1
PMCID: PMC1754275  PMID: 12480679

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Figure 1 .

Figure 1

The concentration of mature AM was higher in patients with RA than in those with OA (p=0.01). Synovial fluids were obtained from nine patients with RA and six patients with OA.

Figure 2 .

Figure 2

Immunohistochemical staining using anti-AM antibody. AM was positive in endothelial cells in the RA synovium. Original magnification x200.

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